Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).

Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).

Abstract: The present invention relates to a cooling arrangement in which a fractal passage network is provided incorporating several passage stages. Each passage stage 4, 5, 6, 7 has substantially the same passage cross-section for consistency with other passage stages to facilitate flow pressure control across the fractal passage network. Normally, the length of passages in each passage stage are also specifically determined in order to achieve a consistent flow pressure control. The arrangement is particularly utilized with regard to cooling within turbine engine components such as blade aerofoils.

Abstract: The invention provides compositions formulated to attract fish, comprising at least one human female pheromone such as trimethylamine, pyrroline and salts thereof, steroids of the androstene family such as 5-alpha-androst-16-en-3-?-ol, heterocyclic compounds such as indole and skatole and alkanoic acid compounds such as 4-methyloctanoic acid. Compositions can be formulated as liquids for direct application to bait, hooks or flies. Plastic bait can be manufactured including the composition. The composition can be used to attract fish by fishermen and anglers or to guide fish into paths to enable them to cross dams.

Abstract: A treatment for female sexual dysfunction by the provision of at least one dopamine mimetic odorant, the odorant being capable of causing a physiological effect in, or from, the human brain which ameliorates the dysfunction, particularly Hypoactive Sexual Desire Disorder (HSDD), and delivery systems therefore.

Abstract: The present invention is concerned with pharmaceutical compositions comprising a mixture of amlodipine enantiomers, which compositions have both anti-hypertensive and additional cardiovascular properties derived respectively from their calcium channel-blocking activity and their ability to release vascular nitric oxide (NO).

Abstract: The present invention is concerned with pharmaceutical compositions comprising a mixture of amlodipine enantiomers, which compositions have both anti-hypertensive and additional cardiovascular properties derived respectively from their calcium channel-blocking activity and their ability to release vascular nitric oxide (NO).

Abstract: A vane for directing hot gases of a gas turbine engine and comprising at least one platform and a hollow aerofoil portion having an air entry tube extending spanwise therein, the tube being provided with a plurality of apertures, the size and the spacing therebetween being chosen to cause cooling fluid to impinge on the interior surface of the aerofoil portion in the form of a plurality of jets. A plurality of columnar projections extend between the interior surface of the aerofoil portion and the exterior of the air entry tube, each projection being positioned directly upstream of one of the apertures in the air entry tube with respect to the general flow of impinged fluid in the space between the interior surface of the aerofoil portion and the exterior of the air entry tube.