Patents by Inventor Georg Rainer

Georg Rainer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6124313
    Abstract: Imidazopyridine-azolidinones are useful for treating or preventing amenable gastro-intestinal ailments.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: September 26, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Gerhard Grundler, Jorg Senn-Bilfinger, Ulrich Thibaut, Georg Rainer
  • Patent number: 5719161
    Abstract: This invention relates to novel compounds of formula (I) and their therapeutic use in the treatment of gastrointestinal diseases.
    Type: Grant
    Filed: June 24, 1996
    Date of Patent: February 17, 1998
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 5665730
    Abstract: The invention relates to novel compounds of the formula I ##STR1## and the therapeutic use thereof.
    Type: Grant
    Filed: August 15, 1995
    Date of Patent: September 9, 1997
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Jorg Senn-Bilfinger, Gerhard Grundler, Georg Rainer
  • Patent number: 4758579
    Abstract: Dialkoxypyridines of formula I ##STR1## wherein R1 is 1-3C-alkyl which is completely or predominantly substituted by fluorine, or a chlorodifluoromethyl radical andR1' is hydrogen, halo, trifluoromethyl, 1-3C-alkyl, or 1-3C-alkoxy which is optionally completely or predominantly substituted by fluorine, orR1 and R1', together with the oxygen atom to which R1 is bonded, are 1-2C-alkylenedioxy, which is optionally completely or partly substituted by fluorine, or chlorotrifluoroethylenedioxy,R3 is 1-3C-alkoxy,one of R2 and R4 is 1-3C-alkoxy and the other is a hydrogen atom or 1-3C-alkyl andn is 0 or 1,and salts thereof are new compounds with a pronounced protective action on the stomach. Processes for preparing these compounds, medicaments containing them and their use, as well as intermediate compounds and their use for preparing the subject dialkoxypyridines, are disclosed.
    Type: Grant
    Filed: April 28, 1987
    Date of Patent: July 19, 1988
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Bernhard Kohl, Ernst Sturm, Georg Rainer
  • Patent number: 4686230
    Abstract: Picoline derivatives of the formula I ##STR1## wherein the substituents have the meanings given in the description, and their salts are new compounds having a pronounced protective action on the stomach.
    Type: Grant
    Filed: October 29, 1985
    Date of Patent: August 11, 1987
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Georg Rainer, Volker Figala, Bernhard Kohl
  • Patent number: 4560693
    Abstract: Tricyclic ethers of the general formula I ##STR1## wherein R represents a bond and R1 represents a 1-2C-alkylene radical which is completely or partly substituted by fluorine, or a chlorotrifluoroethylene radical, or R and R1 each represent a difluoromethylene radical, R2 represents hydrogen or a 1-3C-alkyl radical, R3 represents hydrogen or a 1-3C-alkyl or 1-3C-alkoxy radical, R4 represents hydrogen or a 1-3C-alkyl radical and n represents the number 0 or 1, and their salts are new compounds with a marked protective effect on the stomach.
    Type: Grant
    Filed: May 1, 1984
    Date of Patent: December 24, 1985
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4555518
    Abstract: Fluoroalkoxy compounds of the general formula I ##STR1## wherein R1 represents a 1-3C-alkyl radical which is completely or predominantly substituted by fluorine, or a chlorodifluoromethyl radical, R1' represents hydrogen, halogen, trifluoromethyl, a 1-3C-alkyl radical, or a 1-3C-alkoxy radical which is optionally completely or predominantly substituted by fluorine, R2 represents hydrogen or a 1-3C-alkyl radical, R3 represents hydrogen or a 1-3C-alkyl or 1-3C-alkoxy radical, R4 represents hydrogen or a 1-3C-alkyl radical and n represents the number 0 or 1, and their salts are new compounds with a marked protective effect on the stomach.
    Type: Grant
    Filed: May 1, 1984
    Date of Patent: November 26, 1985
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4381301
    Abstract: Substituted thienobenzodiazepinones of the general formula I ##STR1## [wherein R.sup.1 denotes a hydrogen atom (--H) or an alkyl radical with 1 to 4 carbon atoms; R.sup.2 represents a halogen atom (halo) or has one of the meanings of R.sup.1 ; R.sup.3 denotes a halogen atom (halo) or the group --N(R.sup.4)R.sup.5 ; R.sup.4 denotes an alkyl radical with 1 to 4 carbon atoms or an alkenyl radical with 3 to 5 carbon atoms; R.sup.5 has one of the meanings of R.sup.4 or represents the group --(CH.sub.2).sub.m --N(R.sup.6)R.sup.7 ; or R.sup.4 and R.sup.5, together with the nitrogen atom to which both are bonded, denote a morpholino group, a pyrrolidino group, a piperidino group, a hexahydroazepin-1-yl group, a piperazin-1-yl group (which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group), a 2,4-dimethylpiperazin-1-yl group, or a hexahydro-1H-1,4-diazepin-1-yl group (which is substituted in the 4-position by a methyl or ethyl group); R.sup.
