Patents by Inventor George Collins

George Collins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200087621
    Abstract: Sodium cellulose sulfate (NaCS) is employed as a novel GAG mimetic. Schwann cells (SCs) could be used in combination with a scaffold because the SCs can secrete neurotrophic factors stimulating neuron survival and extension of axons. Furthermore, the conduit may be used alone or combination with Schwann cells for spinal cord repair. In addition, the conduit also can be used for peripheral nerve repair. Also described herein are compositions and methods useful for promoting the growth and/or differentiation and/or repair of a cell and/or tissue in the peripheral nervous system, central nervous system, and specifically the spinal cord. In certain aspects, the present disclosure includes a scaffold supporting and promoting growth, differentiation, and/or regeneration and repair. The scaffold in one embodiment closely mimics the natural extracellular matrix (ECM) of the spinal cord.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 19, 2020
    Applicants: New Jersey Institute of Technology, University of Miami
    Inventors: Treena Lynne Arinzeh, Roseline Menezes, George Collins, Sharareh Hashemi, Martin Oudega
  • Publication number: 20200038542
    Abstract: A method is revealed that teaches that a UV or near-UV lighting source inside a lighting fixture can be used to fulfil two functions; (1) First, to disinfect room air of bioaerosols and remove certain air-borne chemicals; and then (2) To excite white or other color phosphor compounds, so that the final output of the lighting fixture is that of visible non-UV light. The method results in a minimal increase in operating energy costs over that of a standard LED light fixture, but with the added benefit of providing air disinfection and purification.
    Type: Application
    Filed: August 6, 2018
    Publication date: February 6, 2020
    Applicant: Skizukesa Technologies LLC
    Inventors: Philip George Franklin, Jeffery Jay Collins
  • Patent number: 10420856
    Abstract: Provided is an electroactive structure and method for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: September 24, 2019
    Inventors: Treena Arinzeh, George Collins, Yee-Shuan Lee
  • Patent number: 10415454
    Abstract: A control system is provided for thermal management of an aftertreatment device in an engine that is provided in an enclosure. The engine has a cooling fan that is operable in a first direction to cool said engine. The fan is also operable in a reverse direction opposite to the first direction. The control system includes a first temperature sensor that measures a temperature of the engine or the enclosure. The control system further includes a second temperature sensor that measures a temperature of the aftertreatment device. The control system also includes a processor that is coupled to the first and second temperature sensors. The processor is configured to issue control signals, based on whether regeneration is required by the aftertreatment device or not, for selectively controlling a direction of operation associated with the cooling fan.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: September 17, 2019
    Assignee: Perkins Engines Company Limited
    Inventors: Martin George Constantine, Ross Daniel Collins
  • Publication number: 20190196696
    Abstract: A social media platform stores immersive videos and embedded affordances for each immersive video. Each embedded affordance has a temporal location, a spatial location, and a corresponding reward. A viewer selects and plays a first immersive video. While playing the first stored immersive video, the viewer navigates to different spatial portions of the first immersive video using a spatial visibility window. The viewer activates a first embedded affordance of the first immersive video according to the spatial and temporal location of the first embedded affordance. In response, the platform initiates the reward corresponding to the first embedded affordance. The reward includes a reward token deposited into an account corresponding to the viewer. The viewer later uses a redemption user interface to redeem a plurality of reward tokens from the account (including the deposited reward token) for a single aggregated reward.
    Type: Application
    Filed: March 5, 2019
    Publication date: June 27, 2019
    Inventors: Dipak Mahendra Patel, Arlene Joy Ganancial Santos, Scott Riley Collins, Bryan Daniel Bor, Adam Mark Dubov, Timothy George Harrington, II, Jason Sperske
  • Publication number: 20190175354
    Abstract: A prosthesis assembly is provided that includes a base member that has a helical structure and a cylindrical member opposite the helical structure. The cylindrical member is configured for direct connection with a reverse insert of a reverse shoulder assembly. The cylindrical member is configured for direct connection with a reverse insert spacer in some embodiments. The reverse insert can be inserted into a space defined at least in part by a wall of the cylindrical member and an inferior wall of the of the base member. The helical structure extends between a first end and a second end. The base member also can include one or more pathways. The pathway(s) is accessible from the second end and is directed toward the first end through the helical structure. The pathway is located inward of an outer periphery of the helical structure, e.g., adjacent to an inner periphery of the helical structure. The pathway extends in a space between successive portions of the helical structure.
