Patents by Inventor Georg Seelig

Georg Seelig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240110227
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: December 12, 2023
    Publication date: April 4, 2024
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20240110226
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: December 12, 2023
    Publication date: April 4, 2024
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20240102080
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: December 12, 2023
    Publication date: March 28, 2024
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20240044908
    Abstract: Methods and kits for assessing and partially or uniquely identifying proteins, such as in complex mixtures of proteins and other molecules/structures, are described. In an embodiment, the methods include combinatorially barcoding target amino acid residues on the protein and, in certain embodiments, enzymatically cleaving the protein, such as before and after rounds of combinatorial barcoding. In an embodiment, the methods include (a) attaching a first nucleic acid molecule to target amino acid residues in the plurality of proteins in the sample to provide nascent nucleic acid tags at the target amino acid residues; (b) performing one or more rounds of split-pool barcoding to provide mature nucleic acid tags at the target amino acid residues (c) sequencing the mature nucleic acid tags; and (d) determining a frequency of the target amino acid residues in one or more protein of the plurality of proteins.
    Type: Application
    Filed: February 7, 2022
    Publication date: February 8, 2024
    Applicant: University of Washington
    Inventors: Georg SEELIG, Sergeii POCHEKAILOV, Peter J. MATULICH
  • Publication number: 20240002907
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: August 24, 2023
    Publication date: January 4, 2024
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230399680
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: August 24, 2023
    Publication date: December 14, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230392192
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: August 24, 2023
    Publication date: December 7, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230392193
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: August 24, 2023
    Publication date: December 7, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230340567
    Abstract: Methods of uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs and/or cDNAs.
    Type: Application
    Filed: April 21, 2023
    Publication date: October 26, 2023
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Georg SEELIG, Alexander B. ROSENBERG, Charles ROCO
  • Publication number: 20230304073
    Abstract: Methods of uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs and/or cDNAs.
    Type: Application
    Filed: April 21, 2023
    Publication date: September 28, 2023
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Georg SEELIG, Alexander B. ROSENBERG, Charles ROCO
  • Publication number: 20230295688
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: January 17, 2023
    Publication date: September 21, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230265487
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: March 23, 2023
    Publication date: August 24, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230227891
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: January 24, 2023
    Publication date: July 20, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230193351
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: July 25, 2022
    Publication date: June 22, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Patent number: 11680283
    Abstract: Methods of uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs and/or cDNAs.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: June 20, 2023
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Georg Seelig, Alexander B. Rosenberg, Charles Roco
  • Publication number: 20230139101
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: July 25, 2022
    Publication date: May 4, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Patent number: 11639519
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: May 2, 2023
    Assignee: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Patent number: 11634751
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: April 25, 2023
    Assignee: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20230014658
    Abstract: Methods of labeling or barcoding molecules within one or more portions of a plurality of cells are provided. Kits and systems for labeling or barcoding molecules within one or more portions of a plurality of cells are also provided. The methods, kits, and systems may utilize photo-controlled adapter sequences, nucleic acids tags, and/or linkers.
    Type: Application
    Filed: July 14, 2022
    Publication date: January 19, 2023
    Applicant: University of Washington
    Inventors: Georg Seelig, Anna Kuchina, Alexander B. Rosenberg
  • Patent number: 11555216
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Grant
    Filed: March 15, 2022
    Date of Patent: January 17, 2023
    Assignee: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg