Patents by Inventor George A. Williams

George A. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11231478
    Abstract: Techniques are disclosed for acquiring MR signals of an object under examination in an MR system using a multi echo imaging sequence. The method comprises the steps of applying an RF excitation pulse to the object to generate a transverse magnetization, applying at least two RF refocusing pulses for refocusing the transverse magnetization to generate at least two MR spin echoes for the RF excitation pulse, applying a first magnetic field gradient in a read out direction between the RF excitation pulse and the first of the at least two RF refocusing pulses, applying a second magnetic field gradient in the read out direction after each of the at least two RF refocusing pulses such that the zeroth and first gradient moment is substantially zero for the second magnetic field gradient, and acquiring the at least two MR spin echoes during the at least two second magnetic field gradients.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: January 25, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Constantin von Deuster, George William Ferguson, Michael Koehler
  • Patent number: 11219821
    Abstract: Examples are disclosed that relate to computing device input systems. In one example, a computing device input system comprises an input configured to receive a connection to a control device connector comprising a plurality of conductors. The computing device input system further comprises circuitry configured to determine a presence, type, and state of a control device in communication with the control device connector based on analog voltages received from the control device connector.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: January 11, 2022
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: George William Bielitz, Ross Anthony Nelson, Sam Michael Sarmast
  • Patent number: 11219445
    Abstract: Methods of tissue repair. At least one example method includes: pulling a tissue in place over a bone location; abutting a distal end of a guide tool against the tissue at a first location, and driving a first bone anchor through a delivery tube of the guide tool, through the tissue, and into the bone at the first location, the first bone anchor coupled to a first suture line; abutting the distal end of the guide tool against the tissue at a second location displaced from the first location, and then driving a second bone anchor through the delivery tube, through the tissue, and into the bone at the second location, the second bone anchor associated with the first suture line; withdrawing the guide tool away from the tissue; and tightening the first suture line to create a first suture over the tissue.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: January 11, 2022
    Inventors: Donald A. Williams, George J. Sikora
  • Publication number: 20210395751
    Abstract: The present disclosure relates to compositions and methods for treating viral infections and in particular for treating hepatitis B and hepatitis D viral infections. A method of treating a hepatitis B virus infection in a subject the method comprising administering to the subject an inhibitor wherein the inhibitor inhibits or suppresses a regulator of liver lipid metabolism in the subject.
    Type: Application
    Filed: October 24, 2019
    Publication date: December 23, 2021
    Inventors: Mark William Douglas, Mohammed Eslam, George Jacob, Anis Khan
  • Patent number: 11203170
    Abstract: A method of manufacturing a 3-dimensional variable refractive-index optical-element with surface figure, the method comprising: depositing a plurality of nanocomposite-inks comprising an organic-matrix with a nanoparticle filler dispersed within, and at least partially curing a portion of the nanocomposite-ink to form a nanocomposite slab that is at least semi-solid; transferring the nanocomposite slab to a press, the press having a die mold with at least a first surface figure; and actuating the press to compress the nanocomposite slab and impart the die mold's first surface figure onto the nanocomposite slab to form a nanocomposite optical-element.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: December 21, 2021
    Inventor: George Williams
  • Publication number: 20210388228
    Abstract: A coating composition includes: (a) a phosphorus acid functional polyol polymer having an acid value within a range of greater than 7 mg KOH/g and 33 mg KOH/g or less, and a hydroxyl value within a range of from 60 to 200 mg KOH/g; (b) an aminoplast derived crosslinker reactive with the phosphorus acid functional polyol polymer; and (c) a non-aqueous liquid medium. Further, if an external catalyst is present, the coating composition comprises less than 0.25 weight % of the external catalyst based on the total weight of the coating composition. The coating composition cures at a temperature of 100° C. or less.
    Type: Application
    Filed: November 1, 2019
    Publication date: December 16, 2021
    Applicant: PPG Industries Ohio, Inc.
