Abstract: A graphically based tool and method for generating programming for a fire monitoring system. The locations of existing devices, such as detectors, in a building being monitored, can be visually presented in the context of the building. New devices can be installed, or the location of existing devices changed since all devices report their locations in the building to the tool. Device location information can be combined with building information to create a multi-dimensional representation of parts of the building being monitored.

Abstract: An electrosurgical apparatus comprising an electrosurgical forceps instrument that combines la robust jaw opening mechanism with an a microwave energy delivery mechanism. The instrument includes a rigid bracket mounted at a distal end of a flexible shaft, wherein a pair of jaws are pivotably mounted on the rigid bracket. The instrument includes an energy delivery structure comprising a flexible dielectric substrate having a first electrode and an second electrode formed on one of the pair of jaws, wherein the first electrode and the second electrode are arranged to emit microwave energy. The electrosurgical apparatus may also comprise a handpiece that combines rotation control of an electrosurgical instrument with both power delivery and end effector actuation (e.g. jaw closure, blade retraction or the like).

Abstract: In an aspect, the present invention provides a high frequency switching power converter. The high frequency switching power converter may include a plurality of soft-switchable power cells flexibly connected to receive an input signal in series and provide an output. The high frequency switching power converter may further include a controller for configuring the flexible connection and for controlling the power cells to receive the input signal. In an embodiment, each of the plurality of power cells may be separately controllable by the controller. Further, a portion of the plurality of power cells may be arranged with parallel outputs. Additionally, at least one of the plurality of cells may include one or more switched capacitors. In another embodiment, the at least one of the plurality of cells may include at least one switched capacitor and a DC/DC regulating converter.

Abstract: Methods and systems for distinguishing an astrocytic human brain tumor from a non-astrocytic human brain tumor. In one embodiment, a method includes the steps of staining tumor tissue from a subject suspected of having a brain tumor with SR101 and visualizing the tissue stained with SR101 with a fluorescence imaging device to confirm an astrocytic or non-astrocytic tumor type. Advantageously, tumor tissue from a subject is stained ex vivo, and the staining and visualizing steps are performed intraoperatively so as to guide the surgeon and thereby minimize or eliminate the need for a subsequent surgery.

Abstract: The invention relates to new quinoxaline, quinoline and quinazolinone derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: A device and method for treating a hone includes a bone plate including first and second portions joined to one another via a connecting portion, a rigidity of the connecting portion being less than rigidities of each of the first and second portions in combination with a first sensor mounted on the first portion measuring strain on the first portion and a second sensor mounted on the second portion measuring strain on the second portion.

Abstract: The disclosure is directed to a feeding system. The feeding system includes a housing that substantially forms an exterior surface of the feeding system, inside the housing includes an arm configured to rotate clockwise and counterclockwise to a plurality of positions, wherein the arm is configured to support a can; a can opener at a first position of the plurality of positions; and an opening of the housing at a second position of the plurality of positions.

Abstract: The present invention provides methods for treating an allergy by administering one or more antibodies that bind specifically to the allergen. In certain embodiments, the antibodies useful for treating an allergen, bind specifically to the cat allergen, Fel d1. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to Fel d1. The antibodies of the invention are useful for binding to the Fel d1 allergen in vivo, thus preventing binding of the Fel d1 allergen to pre-formed IgE on the surface of mast cells or basophils. In doing so, the antibodies act to prevent the release of histamine and other inflammatory mediators from mast cells and/or basophils, thus ameliorating the untoward response to the cat allergen in sensitized individuals.

Abstract: The disclosed technology is generally directed to device certification in an IoT environment. For example, such technology is usable in managing relationships between IoT devices and an IoT Hub. In one example of the technology, an IoT Hub receives a registration request. Next, the IoT Hub sends a registration verification to the IoT device. Next, the IoT Hub receives a ping from the IoT device. Next, the IoT Hub sends a response to the ping to the IoT device. Next, the IoT Hub receives verification of a validation of a log file output by a device based on running a plurality of unit tests on a device with a software development kit. Next, the IoT Hub automatically sends code to the IoT device.

