Patents by Inventor George A. Fry
George A. Fry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20190338351Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: ApplicationFiled: July 15, 2019Publication date: November 7, 2019Inventors: George A. FRY, Christina E. INMAN, John BRIDGHAM, Timothy HUNKAPILLER, Charles S. VANN
-
Patent number: 10351907Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: GrantFiled: October 16, 2014Date of Patent: July 16, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: George A. Fry, Christina E. Inman, John Bridgham, Timothy Hunkapiller, Charles S. Vann
-
Publication number: 20150065356Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: ApplicationFiled: October 16, 2014Publication date: March 5, 2015Inventors: George A. FRY, Christina E. INMAN, John BRIDGHAM, Timothy HUNKAPILLER, Charles S. VANN
-
Patent number: 8889596Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: GrantFiled: August 16, 2013Date of Patent: November 18, 2014Assignee: Life Technologies CorporationInventors: George A. Fry, Christina E. Inman, John Bridgham, Timothy Hunkapiller, Charles S. Vann
-
Publication number: 20130331276Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: ApplicationFiled: August 16, 2013Publication date: December 12, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Mark F. OLDHAM, George A. FRY, Christina E. INMAN, John BRIDGHAM, Timothy HUNKAPILLER, Charles S. VANN
-
Patent number: 8536099Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: GrantFiled: August 31, 2010Date of Patent: September 17, 2013Assignee: Life Technologies CorporationInventors: Mark Oldham, George Fry, Christina Inman, John Bridgham, Timothy Hunkapillar, Charles Vann
-
Patent number: 8173198Abstract: Intermediates and methods for forming activated metal complexes bound to surfaces on oxide layers, immobilizing beads to the modified surface and articles produced thereby are described. Hydroxyl groups on the oxide surfaces are reacted with a metal reagent complex of the formula Y(L-Pol)m, where Y is a transition metal, magnesium or aluminum, L is oxygen, sulfur, selenium or an amine, and “Pol” represents a passivating agent such as a methoxyethanol, a polyethylene glycol, a hydrocarbon, or a fluorocarbon. The resulting modified surface can be further reacted with a passivating agent having a phosphate functional group or a plurality of functional groups that are reactive with or that form complexes with Y.Type: GrantFiled: July 23, 2009Date of Patent: May 8, 2012Assignee: Life Technologies CorporationInventors: Steven M. Menchen, Christina E. Inman, Meng Taing, George A. Fry
-
Publication number: 20110136677Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.Type: ApplicationFiled: August 31, 2010Publication date: June 9, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Mark OLDHAM, George Fry, Christina Inman, John Bridgham, Timothy Hunkapillar, Charles Vann
-
Patent number: 7797762Abstract: A cuff clip secures a loose trouser leg to a shoe, and support the lower edge of such trouser leg above the ground. A fastener is embedded within a lower portion of the shoe, leaving a coupling head exposed outside the shoe. The cuff clip engages the bottom edge of the trouser leg. The cuff clip includes a snap coupler that mates with the coupling head of the fastener embedded within the shoe. An outwardly-directed exterior wall of the cuff clip includes a bottom lip and opposing side lips to releasably receive a rectangular logo.Type: GrantFiled: June 5, 2006Date of Patent: September 21, 2010Inventors: Howard Shapiro, Ralph Farias, George Fry
-
Patent number: 7747253Abstract: Apparatus, and an associated method, for facilitating routing of a data service call background and foreground service delivery modes are defined. A delivery mode type determiner determines the service delivery mode associated with the data service. If the service delivery mode is a background delivery mode, the data service is effectuated with the intended receiving station instead of being redirected pursuant to a call forwarding, or other service interaction indicia, feature.Type: GrantFiled: January 29, 2004Date of Patent: June 29, 2010Assignee: Nokia CorporationInventor: George Fry
-
Publication number: 20100086927Abstract: Intermediates and methods for forming activated metal complexes bound to surfaces on oxide layers, immobilizing beads to the modified surface and articles produced thereby are described. Hydroxyl groups on the oxide surfaces are reacted with a metal reagent complex of the formula Y(L-Pol)m, where Y is a transition metal, magnesium or aluminum, L is oxygen, sulfur, selenium or an amine, and “Pol” represents a passivating agent such as a methoxyethanol, a polyethylene glycol, a hydrocarbon, or a fluorocarbon. The resulting modified surface can be further reacted with a passivating agent having a phosphate functional group or a plurality of functional groups that are reactive with or that form complexes with Y.Type: ApplicationFiled: July 23, 2009Publication date: April 8, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Steven M. Menchen, Christina E. Inman, Meng Taing, George A. Fry
-
Publication number: 20070277290Abstract: A cuff clip secures a loose trouser leg to a shoe, and supports the lower edge of such trouser leg above the ground. A fastener is secured to a lower portion of the shoe, leaving a coupling head or stud exposed outside the shoe. The cuff clip includes a channel to engage the bottom edge of the trouser leg. The cuff clip includes a snap coupler that mates with the coupling head or stud of the fastener embedded within the shoe. An exterior wall of the cuff clip is used to display a logo or other indicia. Such exterior wall has retaining lips to releasably receive indicia to be displayed thereon.Type: ApplicationFiled: June 5, 2006Publication date: December 6, 2007Inventors: Howard Shapiro, Ralph Farias, George Fry
-
