Patents by Inventor George B. Witman

George B. Witman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8309691
    Abstract: The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: November 13, 2012
    Assignees: University of Massachusetts, Yale University
    Inventors: George B. Witman, Gregory J. Pazour, Joel L. Rosenbaum, Douglas G. Cole
  • Publication number: 20120046448
    Abstract: The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods.
    Type: Application
    Filed: July 22, 2011
    Publication date: February 23, 2012
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: George B. Witman, Gregory J. Pazour, Joel L. Rosenbaum, Douglas G. Cole
  • Patent number: 7985583
    Abstract: The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety, of diagnostic, screening, and therapeutic methods.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: July 26, 2011
    Assignees: Univeristy of Massachusetts, Yale University
    Inventors: George B. Witman, Gregory J. Pazour, Joel L. Rosenbaum, Douglas G. Cole
  • Publication number: 20100267130
    Abstract: The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety, of diagnostic, screening, and therapeutic methods.
    Type: Application
    Filed: June 9, 2009
    Publication date: October 21, 2010
    Inventors: George B Witman, Gregory J. Pazour, Joel L. Rosenbaum, Douglas G. Cole
  • Patent number: 7690446
    Abstract: A roller cone drill bit is disclosed which includes a bit body adapted to be coupled to a drill string. A bearing journal depends from the bit body. A single roller cone is rotatably attached to the bearing journal. The roller cone has a plurality of inserts disposed at selected positions about the cone. The journal defines a rotation angle with respect to an axis of rotation of the bit such that the roller cone includes a wall contact zone and a bottom contact zone. At least one of the inserts disposed in the wall contact zone has an extension portion terminating in a substantially planar upper surface.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: April 6, 2010
    Assignee: Smith International, Inc.
    Inventors: George B. Witman, Peter Wilson, Scott D. McDonough, Michael A. Siracki
  • Patent number: 7665547
    Abstract: A rotary rock bit includes a lubricant reservoir with a pressure compensation assembly disposed therein. The pressure compensation assembly is adapted to permit selective adjustment of the relief pressure set by the assembly through the selective adjustment of one member in the assembly with respect to another member in the assembly.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: February 23, 2010
    Assignee: Smith International, Inc.
    Inventors: Zhou Yong, George B. Witman, IV, Carlos Torres
  • Patent number: 7553674
    Abstract: The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods.
    Type: Grant
    Filed: May 5, 2004
    Date of Patent: June 30, 2009
    Assignees: University of Massachusetts, Yale University
    Inventors: George B. Witman, Gregory J. Pazour, Joel L. Rosenbaum, Douglas G. Cole
  • Publication number: 20080121435
    Abstract: A roller cone drill bit is disclosed which includes a bit body adapted to be coupled to a drill string. A bearing journal depends from the bit body. A single roller cone is rotatably attached to the bearing journal. The roller cone has a plurality of inserts disposed at selected positions about the cone. The journal defines a rotation angle with respect to an axis of rotation of the bit such that the roller cone includes a wall contact zone and a bottom contact zone. At least one of the inserts disposed in the wall contact zone has an extension portion terminating in a substantially planar upper surface.
    Type: Application
    Filed: February 6, 2008
    Publication date: May 29, 2008
    Applicant: SMITH INTERNATIONAL, INC.
    Inventors: George B. Witman, Peter Wilson, Scott D. McDonough, Michael A. Siracki
  • Publication number: 20080105467
    Abstract: A rotary rock bit includes a lubricant reservoir with a pressure compensation assembly disposed therein. The pressure compensation assembly is adapted to permit selective adjustment of the relief pressure set by the assembly through the selective adjustment of one member in the assembly with respect to another member in the assembly.
    Type: Application
    Filed: November 17, 2006
    Publication date: May 8, 2008
    Inventors: Zhou Yong, George B. Witman, Carlos Torres
  • Patent number: 7100711
    Abstract: A roller cone drill bit is disclosed which includes a bit body adapted to be coupled to a drill string. A bearing journal depends from the bit body. A single roller cone is rotatably attached to the bearing journal. The roller cone has a plurality of inserts disposed at selected positions about the cone. The journal defines a rotation angle with respect to an axis of rotation of the bit such that the roller cone includes a wall contact zone and a bottom contact zone. At least one of the inserts disposed in the wall contact zone has an extension portion terminating in a substantially planar upper surface.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: September 5, 2006
    Assignee: Smith International, Inc.