    Type: Application
    Filed: December 4, 2018
    Publication date: June 13, 2019
    Inventors: Kevin P. Knox, Shawn M. Gargac, Austin Wyatt Mutchler, Philippe Collin, George S. Athwal
  • Publication number: 20190134263
    Abstract: The present invention relates to a vascularized three dimensional construct for thick tissue, a process for making the construct and to the use of the construct in tissue regeneration and repair and in drug development. The three-dimensional (3-D) tissue technology is used to generate vascularized, biomimetic tissue models in vitro utilizing a biodegradable nanofiber scaffold. The culture system allows the maintenance of long-term survival and function of liver and heart cells. The system utilizes a novel approach to generate structures that mimic in vivo tissue architecture. The system provides a microenvironment for forming 3-D microvascular networks within the nanofiber scaffolds.
    Type: Application
    Filed: March 1, 2012
    Publication date: May 9, 2019
    Inventors: Cheul H Cho, Ali Hussain, George Collins, Divya Ranendran
  • Publication number: 20180363998
    Abstract: The present invention provides a firearm component having improved grippability for use with a firearm, such as a pistol, revolver, or other suitable handgun, and a method for manufacturing same. The firearm component hereof includes an abrasive material deposited onto at least a portion thereof. The abrasive material is selected from the group consisting of natural diamond, synthetic diamond, cubic boron nitride, sapphire, and carbide. Preferably, the abrasive material is either natural or synthetic diamond ground down to micron-sized diamond particulates. The diamond particulates are then deposited onto at least a portion of the firearm component by way of electroplating, electroless plating, or brazing.
    Type: Application
    Filed: June 19, 2017
    Publication date: December 20, 2018
    Inventor: George Collins
  • Publication number: 20180221453
    Abstract: A scaffold for promoting cartilage formation is provided that includes a crosslinked electrospun fiber, wherein the crosslinked electrospun fiber consists essentially of crosslinked gelatin. The crosslinked electrospun fiber is generally crosslinked with a crosslinker, and the crosslinker may be diisosorbide bisepoxide. The crosslinked electrospun fiber may be crosslinked by adding a crosslinker to a solution of gelatin at a desired concentration. The electrospun fiber may advantageously remain intact for 18 days or longer upon being immersed in an aqueous solution. A composition for promoting cartilage formation is also provided that includes the disclosed scaffold and a mesenchymal stem cell (MSC). The disclosed scaffold may include a crosslinked electrospun fiber that includes gelatin and sodium cellulose sulfate (NaCS), e.g., in an amount of up to 5% by weight of the amount of gelatin.
    Type: Application
    Filed: April 6, 2018
    Publication date: August 9, 2018
    Applicant: New Jersey Institute of Technology
    Inventors: Tamilvizhi Muthalagu, George Collins, Treena L. Arinzeh
  • Publication number: 20170340711
    Abstract: A scaffold for promoting cartilage formation is provided that includes a crosslinked electrospun fiber, wherein the crosslinked electrospun fiber consists essentially of crosslinked gelatin. The crosslinked electrospun fiber is generally crosslinked with a crosslinker, and the crosslinker may be diisosorbide bisepoxide. The crosslinked electrospun fiber may be crosslinked by adding a crosslinker to a solution of gelatin at a desired concentration. The electrospun fiber may advantageously remain intact for 18 days or longer upon being immersed in an aqueous solution. A composition for promoting cartilage formation is also provided that includes the disclosed scaffold and a mesenchymal stem cell (MSC). The disclosed scaffold may include a crosslinked electrospun fiber that includes gelatin and sodium cellulose sulfate (NaCS), e.g., in an amount of up to 5% by weight of the amount of gelatin.
