Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.

Abstract: Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end for aspirating droplets, a singulator to arrange the droplets in single file and to space the single-file droplets from one another, and a detection channel in optical communication with a detector configured to detect a signal from droplets. In some embodiments, the singulator may have a channel junction at which a stream of droplets in single file is combined with a stream of spacing fluid, and a tapered spacing channel extending downstream from the channel junction toward the detection channel. In some embodiments, the fluid transporter may suck droplet-containing fluid and spacing fluid through the detection channel from respective sources. In some embodiments, droplets may be subjected to a disaggregation routine before they are passed through the detection channel.

Abstract: Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end for aspirating droplets, a singulator to arrange the droplets in single file and to space the single-file droplets from one another, and a detection channel in optical communication with a detector configured to detect a signal from droplets. In some embodiments, the singulator may have a channel junction at which a stream of droplets in single file is combined with a stream of spacing fluid, and a tapered spacing channel extending downstream from the channel junction toward the detection channel. In some embodiments, the fluid transporter may suck droplet-containing fluid and spacing fluid through the detection channel from respective sources. In some embodiments, droplets may be subjected to a disaggregation routine before they are passed through the detection channel.

Abstract: Systems and methods for inserting a nanopore into a membrane covering a well are described herein. The membrane can be bowed outwards by establishing an osmotic gradient across the membrane in order to drive fluid into the well, which will increase the amount of fluid in the well and cause the membrane to bow outwards. Nanopore insertion can then be initiated on the bowed membrane.

Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.

Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.

Abstract: Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end for aspirating droplets, a singulator to arrange the droplets in single file and to space the single-file droplets from one another, and a detection channel in optical communication with a detector configured to detect a signal from droplets. In some embodiments, the singulator may have a channel junction at which a stream of droplets in single file is combined with a stream of spacing fluid, and a tapered spacing channel extending downstream from the channel junction toward the detection channel. In some embodiments, the fluid transporter may suck droplet-containing fluid and spacing fluid through the detection channel from respective sources. In some embodiments, droplets may be subjected to a disaggregation routine before they are passed through the detection channel.

Abstract: Systems and methods for detecting and processing signals from particles. In an exemplary method, particles may be passed through a zone of a channel, while the zone is irradiated with light. Interaction of the light with the particles may deflect light and induce photoluminescence. A deflection signal and a photoluminescence signal may be detected from the zone. Particle waveforms may be identified in the deflection signal. At least a subset of the particle waveforms may be double-peak waveforms including a pair of peaks corresponding to a particle entering and exiting the zone. Amplitudes may be obtained from the photoluminescence signal. The amplitudes may correspond to respective particles and their particle waveforms, and at least a subset of the amplitudes may correspond to the double-peak waveforms. Individual particles may be assigned as positive or as negative for an analyte based on the corresponding amplitudes.

Abstract: Systems and methods for detecting and processing signals from particles. In an exemplary method, particles may be passed through a zone of a channel, while the zone is irradiated with light. Interaction of the light with the particles may deflect light and induce photoluminescence. A deflection signal and a photoluminescence signal may be detected from the zone. Particle waveforms may be identified in the deflection signal. At least a subset of the particle waveforms may be double-peak waveforms including a pair of peaks corresponding to a particle entering and exiting the zone. Amplitudes may be obtained from the photoluminescence signal. The amplitudes may correspond to respective particles and their particle waveforms, and at least a subset of the amplitudes may correspond to the double-peak waveforms. Individual particles may be assigned as positive or as negative for an analyte based on the corresponding amplitudes.

Abstract: System, including methods and apparatus, for spacing droplets from each other and for detection of spaced droplets.

Abstract: A grain angle sensor system for measuring grain angle direction of surface fibers of a wood object with respect to at least one of a surface plane direction or a transverse direction, such as a dive angle, or with respect to both the surface plane and transverse direction. The system includes multiple laser diodes and photosensor detectors integrated into an electro-optical assembly that can sequence the firing of the lasers to minimize crosstalk. An exemplary assembly includes an enclosure housing an electronic control board connected to circuit cards containing multiple laser diodes and multiple photosensor detectors.

Abstract: A “Woodprint™” characterization and identification technique employs cameras (16), lighting (14), camera interface hardware (18), a computer (20), and/or image processing software to collect and analyze surface characteristics of pieces of wood (8) to track them through an automated production process in real-time with information that is specific to each wood piece (8), such as what machining is required, its value, and/or its destination. When a wood piece (8) reaches a point in the production process where a decision is required, its unique identity is used to retrieve appropriate information previously determined and assigned to the wood piece (8).

Abstract: A “Woodprint™” characterization and identification technique employs cameras (16), lighting (14), camera interface hardware (18), a computer (20), and/or image processing software to collect and analyze surface characteristics of pieces of wood (8) to track them through an automated production process in real-time with information that is specific to each wood piece (8), such as what machining is required, its value, and/or its destination. When a wood piece (8) reaches a point in the production process where a decision is required, its unique identity is used to retrieve appropriate information previously determined and assigned to the wood piece (8).

Abstract: A “woodprint™” characterization and identification technique unique employs cameras (16), lighting (14), camera interface hardware (18), a computer (20), and/or image processing software to collect and analyze surface characteristics of pieces of wood (8) to track them through an automated production process in real-time with information that is specific to each wood piece (8), such as what machining is required, its value, and/or its destination. When a wood piece (8) reaches a point in the production process where a decision is required, its unique identity is used to retrieve appropriate information previously determined and assigned to the wood piece (8).

Abstract: An apparatus for reading information marks comprising a strobe light activating or reflecting information marks manually placed on objects or wood products. A camera is used for reading the marks. One or more detectors are used to recognize marks and color. A central processing unit is used to process, solve and interpret character and color recognition. A photo-electric eye or a signal from a control device is used to time the strobe and detector. The information contained in the marks is fed directly to the control system and may be used to generate reports.