Patents by Inventor George A. Ellestad

George A. Ellestad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazine containing anionic compounds useful as antiviral agents
    Patent number: 5852015
    Abstract: This invention provides triazine ring containing anionic compounds, pharmaceutical compositions containing these compounds and methods utilizing these compounds for treating viral infections, particularly infections by respiratory syncitial virus, the compounds having the general structure: ##STR1## and the pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 27, 1997
    Date of Patent: December 22, 1998
    Assignee: American Cyanamid Company
    Inventors: Yakov Gluzman, deceased, James P. LaRocque, Bryan M. O'Hara, John E. Morin, George A. Ellestad, Boris Mitsner, Wei-Dong Ding, Yuri E. Raifeld, Antonina A. Nikitenko
  • Process for preparing targeted forms of methyltrithio antitumor agents
    Patent number: 5770701
    Abstract: This disclosure describes a method for constructing targeting agent drug conjugates from the family of methyltrithio antibacterial and antitumor agents.
    Type: Grant
    Filed: October 26, 1994
    Date of Patent: June 23, 1998
    Assignee: American Cyanamid Company
    Inventors: William James McGahren, Martin Leon Sassiver, George A. Ellestad, Philip R. Hamann, Lois M. Hinman, Janis Upeslacis
  • Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methlytrithio group
    Patent number: 5770710
    Abstract: A process is described for producing substituted disulfide analogs of the family of antibacterial and antitumor agents known collectively as the LL-E33288 complex.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 23, 1998
    Assignee: American Cyanamid Company
    Inventors: William James McGahren, Martin Leon Sassiver, George A. Ellestad
  • Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
    Patent number: 5606040
    Abstract: This disclosure describes disulfide analogs of the family of antibacterial and antitumor agents known collectively as the LL-E33288 complex.
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: February 25, 1997
    Assignee: American Cyanamid Company
    Inventors: William J. McGahren, Martin L. Sassiver, George A. Ellestad
  • Antibiotic 42D005 .alpha. and .beta.
    Patent number: 5338729
    Abstract: This invention relates to antibiotic 42D005.alpha. and 42D005.beta. derived from the microorganism Kitasatosporia, which is useful as an antibacterial agent.
    Type: Grant
    Filed: April 26, 1993
    Date of Patent: August 16, 1994
    Assignee: American Cyanamid Company
    Inventors: Weidong Ding, George A. Ellestad, Darren Abbanat, Valerie Bernan
  • Targeted forms of methyltrithio antitumor agents
    Patent number: 5053394
    Abstract: This disclosure describes a method for constructing carrier-drug conjugates from the family of methyltrithio antibacterial and antitumor agents.
    Type: Grant
    Filed: April 14, 1989
    Date of Patent: October 1, 1991
    Assignee: American Cyanamid Company
    Inventors: George A. Ellestad, William J. McGahren, Martin L. Sassiver, Philip R. Hamann, Lois M. Hinman, Janis Upeslacis
  • Process for producing the antibiotic and antitumor agents LL-E33288.epsilon . .epsilon.-Br
    Patent number: 4996305
    Abstract: Processes for producing antibacterial and antitumor agents designated LL-E33288.epsilon.I and LL-E33288.epsilon.-Br using triphenylphosphine or a sulfhydryl-containing reagent are disclosed. Processes for producing reductively aromatized derivatives of other antibiotics are also disclosed.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: February 26, 1991
    Assignee: American Cyanamid Company
    Inventors: William J. McGahren, George A. Ellestad
  • Intermediate and process for producing the antibacterial and antitumor agents LL-E33288.epsilon.-I and LL-E33288Epsilon-Br
    Patent number: 4978748
    Abstract: Processes for producing antibacterial and antitumor agents designated LL-E33288.epsilon.-I and LL-E33288.epsilon.-Br using triphenylphosphine at ice bath temperature are disclosed. Novel intermediates prepared in the processes are also disclosed.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: December 18, 1990
    Assignee: American Cyanamid Company
    Inventors: George A. Ellestad, William J. McGahren
  • Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR
    Patent number: 4977143
    Abstract: Antibacterial and antitumor agents designated LL-E333288.epsilon.-I and LL-E33288.epsilon.-Br and their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and NRRL-18149, are disclosed.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: December 11, 1990
    Assignee: American Cyanamid Company
    Inventors: William J. McGahren, George A. Ellestad