Abstract: An illustrative example method of controlling an elevator situated in a hoistway of a building includes detecting sway of the building, determining characteristics of the detected sway including a plurality of frequencies and associated periods of the sway, determining an expected sway of an elongated member of the elevator system based on the determined characteristics, and controlling at least one of position and movement of an elevator car in the hoistway based on the expected sway.

Abstract: Features for high intensity focused ultrasound (HIFU) are described. The application of HIFU for ablating tissue may be monitored in real time by imaging bubbles generated during HIFU. A single transducer array may be used by fast switching between imaging and HIFU. For imaging, the array or portions thereof may be used in receive only mode to locate bubbles generated by the HIFU. The application of HIFU, such as location and/or intensity, may be adjusted based on information from the imaging of the bubbles. Physicians and/or others may use these systems and methods to monitor HIFU procedures in real-time for optimal ablation of target tissue with minimal damage to healthy tissue.

Abstract: A fastener including a screw receiving element extending along a first axis and having a first end and a second end, the screw receiving element including a through hole extending through a thickness of the screw receiving element perpendicular to the first axis, the fastener further including a retention element arranged at the first end of the screw receiving element, wherein the retention element is plate-shaped and extends in a direction perpendicular to the first axis of the screw receiving element, and the retention element further includes a panel facing surface extending in a plane substantially perpendicular to the first axis of the screw receiving element, and side surfaces extending in planes substantially along the first axis of the screw receiving element.

Abstract: Disclosed herein are quantum dot devices with conductive liners, as well as related computing devices and methods. For example, in some embodiments, a quantum dot device may include a base, a first fin extending from the base, a second fin extending from the base, a conductive material between the first fin and the second fin, and a dielectric material between the conductive material and the first fin.

Abstract: One example is directed to a reader device having a first resonance circuit and being configured to interrogate one or more other remotely-located resonance circuits, each associated with a second resonance circuit which may be part of a passive sensor circuit. The first resonance circuit is operated to cause the inductively-coupled oscillating signal to be swept over a range of frequencies and therein cause a jump or sudden transition in a frequency of the oscillating signal while the first and second resonance circuits are in sufficient proximity for inductively-coupling via an oscillating signal via their respective resonance circuits. Sensing circuitry may be used to detect the jump or sudden transition in the frequency of the oscillating signal and, by way of or in response to an indication of timing and/or a set of inductively-related parameters, data is conveyed from the sensor to the reader device via the inductively-coupled oscillating signal.

Abstract: The invention relates to new quinoline, pyridopyrazine, naphthyridine and quinazolinone derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: The present disclosure provides methods and systems for performing a microwave digestion of a sample contained in a sample recipient. The method comprises acquiring images of at least one sample recipient inside a primary cavity of a microwave digestion system during microwave digestion of a sample inside the at least one sample recipient, and monitoring the microwave digestion using the images of the at least one sample recipient.

Abstract: The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

Abstract: A computer controlled robotic system that autonomously adjusts the location of a floating marine dock whenever water levels change in a body of water (e.g., a lake or reservoir) to maintain sufficient draft clearance for safe boat operation and ensure safe access to the dock. The system is comprised of an electric motor-driven tractor device attached to the shore-end of a walkway and a pair of electric-motor driven cable winch assemblies with a distributed control system to move the floating dock toward or away from the shore to maintain a relative desired water depth for safe boat operation and positioning in relation to the moving edge of the water shoreline.

Abstract: A beverage forming method and system arranged to allow a user to change one or more brew parameters used by a beverage machine control circuit to perform automatic control during a beverage dispensing operation. For example, a user can adjust a volume of a beverage to be dispensed while the beverage is being dispensed in the user's cup, and the control circuit will adjust automatic control of the dispensing process based on the adjusted volume from the user.

Abstract: A device for controlling a fluid flow in an array of fluid pathways on a microfluidic chip is provided. The device comprising: two or more resistors provided upstream of the chip wherein each upstream resistor is configured to provide a resistance at an upstream end of a fluid pathway; two or more resistors provided downstream of the chip wherein each downstream resistor is configured to provide a resistance at a downstream end of a fluid pathway, wherein the values of the resistances are selected in order to control a proportion of fluid that flows through each fluid pathway.