Publication number: 20060087113Abstract: Pre-converted roll stock has a continuous web with printable surfaces that include a plurality of spaced registration marks for reference in positioning converting operations and image printing. The web has been pre-converted by application of remoistenable and pressure sensitive co-adhesive compositions, scratch off coatings, perforations, scores, notches, embossing and die cuts in preselected locations to form templates on the continuous web roll for a variety of printing and packaging applications, including printed pieces with self-mailers, return envelopes, reply cards, presentation folders, boxes and CD jackets. Selected registration marks are used to align an imaging device such as a digital press for printing the pre-converted stock with personalized variable data in the form of text and images.Type: ApplicationFiled: October 26, 2005Publication date: April 27, 2006Inventors: Aric Snyder, George Fry
-
Patent number: 6956839Abstract: Apparatus, and an associated method, for a radio, such as cellular, communication system to facilitate communications between a mobile station and the network infrastructure. When the mobile station registers in the communication system, a dedicated reverse-link channel is allocated to facilitate communications of packet data between the mobile station and the network infrastructure. By providing dedicated channels, the mobile station becomes functionally connected to the network infrastructure and are analogous to a hard wired connection of a computer in a local area network.Type: GrantFiled: April 26, 2002Date of Patent: October 18, 2005Assignee: Nokia CorporationInventors: Thomas A. Sexton, George Fry
-
Publication number: 20050130648Abstract: Apparatus, and an associated method, for facilitating routing of a data service call background and foreground service delivery modes are defined. A delivery mode type determiner determines the service delivery mode associated with the data service. If the service delivery mode is a background delivery mode, the data service is effectuated with the intended receiving station instead of being redirected pursuant to a call forwarding, or other service interaction indicia, feature.Type: ApplicationFiled: January 29, 2004Publication date: June 16, 2005Inventor: George Fry
-
Publication number: 20040117459Abstract: The invention provides a method and system for a network having multimedia messaging service (MMS) capability allowing downloading of one or more multimedia messages (MMs) from a server to a client. The client and/or the server is capable of generating commands for suspending and resuming downloading of the multimedia message. When the client or server generates a command for suspending a current downloading of a multimedia message, the server suspends the downloading of the multimedia message, and a marker is generated for marking the position of suspending the multimedia message. When the client or server generates a command for resuming the suspended downloading of the multimedia message, the server resumes the downloading from the position of suspending marked by the marker.Type: ApplicationFiled: December 12, 2002Publication date: June 17, 2004Inventor: George Fry
-
Patent number: 6697624Abstract: Apparatus, and an associated method, for facilitating routing of a data service call background and foreground service delivery modes are defined. A delivery mode type determiner determines the service delivery mode associated with the data service. If the service delivery mode is a background delivery mode, the data service is effectuated with the intended receiving station instead of being redirected pursuant to a call forwarding, or other service interaction indicia, feature.Type: GrantFiled: June 11, 2001Date of Patent: February 24, 2004Assignee: Nokia Mobile Phones Ltd.Inventor: George Fry
-
Patent number: 6638760Abstract: The present invention provides substrates and apparatuses for efficient, rapid and specific capture, and optimal recovery, of nucleic acids, as well as methods of their use. The substrate is porous in nature and has a capture polynucleotide capable of hybridizing to a target nucleic acid immobilized thereon. Upon flowing a sample containing or suspected of containing the target nucleic acid through the porous substrate, the target nucleic acid is rapidly captured. Following capture, the target nucleic acid can be efficiently recovered for subsequent use.Type: GrantFiled: December 3, 1998Date of Patent: October 28, 2003Assignee: PE Corporation (NY)Inventors: Jer-Kang Chen, Claudia Chiesa, George A. Fry, Vergine C. Furniss, Stephen M. Lambert, Roger O'Neill, Majid Mehrpouyan
-
Patent number: 6614772Abstract: Apparatus, and an associated method, for a radio, such as cellular, communication system to facilitate communications between a mobile station and the network infrastructure. When the mobile station registers in the communication system, a dedicated reverse-link channel is allocated to facilitate communications of packet data between the mobile station and the network infrastructure. By providing dedicated channels, the mobile station becomes functionally connected to the network infrastructure and are analogous to a hard wired connection of a computer in a local area network.Type: GrantFiled: March 1, 1999Date of Patent: September 2, 2003Assignee: Nokia CorporationInventors: Thomas A. Sexton, George Fry
-
Patent number: 6514699Abstract: The invention relates to methods and compositions for simultaneously generating a plurality of polynucleotide sequencing ladders or PCR amplification products. Each sequencing ladder is generated from a recoverable primer, i.e., an oligonucleotide primer comprising a recovery tag. The recovery tag may be an oligonucleotide. Each sequencing ladder has a unique recovery tag. After the generation of the multiple sequencing ladders, the different sequencing ladders are separated from one another, i.e., purified, by binding to recovery tag binding compounds that have been immobilized on one or more solid supports. The recovery tag binding compounds are immobilized on the solid support in an addressable manner, i.e., the recovery tag binding compounds have distinct locations on the solid support. The binding of the sequencing ladders to the recovery tag binding compounds serves to separate the different polynucleotide sequencing ladders present in a given solution.Type: GrantFiled: June 13, 2000Date of Patent: February 4, 2003Assignee: PE Corporation (NY)Inventors: Roger A. O'Neill, Jer-Kang Chen, Claudia Chiesa, George Fry