Patents by Inventor George D. Corey

George D. Corey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6958148
    Abstract: Methods, products and kits are provided for attaching agents to a body tissue surface via microparticles using endogenous or exogenous transglutaminase. The microparticles have surface available transglutaminase substrate reactive groups. In an embodiment, the groups are part of a polymer containing at least two contiguous linked lysines or at least three contiguous linked glutamines.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: October 25, 2005
    Assignee: Pericor Science, Inc.
    Inventors: Howard Green, Bruce J. Compton, George D. Corey, Philippe Djian
  • Patent number: 6709869
    Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are also optionally provided having system informatics and data acquisition, analysis and storage and retrieval informatics encoded on the surface of the disk opposite to the surface containing the fluidic components. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: March 23, 2004
    Assignee: Tecan Trading AG
    Inventors: Alec Mian, Stephen G. Kieffer-Higgins, George D. Corey
  • Publication number: 20020137218
    Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are also optionally provided having system informatics and data acquisition, analysis and storage and retrieval informatics encoded on the surface of the disk opposite to the surface containing the fluidic components. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.
    Type: Application
    Filed: November 20, 2001
    Publication date: September 26, 2002
    Inventors: Alec Mian, Stephen G. Kieffer-Higgins, George D. Corey
  • Publication number: 20010055812
    Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are also provided having system informatics and data acquisition, analysis and storage and retrieval informatics encoded on the surface of the disk opposite to the surface containing the fluidic components. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.
    Type: Application
    Filed: December 5, 1996
    Publication date: December 27, 2001
    Inventors: ALEC MIAN, STEPHEN G. KIEFFER-HIGGINS, GEORGE D. COREY
  • Patent number: 6319469
    Abstract: This invention relates to methods and apparatus for performing microanalytic and microsynthetic analysis and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels. The microsystem platforms of the invention are also optionally provided having system informatics and data acquisition, analysis and storage and retrieval informatics encoded on the surface of the disk opposite to the surface containing the fluidic components. Methods specific for the apparatus of the invention for performing any of a wide variety of microanalytical or microsynthetic processes are provided.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: November 20, 2001
    Assignee: Silicon Valley Bank
    Inventors: Alec Mian, Stephen G. Kieffer-Higgins, George D. Corey
  • Patent number: 6267957
    Abstract: Methods, products and kits are provided for attaching agents to tissue with a linking molecule in the presence of transglutaminase. The linking molecule and/or agent is a substrate of transglutaminase. The agent can be a nonprotein or an enzyme such as cholinesterase or phosphodiesterase. The transglutaminase may be exogenously added or be endogenous in tissue. In specific embodiments, the linking molecule contains at least two contiguous linked glutamines or at least three contiguous linked lysines. A conjugate of the agent and the linking molecule may be applied to tissue, and in the presence of transglutaminase covalently bonded to the tissue via the linking molecule. A complementary linking molecule rich in lysines may be first attached to the tissue in the presence of transglutaminase, and then covalently bonded to a glutamine-containing linking molecule of the conjugate in the presence of transglutaminase.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: July 31, 2001
    Inventors: Howard Green, George D. Corey, Bruce J. Compton, Philippe Dijan