Patents by Inventor George Bobotas

George Bobotas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210205254
    Abstract: Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives thereof, wherein the omega-3 fatty acids comprise eicosapentaenoic acid (EPA; C20:5-n3), docosapentaenoic acid (DPA; C22:5-n3), and docosahexaenoic acid (DHA; C22:6-n3), wherein the ratio of DHA to EPA (DHA:EPA) is less than 1:20, and wherein the ratio of DHA to DPA (DHA:DPA) is less than 2:1 are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: March 18, 2021
    Publication date: July 8, 2021
    Inventors: George BOBOTAS, Abdel Aziz FAWZY
  • Patent number: 10058521
    Abstract: Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives thereof, wherein the omega-3 fatty acids comprise eicosapentaenoic acid (EPA; C20:5-n3), docosapentaenoic acid (DPA; C22:5-n3), and docosahexaenoic acid (DHA; C22:6-n3), wherein the ratio of DHA to EPA (DHA:EPA) is less than 1:20, and wherein the ratio of DHA to DPA (DHA:DPA) is less than 2:1 are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: August 28, 2018
    Assignee: MATINAS BIOPHARMA INC.
    Inventors: George Bobotas, Abdel Aziz Fawzy
  • Patent number: 8906964
    Abstract: The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (LDL) cholesterol, non-HDL cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: December 9, 2014
    Assignee: Matinas BioPharma, Inc.
    Inventors: George Bobotas, Abdel Aziz Fawzy
  • Publication number: 20140322314
    Abstract: Pharmaceutical formulations comprising at least 30% omega-3-fatty acids, salts or derivatives thereof, and one or more additional components selected from the group consisting of: absorption enhancers and adjuvants These formulations have improved pharmacological features, and can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: April 29, 2014
    Publication date: October 30, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: Abdel Aziz Fawzy, George Bobotas
  • Publication number: 20140249226
    Abstract: The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (LDL) cholesterol, non-HDL cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.
    Type: Application
    Filed: May 15, 2014
    Publication date: September 4, 2014
    Applicant: MATINAS BIOPHARMA, INC.
    Inventors: George BOBOTAS, Abdel Aziz FAWZY
  • Patent number: 8784886
    Abstract: Pharmaceutical compositions in unit dose form comprising capsules containing one or more first active pharmaceutical ingredient in a pharmaceutically acceptable vehicle, coated with one or more second active pharmaceutical ingredients, wherein the unit dose form is a pharmaceutical grade finished dosage form, and methods of making and using the same.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: July 22, 2014
    Assignee: GlaxoSmithKline, LLC
    Inventors: Abdel Fawzy, George Bobotas
  • Publication number: 20140194512
    Abstract: Orally administrable composition comprising fatty acids comprising docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA). The compositions can be used for the treatment or prophylaxis of a variety of conditions, including liver-related conditions.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: Abdel Aziz FAWZY, George BOBOTAS, Ihor TERLECKYJ, Roelof RONGEN
  • Publication number: 20140107198
    Abstract: Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives thereof, wherein the omega-3 fatty acids comprise eicosapentaenoic acid (EPA; C20:5-n3), docosapentaenoic acid (DPA; C22:5-n3), and docosahexaenoic acid (DHA; C22:6-n3), wherein the ratio of DHA to EPA (DHA:EPA) is less than 1:20, and wherein the ratio of DHA to DPA (DHA:DPA) is less than 2:1 are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 17, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: George BOBOTAS, Abdel Aziz Fawzy
  • Publication number: 20140107199
    Abstract: Orally administrable composition comprising fatty acids comprising omega-3-fatty acids, salts or derivatives thereof are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: Abdel Aziz FAWZY, George BOBOTAS, Roelof RONGEN
  • Publication number: 20140107206
    Abstract: Orally administrable composition comprising fatty acids comprising omega-3-fatty acids, salts or derivatives thereof are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: Abdel Aziz FAWZY, George BOBOTAS, Ihor TERLECKYJ
  • Publication number: 20140107200
    Abstract: Orally administrable composition comprising fatty acids comprising omega-3-fatty adds, salts or derivatives thereof are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Applicant: MATINAS BIOPHARMA, INC.