    Inventors: Christopher A. Verardi, Susan F. Donaldson, Paul H. Lamers, Karen Morrow, George William Maurer, III, Steven Victor Barancyk
  • Patent number: 11180668
    Abstract: An apparatus with integrated optical waveguides. The apparatus has: a plurality of layers, wherein a conductive pathway is patterned on a surface of at least one of the plurality of layers. The plurality of layers are laminated together. A plurality of nanocomposite-inks, each with a nanofiller dispersed in an organic matrix have optical dispersion different from the other plurality of nanocomposite-ink, form the optical waveguides. The optical waveguides are formed on the surface of, or within, at least one of the plurality of layers.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: November 23, 2021
    Inventor: George Williams
  • Patent number: 11179415
    Abstract: The use of chlorine dioxide (CLO2) to kill or disable pathogens such as viruses, particularly those of the Coronavirus family. A certain amount of CLO2 is used via different modalities, particularly through one's nose or mouth, as a therapeutic. CLO2 can treat, cure and/or prevent diseases, such as methicillin resistant Staphylococcus aureus (MRSA), fungal infections, the common cold, and more particularly a current disease in the year 2020, known as COVID-19. The invention will not only kill or disable SARS CoV-2, which causes COVID-19, but will also kill or disable the next Coronavirus, SARS CoV-3, once CoV-2 mutates and escapes any vaccine against it.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: November 23, 2021
    Inventor: George William Madray
  • Patent number: 11174400
    Abstract: A method of manufacturing a nanocomposite GRIN optical-element. The method comprises providing a volumetric gradient refractive profile and providing a plurality of nanocomposite-inks to form the GRIN optical-element. Each of the plurality of nanocomposite-inks have nanoparticles dispersed in an organic-matrix. The plurality of nanocomposite-inks comprising of a nanoparticle diffusion inhibiting nanocomposite-ink wherein nanoparticle diffusion is inhibited with respect to another of the plurality of nanocomposite-inks. The diffusion inhibiting nanocomposite-ink having a different dielectric property from at least one of the other plurality of nanocomposite-inks. The plurality of nanocomposite-inks also comprising a nanoparticle diffusion permitting nanocomposite-ink wherein nanoparticle diffusion is permitted with respect to at least another of the plurality of nanocomposite-inks.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: November 16, 2021
    Inventors: George Williams, John Paul Harmon, Charles G. Dupuy, Ngoc Thanh Nguyen
  • Publication number: 20210330810
    Abstract: The invention provides compositions containing cargo molecules attached to elements that improve the function of the cargo molecules in the body of a subject. The compositions are useful for therapeutic and diagnostic purposes. Furthermore, the invention outlines ways in which these compositions can be produced; the core molecule can be functionalized, via bioorthogonal click chemistry, in such a way as to impart modular characteristics. This functionalization simultaneously allows for loading of biologically relevant cargo and provides stabilization to the overall structure of the molecule.
    Type: Application
    Filed: April 27, 2021
    Publication date: October 28, 2021
    Inventors: James Luke Rushworth, George William Foot, Anna Perdrix Rosell, Zuzanna Aleksandra Brzosko
  • Publication number: 20210322609
    Abstract: A hydrogen peroxide sterilization device for sterilizing a medical device, the hydrogen peroxide sterilization device including a hermetic outer container, a hydrogen peroxide pouch, and a hydrogen peroxide solution in the solution chamber. The hermetic outer container includes a sterilization enclosure configured to receive the medical device. The hydrogen peroxide pouch includes a permeable membrane enclosing a solution chamber and is configured to be positioned in the sterilization enclosure of the outer container. The permeable membrane is configured to allow hydrogen peroxide vapor to diffuse from the solution chamber through the permeable membrane into the sterilization enclosure.
    Type: Application
    Filed: September 3, 2020
    Publication date: October 21, 2021
    Applicant: Honeywell Federal Manufacturing & Technologies, LLC
    Inventors: George William Bohnert, Darren Radke, Domenick Leto
  • Publication number: 20210289307
    Abstract: In various applications, the system provides a method for processing audio signals, including: receiving a request for audio content; receiving an identifier encoded in a personal audio device comprising a transducer for playing audio; retrieving at least one parameter associated with the identifier; and processing the audio content using at least the request, the identifier and the at least one parameter, wherein the processing is customized for the personal audio device based on the at least one parameter associated with the identifier.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 16, 2021
    Inventor: George William Daly
  • Publication number: 20210275549
    Abstract: Provided are novel formulations of 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate as described below and uses thereof.
    Type: Application
    Filed: November 16, 2020
    Publication date: September 9, 2021
    Applicant: Aeromics, Inc.
    Inventors: Marc F. PELLETIER, Paul Robert MCGUIRK, George William FARR
  • Patent number: 11095328
    Abstract: A wireless access point serves dynamic direction-of-arrival reception. An access point radio wirelessly receives a wireless signal that transports time-domain data. Access point circuitry determines uplink utilization for the access point radio. The circuitry transforms the time-domain data into frequency-domain data. The circuitry filters the frequency-domain data for one direction-of-arrival responsive to the uplink utilization. The circuitry synthesizes the time-domain data from the filtered frequency-domain data. The radio wirelessly receives another wireless signal that transports additional time-domain data. The circuitry determines a higher uplink utilization for the access point radio. The circuitry transforms the additional time-domain data into additional frequency-domain data. The circuitry filters the additional frequency-domain data for multiple directions-of-arrival responsive to the higher uplink utilization.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: August 17, 2021
    Assignee: Sprint Communications Company L.P.
