Patents by Inventor George Boyle

George Boyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolidine derivatives and their use as chymase inhibitor
    Publication number: 20040102384
    Abstract: Novel pyrrolidine derivatives, being useful as chymase inhibitor or intermediate for synthesis of the active compounds, which has the formula (I): wherein R1 is cycloalkyl, substituted or unsubstituted phenyl or naphthyl, indanyl, thienyl, furyl, substituted or unsubstituted indolyl, benzofuryl, substituted or unsubstituted benzothienyl, etc.; R2 is H, alkyl, phenyl-lower alkyl, cycloalkyl or cycloalkyl-lower alkyl; R3 is (i) substituted or unsubstituted monocyclic heterocyclic group, (ii) substituted or unsubstituted, benzene- or pyridine-fused heterocyclic group, or (iii) a group (a): R4 and R5 are independently H or OH, but R4 and R5 are not simultaneously H, or both form oxo; n is 0, 1, 2 or 3; or a salt thereof.
    Type: Application
    Filed: February 28, 2003
    Publication date: May 27, 2004
    Inventors: Takashi Deguchi, Ryotaro Shiratake, Fuminori Sato, Buichi Fujitani, Yayoi Honda, Akihiko Kiyoshi, Mitsue Notake, Graham Andrew Showell, Robert George Boyle, Sukhbinder Singh Klair
  • Chk-1 inhibitors
    Publication number: 20040014765
    Abstract: Disclosed are novel inhibitors of Chk-1 and methods of using the same for therapy.
    Type: Application
    Filed: May 28, 2003
    Publication date: January 22, 2004
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Robert George Boyle, Hassan Julien Imogai, Michael Cherry