    Type: Application
    Filed: August 10, 2017
    Publication date: November 30, 2017
    Applicant: New Jersey Institute of Technology
    Inventors: Tamilvizhi Muthalagu, George Collins, Treena L. Arinzeh
  • Patent number: 9771557
    Abstract: Provided is an electroactive structure for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: September 26, 2017
    Assignee: New Jersey Institute of Technology
    Inventors: Treena Arinzeh, George Collins, Yee-Shuan Lee
  • Patent number: 9676045
    Abstract: Electrodes, components, apparatuses, and methods for electrochemical machining (ECM) are disclosed. ECM may be employed to provide burr-free or substantially burr-free ECM of electrically-conductive workpieces (e.g. shrouds). As one non-limiting example, the electrically-conductive workpiece may be a shroud that is used as an electrical component in electronics boards. While the ECM components, apparatuses, and methods disclosed herein reduce burrs, ECM can provide imprecise machining and cause stray erosions to occur in the machined electrically-conductive workpiece. In this regard, the electrodes, components, apparatuses, and methods for ECM disclosed herein provide features that allow for precise machining of the machined electrically-conductive workpiece and also allow avoidance of stray erosions in the machined electrically-conductive workpiece.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: June 13, 2017
    Assignee: Corning Optical Communications RF LLC
    Inventors: Terry George Collins, Dominick John Forenz, Mark Lee Humphrey
  • Patent number: 9643157
    Abstract: A hydrogel composition is provided that includes crosslinked dextran and dextran sulfate. The hydrogel composition may be included in a matrix that includes an osmotically active material immobilized in the matrix. The hydrogel composition can be combined into superabsorbent preparations that are capable of adsorbing large amounts of water. The superabsorbent preparations have advantages in the use of absorbent materials for physiological fluids, such as diapers, incontinence products, wound dressings and the like, as well as agricultural and environmental applications. In addition, biodegradable superabsorbents of the invention can be prepared.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: May 9, 2017
    Assignee: New Jersey Institute of Technology
    Inventors: Bhavita Joshi, George Collins, Treena Arinzeh
  • Publication number: 20170051251
    Abstract: Provided is an electroactive structure for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
    Type: Application
    Filed: April 21, 2016
    Publication date: February 23, 2017
    Applicant: New Jersey Institute of Technology
    Inventors: Treena Arinzeh, George Collins, Yee-Shuan Lee
  • Publication number: 20170050172
    Abstract: A hydrogel composition is provided that includes crosslinked dextran and dextran sulfate. The hydrogel composition may be included in a matrix that includes an osmotically active material immobilized in the matrix. The hydrogel composition can be combined into superabsorbent preparations that are capable of adsorbing large amounts of water. The superabsorbent preparations have advantages in the use of absorbent materials for physiological fluids, such as diapers, incontinence products, wound dressings and the like, as well as agricultural and environmental applications. In addition, biodegradable superabsorbents of the invention can be prepared.
    Type: Application
    Filed: November 9, 2016
    Publication date: February 23, 2017
    Applicant: New Jersey Institute of Technology
    Inventors: Bhavita Joshi, George Collins, Treena Arinzeh
  • Publication number: 20160354515
    Abstract: Provided is an electroactive structure and method for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
    Type: Application
    Filed: August 22, 2016
    Publication date: December 8, 2016
    Applicant: New Jersey Institute of Technology
    Inventors: Treena Arinzeh, George Collins, Yee-Shuan Lee
  • Patent number: 9504987
    Abstract: A hydrogel matrix and an osmotically active material immobilized in the matrix can be combined into superabsorbent preparations that are capable of adsorbing large amounts of water. The superabsorbent preparations of the invention have advantages in the use of absorbent materials for physiological fluids, such as diapers, incontinence products, wound dressings and the like, as well as agricultural and environmental applications. In addition, biodegradable superabsorbents of the invention can be prepared.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: November 29, 2016
    Assignee: New Jersey Institute of Technology
    Inventors: Bhavita Joshi, George Collins, Treena Arinzeh
  • Patent number: 9476026
    Abstract: Provided is an electroactive structure and method for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: October 25, 2016
    Assignee: New Jersey Institute of Technology
    Inventors: Treena Arinzeh, George Collins, Yee-Shuan Lee
  • Patent number: 9334476
    Abstract: Provided is an electroactive structure for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: May 10, 2016
    Assignee: New Jersey Institute of Technology
    Inventors: Treena Arinzeh, George Collins, Yee-Shuan Lee
  • Patent number: 9192655
    Abstract: The embodiments and examples provided herein are put forth so as to provide those of ordinary skill in the art with a complete disclosure and description of how to make and use the present invention, and are not intended to limit the present invention relates to compositions and methods of preparing a hydrogel comprising a water soluble cellulose compound, as well as preparing a three-dimensional matrix of micron sized electrospun fibers, wherein the electrospun fibers are formed from a electrospun composite comprising a water soluble cellulose compound. The matrix provides a scaffold supporting and promoting cartilage regeneration and repair.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: November 24, 2015
    Assignee: New Jersey Institute of Technology
    Inventors: Treena Arinzeh, George Collins, Bruno Mantilla