Patents by Inventor George E. Schwab

George E. Schwab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6083499
    Abstract: The subject invention concerns new classes of pesticidal toxins and the polynucleotide sequences which encode these toxins. Also described are novel pesticidal isolates of Bacillus thuringiensis.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: July 4, 2000
    Assignee: Mycogen Corporation
    Inventors: Kenneth E. Narva, H. Ernest Schnepf, Mark Knuth, Michael R. Pollard, Guy Cardineau, George E. Schwab
  • Patent number: 6077937
    Abstract: Novel Bacillus thuringiensis toxins with hymenopteran activity are described.
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: June 20, 2000
    Assignee: Mycogen Corporation
    Inventors: Jewel M. Payne, M. Keith Kennedy, John Brookes Randall, Henry Meier, Heidi Jane Uick, Luis Foncerrada, H. Ernest Schnepf, George E. Schwab, Jenny Fu
  • Patent number: 6051556
    Abstract: The invention concerns novel hybrid pesticidal toxins. These toxins are expressed as the fusion protein of a chimeric gene. Specifically exemplified is a novel B.t. hybrid toxin. These novel toxins have increased toxicity against target pests. The invention also concerns a process for preparing a hybrid virus having an altered insect host range.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: April 18, 2000
    Assignee: Mycogen Corporation
    Inventors: Edward R. Wilcox, David L. Edwards, George E. Schwab, Mark Thompson, Paul Culver
  • Patent number: 5985267
    Abstract: Disclosed and claimed are novel Bacillus thuringiensis isolates which have lepidopteran activity. Thus, these isolates, or mutants thereof, can be used to control such insect pests. Further, genes encoding novel .delta.-endotoxins can be removed from the isolates and transferred to other host microbes, or plants. Expression of the .delta.-endotoxins in such hosts results in the control of susceptible insect pests in the environment of such hosts.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: November 16, 1999
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick, Kenneth E. Narva, H. Ernest Schnepf, George E. Schwab
  • Patent number: 5932209
    Abstract: An improved Bacillus thuringiensis (B.t.) delta-endotoxin is created by the modification of the gene encoding the toxin. The toxicity of a B.t. toxin was improved by replacing the native protoxin segment with an alternate protoxin segment by constructing a chimeric toxin gene.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: August 3, 1999
    Assignee: Mycogen Corporation
    Inventors: Mark Thompson, George E. Schwab, H. Ernest Schnepf, Brian Stockhoff
  • Patent number: 5840554
    Abstract: Bacillus thuringiensis endotoxin expression in Pseudomonads can be improved by modifying the gene encoding the Bacillus thuringiensis endotoxin. Chimeric genes are created by replacing the segment of the Bacillus thuringiensis gene encoding a native protoxin with a segment encoding a different protoxin. Exemplified herein is the cryIF/cryI(b) chimera wherein the native cryIF protoxin segment has been substituted by the cryIA(b) protoxin segment, to yield improved expression of the cryIF toxin in Pseudomonads. The invention also concerns novel genes and plasmids.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: November 24, 1998
    Assignee: Mycogen Corporation
    Inventors: Mark Thompson, George E. Schwab
  • Patent number: 5827514
    Abstract: Disclosed are compositions and processes for controlling lepidopteran pests. These compositions comprise synergistic combinations of a CryIF chimeric and CryIA(c) chimeric Bacillus thuringiensis .delta.-endotoxin. These compositions have been found to exhibit excellent activity against lepidopteran pests.
    Type: Grant
    Filed: February 8, 1996
    Date of Patent: October 27, 1998
    Assignee: Mycogen Corporation
    Inventors: Gregory A. Bradfisch, Mark Thompson, George E. Schwab
  • Patent number: 5824792
    Abstract: Novel Bacillus thuringiensis toxins with hymenopteran activity are described.
    Type: Grant
    Filed: March 6, 1996
    Date of Patent: October 20, 1998
    Assignee: Mycogen Corporation
    Inventors: Jewel M. Payne, M. Keith Kennedy, John Brookes Randall, Henry Meier, Heidi Jane Uick, Luis Foncerrada, H. Ernest Schnepf, George E. Schwab, Jenny Fu
  • Patent number: 5753249
    Abstract: The subject invention concerns methods and compositions for the selective control of pests. The method involves the administration of compounds which act on ecdysteroids or their derivatives or precursors. In a preferred embodiment, plants are transformed to express ecdysone oxidase which controls pests which feed on the transformed plants.
    Type: Grant
    Filed: December 8, 1995
    Date of Patent: May 19, 1998
    Assignee: Mycogen Corporation
    Inventor: George E. Schwab
  • Patent number: 5753492
    Abstract: This invention concerns genes or gene fragments which have been cloned from novel Bacillus thuringiensis isolates which have nematicidal activity. These genes or gene fragments can be used to transform suitable hosts for controlling nematodes.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: May 19, 1998
    Assignee: Mycogen Corporation
    Inventors: H. Ernest Schnepf, George E. Schwab, Jewel Payne, Kenneth E. Narva, Luis Foncerrada
  • Patent number: 5686069
    Abstract: Disclosed and claimed are novel Bacillus thuringiensis isolates which have lepidopteran activity. Thus, these isolates, or mutants thereof, can be used to control such insect pests. Further, genes encoding novel .delta.-endotoxins can be removed from the isolates and transferred to other host microbes, or plants. Expression of the .delta.-endotoxins in such hosts results in the control of susceptible insect pests in the environment of such hosts.
