Patents by Inventor George Detre

George Detre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topically active steroidal anti-inflammatory agents
    Patent number: 4910192
    Abstract: Introduction of a C-12 substituent and especially a .beta. C-12 substituent into glucocorticoids improves their usefulness as topical antiinflammatories by increasing their topical activity relative to their systemic activity, thus reducing systemic side effects such as adrenal suppression.
    Type: Grant
    Filed: December 4, 1987
    Date of Patent: March 20, 1990
    Assignee: SRI International
    Inventors: Mitchell A. Avery, Masato Tanabe, Dennis Yasuda, George Detre
  • 17 a .beta.-hydroxy-7 .alpha.-methyl-d-homo-19-norandrost-4,16-diene-3-one and the 17-esters thereof: methods of preparation and uses
    Patent number: 4788218
    Abstract: Novel compounds having the general formula: ##STR1## wherein: R.sup.1 is hydrogen or an acyl substituent of the formula:--(C.dbd.O)--R.sup.2wherein:R.sup.2 is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkylene, haloalkyl, aryl, haloaryl or arylalkylene are described. These compounds have both gonadotropic and antigonadotropic properties depending upon the dosage level, and are therefore useful in therapy in the control of male fertility in mammals, particularly in human beings. These compounds combine gonadotropic, antigonadotropic and androgenic properties in the same compound. Their use with LHRH antagonists on male fertility control is also disclosed.
    Type: Grant
    Filed: April 28, 1986
    Date of Patent: November 29, 1988
    Assignee: SRI International
    Inventors: Masato Tanabe, David F. Crowe, George Detre, Peters, Richard H., Mitchell A.g34 Avery
  • 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity
    Patent number: 3946052
    Abstract: 19-Norpregna-1,3,5(10)-trien-3-ol and loweralkyl homologs thereof wherein the alkyl group attached in the 17.beta. position contains from 2 to 7 carbon atoms. Said compounds, along with the corresponding known 17.beta.-methyl derivative, are found to have antifertility activity, and particularly postcoital antifertility activity, along with very low estrogenic activity, when administered orally to mammals.
    Type: Grant
    Filed: June 16, 1975
    Date of Patent: March 23, 1976
    Assignee: Stanford Research Institute
    Inventors: David F. Crowe, Richard H. Peters, Masato Tanabe, George Detre