Patents by Inventor George D. Hiler, II

George D. Hiler, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5149642
    Abstract: A process for the selective hydrolysis of triglycerides to mixtures of 1,3 or 2,3-diacyl glycerides and 2-acyl glycerides is disclosed. This process uses an alkyl alcohol selected from the group consisting of 2-methyl-2-propanol, 2-butanol and the primary, secondary or tertiary branched or straight chain alkyl alcohols having from 5 to 8 carbon atoms, and mixtures thereof, an aqueous buffer system and a 1,3-lipase. The 2-acyl glycerides in the mixture are esterified to make stereospecific 1,2-diacyl glycerides or 2,3-diacyl glycerides with acid anhydrides and a lipase catalyst. Under the reaction conditions, there is little rearrangement of the diacyl glycerides in the mixture and less than 20% triglyceride is formed. Stereospecific 1,2,4-triglycerides can be made from these materials by standard esterification reactions under conditions which control rearrangement.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: September 22, 1992
    Assignee: The Procter & Gamble Company
    Inventors: Adam W. Mazur, George D. Hiler, II, Magda El-Nokaly
  • Patent number: 5137660
    Abstract: A process for the selective esterification of glycerol and 1-glyceryl derivatives to 1,3-disubstituted glycerides is disclosed. This process uses a water immiscible solvent, either a hydrocarbon or halogenated hydrocarbon, a 1,3-lipase and fatty acid anhydrides. This reaction mixture selectively esterifies the primary alcohol groups of glycerol or glycerol derivatives. The preferred derivatives of glycerol are alkyl ethers, alkyl phosphates, phospholipids, alkyl and diaklyl phosphates, and sugar glycosides.
    Type: Grant
    Filed: March 15, 1991
    Date of Patent: August 11, 1992
    Assignee: The Procter & Gamble Company
    Inventors: Adam W. Mazur, George D. Hiler, II
  • Patent number: 5116745
    Abstract: A process for the selective hydrolysis of triglyderides to 2-acyl glycerides is disclosed. This process uses a primary lower alkyl alcohol selected from the group consisting of methanol, the primary butanols and the primary pentanols and 2-butanol, an aqueous buffer system and a 1,3-lipase. The 2-acylmonglycerides can be used to make stereospecific 1,2-diacyl glycerides or 2,3-diacyl glycerides through esterification with acid anhydrides and 1,3-lipase catalysis. Stereospecific 1,2,3-triglycerides can be made from these materials by standard esterification reactions under conditions which control rearrangement.
    Type: Grant
    Filed: April 19, 1990
    Date of Patent: May 26, 1992
    Assignee: The Procter & Gamble Company
    Inventors: Adam W. Mazur, George D. Hiler, II, Magda El-Nokaly
  • Patent number: 5104797
    Abstract: Processes of the present invention provide economical methods for preparing derivatives 5-C-hydroxymethyl-D-aldohexose and their bicyclic anhydro tautomeric forms. The 5-C-hydroxymethylation process comprises an enzymic oxidation reaction followed by a condenation reaction with formaldehyde.
    Type: Grant
    Filed: April 17, 1989
    Date of Patent: April 14, 1992
    Assignee: The Procter & Gamble Company
    Inventors: Adam W. Mazur, George D. Hiler, II, Gordon K. Stipp, Bernard W. Kluesener