    Type: Grant
    Filed: August 4, 1980
    Date of Patent: April 26, 1983
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4325962
    Abstract: Pyrazol-4-acetic acid compounds, such as substituted pyrazol-4-acetic acid, its esters, amides, nitriles and their pharmaceutically acceptable salts and method for the preparation of these compounds are disclosed. The novel compounds are useful analgesics, anti-inflammatory, and antipyretics.
    Type: Grant
    Filed: December 15, 1978
    Date of Patent: April 20, 1982
    Assignee: Byk-Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4317823
    Abstract: 1-(Lower)alkyl-4-(substituted)aminoalkylcarbonyl-1,4,9,10-tetrahydropyrazol o[4,3-b][1,5]benzodiazepin-10-ones are useful, e.g., to protect warm blooded animals against the formation of gastric ulcers. They are active ingredients in otherwise conventional medicament compositions administered enterally or parenterally in standard dosage forms. Their synthesis, their novel intermediates and their acid-addition salts are described.
    Type: Grant
    Filed: August 4, 1980
    Date of Patent: March 2, 1982
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4239901
    Abstract: Pyrazol-1-ylphenylacetic acids of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are the same or different and denote a hydrogen atom or a halogen atom,R.sup.4 denotes a hydrogen atom or an alkyl group,A B denotes a carbon-carbon single or double bond, and their salts are pharmacologically active and are useful as medicaments. Medicament compositions are produced therefrom. Their functional carboxylic acid derivatives and other new intermediates are used in their preparation.
    Type: Grant
    Filed: October 12, 1977
    Date of Patent: December 16, 1980
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4146721
    Abstract: Pyrazol-4-acetic acid compounds, such as substituted pyrazol-4-acetic acid, its esters, amides, nitriles and their pharamaceutically acceptable salts and method for the preparation of these compounds are disclosed. The novel compounds are useful analgesics, anti-inflammatory, and antipyretics.
    Type: Grant
    Filed: September 14, 1970
    Date of Patent: March 27, 1979
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4093812
    Abstract: 3-(5-Nitro-2-furyl)pyrazoles unsubstituted in the 5-position and 5-(5-nitro-2-furyl)pyrazoles unsubstituted in the 3-position are antimicrobials and disinfectants. The compounds are structurally represented by one of the formulae: ##STR1## wherein A is --CHO, --CN, --COOH, a protected or derived aldehyde group or a protected or derived carboxylic acid group;B is 5-nitro-2-furyl;R.sup.1 is --H, substituted or unsubstituted hydrocarbyl (saturated or unsaturated; acyclic, alicyclic or aromatic; or araliphatic); substituted or unsubstituted (cycloaliphatic or aromatic) heterocyclic or acyl (carboxylic or carbonic acid);R.sup.2 is --H; andn is a positive whole number of at most 2.
    Type: Grant
    Filed: March 23, 1976
    Date of Patent: June 6, 1978
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 4042702
    Abstract: 1,3-Diaryl-5-halogen-pyrazole-4-acetic acids and their derivatives with analgetic, antipyretic and antiphlogistic action are described.
    Type: Grant
    Filed: October 31, 1975
    Date of Patent: August 16, 1977
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 3974176
    Abstract: 1,3-Diaryl-5-halogen-pyrazole-4-acetic acids and their derivatives with analgetic, antipyretic and antiphlogistic action are described.
    Type: Grant
    Filed: August 5, 1975
    Date of Patent: August 10, 1976
    Assignee: Byk-Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Georg Rainer
  • Patent number: 3971770
    Abstract: Disazo dyestuffs free of sulfonic acid groups of the formula ##SPC1##Are disclosed in which R.sub.1 is phenyl, alkyl phenyl or C.sub.1 -C.sub.4 -alkyl; R.sub.2 is chlorine, bromine, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy; R.sub.3 and R.sub.4 which can be either identical or different, are hydrogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy; R.sub.5, R.sub.6 and R.sub.7, which can be either identical or different, are hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, halogen, carboxylic amide, carboxyl, or carboxylic ester; Y is hydroxyl or NR.sub.8 R.sub.9 ; R.sub.8 and R.sub.9 can be identical or different and are C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl or nitrile, or benzyl; and n is 0, 1 or 2. The dyestuffs are used in dyeing N-containing fiber materials.
    Type: Grant
    Filed: December 5, 1973
    Date of Patent: July 27, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Richard Sommer, Georg Rainer, Gerhard Wolfrum