    Inventors: Sanghoon Sung, Yu Wang, Udit A. Thakore, George William Harter, III
  • Patent number: 11084778
    Abstract: The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., diseases of water imbalance, for example edema (particularly edema of the brain and spinal cord, e.g., following trauma or ischemic stroke, as well as the edema associated with glioma, meningitis, acute mountain sickness, epileptic seizures, infections, metabolic disorders, hypoxia, water intoxication, hepatic failure, hepatic encephalopathy, diabetic ketoacidosis, abscess, eclampsia, Creutzfeldt-Jakob disease, and lupus cerebritis, as well as edema consequent to microgravity and/or radiation exposure, as well as edema consequent to invasive central nervous system procedures, e.g.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: August 10, 2021
    Assignee: AEROMICS, INC.
    Inventors: Marc F. Pelletier, George William Farr, Paul Robert McGuirk, Christopher H. Hall, Walter F. Boron
  • Patent number: 11071744
    Abstract: Provided are novel prodrug salts of selective aquaporin inhibitors, their use as pharmaceuticals, and pharmaceutical compositions comprising them, and novel processes for their synthesis and novel intermediates for use in their synthesis. Also provided is use of a compound for the prophylaxis, treatment, and control of aquaporin-mediated conditions. Aquaporin inhibitors, e.g., inhibitors of AQP4 and/or AQP2, may be of utility in the treatment or control of diseases of water imbalance, for example edema (particularly edema of the brain and spinal cord), hyponatremia, and excess fluid retention, as well as diseases such as epilepsy, retinal ischemia and other diseases of the eye, myocardial ischemia, myocardial ischemia/reperfusion injury, myocardial infarction, myocardial hypoxia, congestive heart failure, sepsis, and neuromyelitis optica, as well as migraines.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: July 27, 2021
    Assignee: AEROMICS, INC.
    Inventors: Marc F. Pelletier, Paul Robert McGuirk, George William Farr, Robert Zamboni, John Colucci, Helmi Zaghdane
  • Publication number: 20210214728
    Abstract: The invention provides compositions for delivery of cargo to cells. The invention also provides compositions that bind multiple agents simultaneously. The compositions are useful as therapeutics. Methods of using the compositions are also provided.
    Type: Application
    Filed: February 19, 2021
    Publication date: July 15, 2021
    Applicant: Sixfold Bioscience Ltd.
    Inventors: George William Foot, Anna Perdrix Rosell, Zuzanna Aleksandra Brzosko
  • Patent number: 11061087
    Abstract: A method includes determining a position of a local coil, a coil position, and a position of a body part of a patient, a body part position. Spacing between the coil position and the body part position is determined. An optimized MR sequence is determined. Based on the determined spacing between the coil position and the body part position, it is checked that in a subsequent MR examination of the patient, a predetermined loading threshold value (e.g., an SAR value) is not exceeded. The optimization of the MR sequence thus takes place under the boundary condition that the loading threshold value is not exceeded.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: July 13, 2021
    Assignee: Siemens Healthcare GmbH
    Inventors: George William Ferguson, Martin Harder, Daniel Rinck
  • Publication number: 20210212158
    Abstract: A real-time application-based cellular system with real-time GPS positioning to notify civilian drivers of the proximity of emergency services vehicles in sufficient time to allow appropriate response. Civilian users receive alerts and information on their personal computing devices, including, but not limited to, tablets and smart phones. No addition or special hardware is required. Only drivers in a moving vehicle with a certain proximity are directly and selectively notified. The system also is able to send other additional customized warning signals to citizens in threatening situations in a non-vehicular context.
    Type: Application
    Filed: January 8, 2021
    Publication date: July 8, 2021
  • Publication number: 20210191443
    Abstract: Techniques for providing electric power are disclosed. In one aspect, an adapter module is retrofit inline with an existing power source for moderating the supply of power via an outlet. In response to receiving a confirmation that a wireless payment has been tendered, the module automatedly activates a switch to provide power to an identified outlet for a predetermined time or until the user device is charged. In another aspect, an adapter module provides a power or data service responsive to information provided by a user via a mobile application. In either case using the retrofit adapter module, payments can be made available using existing infrastructures with only the need for the adapter module.
    Type: Application
    Filed: December 20, 2019
    Publication date: June 24, 2021
    Inventors: George William Melcer, Charles Karim Aweida