Patents by Inventor George A. Komatsoulis

George A. Komatsoulis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 49 human secreted proteins
    Patent number: 6566325
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: May 20, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
  • 49 human secreted proteins
    Publication number: 20030087341
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 25, 2002
    Publication date: May 8, 2003
    Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
  • 70 human secreted proteins
    Publication number: 20030069405
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: May 15, 2002
    Publication date: April 10, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Paul E. Young, Laurie A. Brewer, Reinhard Ebner, Henrik S. Olsen, Kimberly A. Florence, Craig A. Rosen, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Charles Florence, Daniel R. Soppet, Gregory A. Endress, Ping Feng, George A. Komatsoulis
  • Secreted protein HCEJQ69
    Publication number: 20030065151
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: April 4, 2002
    Publication date: April 3, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • Secreted protein HT5GJ57
    Patent number: 6534631
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: January 13, 2000
    Date of Patent: March 18, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
  • 62 human secreted proteins
    Publication number: 20030050442
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 18, 2002
    Publication date: March 13, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, George Komatsoulis, Craig A. Rosen, Daniel R. Soppet, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Reinhard Ebner, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Paul Young
  • TM4SF polynucleotides, polypeptides, and antibodies
    Publication number: 20030050466
    Abstract: The present invention relates to novel human TM4SF polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human TM4SF polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human TM4SF polypeptides.
    Type: Application
    Filed: March 22, 2002
    Publication date: March 13, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven M. Ruben, Ping Fan, Viktor Roschke, Yanggu Shi, George A. Komatsoulis, Craig A. Rosen
  • 31 human secreted proteins
    Publication number: 20030050460
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: September 10, 2001
    Publication date: March 13, 2003
    Inventors: Jian Ni, Steven M. Ruben, Craig A. Rosen, Reinhard Ebner, Kimberly A. Florence, Paul E. Young, Charles E. Birse, Kenneth C. Carter, George Komatsoulis
  • Secreted protein HCEJQ69
    Publication number: 20030044851
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 12, 2001
    Publication date: March 6, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul E. Young, Kimberly A. Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik S. Olsen, Yanggu Shi, Paul A. Moore, George A. Komatsoulis
  • Secreted protein HT5GJ57
    Publication number: 20030040088
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 29, 2001
    Publication date: February 27, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik S. Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul E. Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
  • Uncoupling protein polynucleotides, polypeptides, and antibodies
    Publication number: 20030036646
    Abstract: The present invention relates to novel human uncoupling polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human uncoupling polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human uncoupling polypeptides.
    Type: Application
    Filed: April 5, 2002
    Publication date: February 20, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven M. Ruben, George A. Komatsoulis, Craig A. Rosen, Daniel R. Soppet
  • 19 human secreted proteins
    Publication number: 20030027297
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: April 11, 2001
    Publication date: February 6, 2003
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • 143 human secreted proteins
    Publication number: 20030027999
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: November 8, 2001
    Publication date: February 6, 2003
    Inventors: Craig A. Rosen, Steven M. Ruben, Paul A. Moore, Paul E. Young, George A. Komatsoulis, Charles E. Birse, Roxanne D. Duan, Kimberly A. Florence, Daniel R. Soppet
  • Secreted protein HT5GJ57
    Publication number: 20030017500
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 29, 2001
    Publication date: January 23, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
  • 94 Human Secreted Proteins
    Patent number: 6475753
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: November 5, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. Lafleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • Secreted protein HNFGF20
    Patent number: 6476195
    Abstract: The present invention relates to novel human secreted protein (HNFGF20). Polypeptides of the invention are duseful in dianosis and treatment of disorders affecting the immune system.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: November 5, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Ying-Fei Wei, Jian Ni, Kimberly A. Florence, Paul Young, Laurie A. Brewer, Daniel R. Soppet, Gregory A. Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • 17 human secreted proteins
    Publication number: 20020120103
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 27, 2001
    Publication date: August 29, 2002
    Inventors: Craig A. Rosen, George A. Komatsoulis, Kevin P. Baker, Charles E. Birse, Daniel R. Soppet, Henrik S. Olsen, Paul A. Moore, Ping Wei, Reinhard Ebner, D. Roxanne Duan, Yanggu Shi, Gil H. Choi, Michele Fiscella, Jian Ni, Steven M. Ruben, Steven C. Barash
  • 31 human secreted proteins
    Publication number: 20020076705
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 30, 2001
    Publication date: June 20, 2002
    Inventors: Steven M. Ruben, Craig A. Rosen, Roxanne D. Duan, Yanggu Shi, David W. LaFleur, Paul E. Young, Jian Ni, George Komatsoulis, Gregory A. Endress, Daniel R. Soppet
  • 32 human secreted proteins
    Publication number: 20020068319
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 8, 2001
    Publication date: June 6, 2002
    Inventors: Jian Ni, Kevin P. Baker, Charles E. Birse, Reinhard Ebner, Michele Fiscella, George A. Komatsoulis, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Ping Wei, Kimberly A. Florence
  • 52 human secreted proteins
    Publication number: 20020064818
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: February 22, 2001
    Publication date: May 30, 2002
    Inventors: Jian Ni, Kevin P. Baker, Charles E. Birse, Michele Fiscella, George A. Komatsoulis, Craig A. Rosen, Daniel R. Soppet, Paul E. Young, Reinhard Ebner, D. Roxanne Duan, Henrik S. Olsen, David W. LaFleur, Paul A. Moore, Yanggu Shi, Ping Wei, Kimberly A. Florence