    Inventors: ABDEL AZIZ FAWZY, GEORGE BOBOTAS, IHOR TERLECKYJ
  • Publication number: 20140107205
    Abstract: Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives thereof, wherein the omega-3 fatty acids comprise eicosapentaenoic acid (EPA; C20:5-n3), docosapentaenoic acid (DPA; C22:5-n3), and docosahexaenoic acid (DHA; C22:6-n3), wherein the ratio of DHA to EPA (DHA:EPA) is less than 1:20, and wherein the ratio of DHA to DPA (DHA:DPA) is less than 2:1 are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 17, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: George BOBOTAS, Abdel Aziz FAWZY
  • Publication number: 20140100272
    Abstract: The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (LDL) cholesterol, non-HDL cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: George BOBOTAS, Abdel Aziz Fawzy
  • Publication number: 20140100275
    Abstract: The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (LDL) cholesterol, non-HDL cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: George BOBOTAS, Abdel Aziz FAWZY
  • Publication number: 20140100274
    Abstract: The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (LDL) cholesterol, non-HDL cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: George BOBOTAS, Abdel Aziz Fawzy
  • Publication number: 20140100281
    Abstract: Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives thereof, wherein the omega-3 fatty acids comprise eicosapentaenoic acid (EPA; C20:5-n3), docosapentaenoic acid (DPA; C22:5-n3), and docosahexaenoic acid (DHA; C22:6-n3), wherein the ratio of DHA to EPA (DHA:EPA) is less than 1:20, and wherein the ratio of DHA to DPA (DHA:DPA) is less than 2:1 are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Matinas BioPharma, Inc.
    Inventors: George BOBOTAS, Abdel Aziz FAWZY
  • Publication number: 20140100273
    Abstract: The present invention relates to compositions comprising docosapentaenoic acid and methods of reducing lipid parameters, such as triglycerides, total cholesterol, low density lipoprotein (LDL) cholesterol, non-HDL cholesterol, free fatty acids, and other lipids, comprising administration of omega-3 docosapentaenoic acid.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: MATINAS BIOPHARMA, INC.
    Inventors: George BOBOTAS, ABDEL AZIZ FAWZY
  • Publication number: 20140094520
    Abstract: Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives thereof, wherein the omega-3 fatty acids comprise eicosapentaenoic acid (EPA; C20:5-n3), docosapentaenoic acid (DPA; C22:5-n3), and docosahexaenoic acid (DHA; C22:6-n3), wherein the ratio of DHA to EPA (DHA:EPA) is less than 1:20, and wherein the ratio of DHA to DPA (DHA:DPA) is less than 2:1 are provided. These compositions can be used for the treatment or prophylaxis of dyslipidemic, cardiovascular, CNS, inflammatory, and other diseases/conditions or risk factors therefore.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 3, 2014
    Applicant: MATINAS BIOPHARMA, INC.
    Inventors: George BOBOTAS, Abdel Aziz Fawzy
  • Publication number: 20140080889
    Abstract: A method and composition for lipid therapy. In some embodiments, the method comprises providing a subject group having a baseline triglyceride level of 200 to 499 mg/dl and being at or near its low-density lipoprotein cholesterol (LDL-C) level goal, and reducing the triglyceride level and the non-high-density lipoprotein cholesterol (non-HDL-C) level of the subject group as compared to treatment with a 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA) inhibitor alone, by administering to the subject group an effective amount of an HMG CoA inhibitor and a composition comprising omega-3 fatty acids.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: GlaxoSmithKline, LLC
    Inventors: George BOBOTAS, Roelof M. Rongen, Egil Bodd, Hogne Vik
  • Patent number: 8529952
    Abstract: Pharmaceutical compositions comprising micronized fenofibrate, a surfactant and a binding cellulose derivative as a solubilization adjuvant, wherein said compositions contain an amount of fenofibrate greater than or equal to 60% by weight and methods of producing fenofibrate compositions.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: September 10, 2013
    Assignee: Ethypharm
    Inventors: Bruno Criere, Pascal Suplie, Philippe Chenevier, Pascal Oury, Keith S. Rotenberg, George Bobotas