Patents by Inventor George Douglas Leikauf

George Douglas Leikauf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protection from chemical-induced acute lung injury
    Patent number: 9492408
    Abstract: Methods are provided herein for treating an individual having a disease, disorder or condition affecting the lungs, wherein said disease, disorder, or condition of the lung is an acute lung injury. In specific embodiments, the acute lung injury is chemical induced acute lung injury (CIALI). In some embodiments, the methods are provided for treating or protecting a subject from chemical induced acute lung injury that include administering to the subject a therapeutically effective amount of a phosphatase located on chromosome 10 (PTEN) inhibitor such as N(9,10-dioxo-9,10-di-hydrophenanthren-2-yl)pivalamide (SF1670). In some embodiments, the method products a subject from CAILI or reduces CAILI that results from a subsequent exposure to a chemical that induces chemical induced acute lung injury.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: November 15, 2016
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventor: George Douglas Leikauf
  • PROTECTION FROM CHEMICAL-INDUCED ACUTE LUNG INJURY
    Publication number: 20150119468
    Abstract: Methods are provided herein for treating an individual having a disease, disorder or condition affecting the lungs, wherein said disease, disorder, or condition of the lung is an acute lung injury. In specific embodiments, the acute lung injury is chemical induced acute lung injury (CIALI). In some embodiments, the methods are provided for treating or protecting a subject from chemical induced acute lung injury that include administering to the subject a therapeutically effective amount of a phosphatase located on chromosome 10 (PTEN) inhibitor such as N(9,10-dioxo-9,10-di-hydrophenanthren-2-yl)pivalamide (SF1670). In some embodiments, the method products a subject from CAILI or reduces CAILI that results from a subsequent exposure to a chemical that induces chemical induced acute lung injury.
    Type: Application
    Filed: October 23, 2014
    Publication date: April 30, 2015
    Applicant: University of Pittsburgh–Of the Commonwealth System of Higher Education
    Inventor: George Douglas Leikauf