    Type: Grant
    Filed: August 15, 1994
    Date of Patent: November 11, 1997
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick, Kenneth E. Narva, H. Ernest Schnepf, George E. Schwab
  • Patent number: 5616495
    Abstract: Novel Bacillus thuringiensis isolates with hymenopteran activity are described. Also described are toxins having the advantageous hymenopteran activity.This invention further concerns genes or gene fragments which have been cloned from the novel Bacillus thuringiensis isolates which have formicidal activity. These genes or gene fragments can be used to transform suitable hosts for controlling ants.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: April 1, 1997
    Assignee: Mycogen Corporation
    Inventors: Jewel M. Payne, M. Keith Kennedy, John B. Randall, Henry Meier, Heidi J. Uick, Luis Foncerrada, Harry E. Schnepf, George E. Schwab
  • Patent number: 5596071
    Abstract: Novel Bacillus thuringiensis toxins with hymenopteran activity are described.
    Type: Grant
    Filed: November 24, 1993
    Date of Patent: January 21, 1997
    Assignee: Mycogen Corporation
    Inventors: Jewel M. Payne, M. Keith Kennedy, John B. Randall, Henry Meier, Heidi J. Uick, Luis Foncerrada, H. Ernest Schnepf, George E. Schwab, Jenny Fu
  • Patent number: 5593881
    Abstract: An improved Bacillus thuringiensis (B.t.) delta-endotoxin is created by the modification of the gene encoding the toxin. The toxicity of a B.t. toxin was improved by replacing the native protoxin segment with an alternate protoxin segment by constructing a chimeric toxin gene.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: January 14, 1997
    Assignee: Mycogen Corporation
    Inventors: Mark Thompson, George E. Schwab, H. Ernest Schnepf, Brian Stockhoff
  • Patent number: 5527883
    Abstract: Bacillus thuringiensis endotoxin expression in Pseudomonads can be improved by modifying the gene encoding the Bacillus thuringiensis endotoxin. Chimeric genes are created by replacing the segment of the Bacillus thuringiensis gene encoding a native protoxin with a segment encoding a different protoxin. Exemplified herein is the cryIF/cryI(b) chimera wherein the native cryIF protoxin segment has been substituted by the cryIA(b) protoxin segment, to yield improved expression of the cryIF toxin in Pseudomonads. The invention also concerns novel genes and plasmids.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: June 18, 1996
    Assignee: Mycogen Corporation
    Inventors: Mark Thompson, George E. Schwab
  • Patent number: 5508264
    Abstract: Disclosed are compositions and processes for controlling lepidopteran pests. These compositions comprise synergistic combinations of a CryIF chimeric and CryIA(c) chimeric Bacillus thuringiensis .delta.-endotoxin. These compositions have been found to exhibit excellent activity against lepidopteran pests.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: April 16, 1996
    Assignee: Mycogen Corporation
    Inventors: Gregory A. Bradfisch, Mark Thompson, George E. Schwab
  • Patent number: 5468636
    Abstract: The subject invention concerns Bacillus thuringiensis isolates designated B.t. PS157C1, B.t. PS86A1, and B.t. PS75J1, which are active against aphid pests. Thus, these isolates, or variants thereof, can be used to control such pests. Further, genes encoding novel .delta.-endotoxins can be removed from these isolates and transferred to other host microbes, or plants. Expression of the .delta.-endotoxins in microbe hosts results in the control of aphid pests, whereas transformed plants become resistant to aphid pests.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: November 21, 1995
    Assignee: Mycogen Corporation
    Inventors: Jewel M. Payne, Raymond J. C. Cannon, H. Ernest Schnepf, George E. Schwab
  • Patent number: 5439881
    Abstract: This invention concerns genes or gene fragments which have been cloned from novel Bacillus thuringiensis isolates which have nematicidal activity. These genes or gene fragments can be used to transform suitable hosts for controlling nematodes.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: August 8, 1995
    Assignee: Mycogen Corporation
    Inventors: Kenneth E. Narva, George E. Schwab, Jewel M. Payne
  • Patent number: 5430137
    Abstract: This invention concerns novel gene probes which can be used to identify DNA from Bacillus thuringiensis microbes which encode protein endotoxins. The invention probes greatly facilitate the search for useful microbes hosting genes which encode toxins.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: July 4, 1995
    Assignee: Mycogen Corporation
    Inventors: Frank H. Gaertner, August J. Sick, Mark Thompson, H. Ernest Schnepf, George E. Schwab, Kenneth E. Narva
  • Patent number: 5426049
    Abstract: Nematicidal .delta.-endotoxin encoding genes have been cloned from a novel Bacillus thuringiensis isolate known as B.t. PS17. These novel genes, designated B.t. PS17a, B.t. PS17b, B.t. PS17d, and B.t. PS17e, can be transferred to various microbial and plant hosts via known techniques. In the microbial or plant host, one or more of the genes of the invention can be used to express the novel nematicidal toxins to control susceptible nematodes.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: June 20, 1995
    Assignee: Mycogen Corporation
    Inventors: August J. Sick, George E. Schwab, Jewel M. Payne