    Inventors: George B. Witman, Peter Wilson, Scott D. McDonough, Michael A. Siracki
  • Patent number: 6814162
    Abstract: A drill bit, comprising a bit body, a sensor disposed in the bit body, a single journal removably mounted to the bit body, and a roller cone rotatably mounted to the single journal.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: November 9, 2004
    Assignee: Smith International, Inc.
    Inventors: David P. Moran, George B. Witman, IV
  • Patent number: 6719073
    Abstract: A roller cone drill bit is disclosed which includes a bit body adapted to be coupled to a drill string, a bearing journal depending from the bit body and a single roller cone rotatably attached to the journal. The roller cone has a plurality of inserts disposed thereon. In one aspect, the inserts have an extension length of at least 0.6 inches. A roller cone drill bit is disclosed, including a bit body, a bearing journal depending from the bit body, and a single roller cone rotatably attached to the journal. The roller cone has a plurality of inserts disposed thereon. In another aspect, the inserts are arranged such that at most about 20 percent of the inserts are crossed substantially at centerlines thereof by any single plane which contains the axis of the cone axis 10 and which crosses at least two of the inserts.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: April 13, 2004
    Assignee: Smith International, Inc.
    Inventors: Ying Xiang, George B. Witman, IV, Michael A. Siracki
  • Publication number: 20040026124
    Abstract: A drill bit, comprising a bit body, a sensor disposed in the bit body, a single journal removably mounted to the bit body, and a roller cone rotatably mounted to the single journal.
    Type: Application
    Filed: August 9, 2002
    Publication date: February 12, 2004
    Inventors: David P. Moran, George B. Witman
  • Publication number: 20030217867
    Abstract: A roller cone drill bit is disclosed which includes a bit body adapted to be coupled to a drill string, a bearing journal depending from the bit body and a single roller cone rotatably attached to the journal. The roller cone has a plurality of inserts disposed thereon. In one aspect, the inserts have an extension length of at least 0.6 inches. A roller cone drill bit is disclosed, including a bit body, a bearing journal depending from the bit body, and a single roller cone rotatably attached to the journal. The roller cone has a plurality of inserts disposed thereon. In another aspect, the inserts are arranged such that at most about 20 percent of the inserts are crossed substantially at centerlines thereof by any single plane which contains the axis of the cone axis 10 and which crosses at least two of the inserts.
    Type: Application
    Filed: May 21, 2002
    Publication date: November 27, 2003
    Inventors: Ying Xiang, George B. Witman, Michael A. Siracki
  • Publication number: 20030217868
    Abstract: A roller cone drill bit is disclosed which includes a bit body adapted to be coupled to a drill string. A bearing journal depends from the bit body. A single roller cone is rotatably attached to the bearing journal. The roller cone has a plurality of inserts disposed at selected positions about the cone. The journal defines a rotation angle with respect to an axis of rotation of the bit such that the roller cone includes a wall contact zone and a bottom contact zone. At least one of the inserts disposed in the wall contact zone has an extension portion terminating in a substantially planar upper surface.
    Type: Application
    Filed: April 4, 2003
    Publication date: November 27, 2003
    Inventors: George B. Witman, Peter Wilson, Scott D. McDonough, Michael A. Siracki
  • Patent number: 6531305
    Abstract: The invention relates to polypeptides that are sperm-specific forms of the catalytic subunit of cAMP-dependent protein kinases, referred to herein as “Cs polypeptides,” nucleic acid molecules encoding Cs polypeptides, and uses thereof. Cs is found in sperm cells and is related to the cAMP dependent protein kinase C&agr;1.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: March 11, 2003
    Assignee: University of Massachusetts
    Inventors: George B. Witman, Jovenal T. San Agustin, John D. Leszyk
  • Publication number: 20020127620
    Abstract: The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods.
    Type: Application
    Filed: May 24, 2001
    Publication date: September 12, 2002
    Inventors: George B. Witman, Gregory J. Pazour, Joel L. Rosenbaum, Douglas G. Cole