Abstract: Liquid pharmaceutical liquid compositions that are orally administered and methods for their use by administration to the lungs for multifunctional treatment of lung and respiratory diseases.

Abstract: Methods of use and pharmaceutical liquid compositions that are orally administered to the lungs through vaporization and aerosol generating devices providing multifunctional treatment for lung and respiratory diseases are presented.

Abstract: This disclosure relates to multifunctional formulations, methods of manufacture and methods of use of natural topical and oral compositions to treat various dermatitis and pruritus conditions in mammals. In particular, this disclosure relates to a multifunctional topical pharmaceutical composition effective to treat dermatitis and associated pruritus comprising at least one natural plant extract TRPV1 antagonist, at least one natural plant extract is a TRPA1 antagonist, and a carrier.

Abstract: This disclosure relates to natural topical and analgesic pain relief and anti-inflammation compositions and methods to reduce pain and inflammation. This disclosure also relates to the use of cannabinoid compounds in hydrophilic compositions comprised of synthetic and natural plant extract compounds that are multifunctional TRPM8 ion channel agonists, TRPA1 and TRPV1 ion channel antagonists, CGRP antagonists, COX-2 inhibitors and CB1 and CB2 antagonists. In particular, this disclosure relates to a topical analgesic composition comprising at least one synthetic or natural plant extract TRPM8 agonist, at least one synthetic or natural plant extract is a TRPA1 antagonist, and fixed plant seed oil containing Omega-3 fatty acids TRPV1 antagonists and a carrier.

Abstract: This disclosure relates to natural topical and analgesic pain relief and anti-inflammation compositions and methods to reduce pain and inflammation. This disclosure also relates to the use of non-steroidal anti-inflammatory compounds (NSAIDs) in hydrophilic compositions comprised of synthetic and natural plant extract compounds that are multifunctional TRPM8 ion channel agonists, TRPA1 and TRPV1 ion channel antagonists, CGRP antagonists, and COX-2 inhibitors. In particular, this disclosure relates to a topical analgesic composition comprising at least one NSAID, at least one synthetic or natural plant extract TRPM8 agonist, at least one synthetic or natural plant extract is a TRPA1 antagonist, and at least one fixed plant seed oil containing Omega-3 fatty acids TRPV1 antagonists, and a carrier.

Abstract: This disclosure relates to natural topical and analgesic pain relief and anti-inflammation compositions and methods to reduce pain and inflammation. This disclosure also relates to the use of cannabinoid compounds in hydrophilic compositions comprised of synthetic and natural plant extract compounds that are multifunctional TRPM8 ion channel agonists, TRPA1 and TRPV1 ion channel antagonists, CGRP antagonists, COX-2 inhibitors and CB1 and CB2 antagonists. In particular, this disclosure relates to a topical analgesic composition comprising at least one synthetic or natural plant extract TRPM8 agonist, at least one synthetic or natural plant extract is a TRPA1 antagonist, and fixed plant seed oil containing Omega-3 fatty acids TRPV1 antagonists and a carrier.

Abstract: This disclosure relates to devices, methods and compositions for the controlled gas phase time-release of volatile and semi-volatile hydrophobic organic compounds from a granular polymer sorbent-non aqueous phase liquid-porous media matrix. Also, this disclosure relates to devices, methods and compositions for steady and long-term release into the gas phase of volatile organic compounds from a granular polymer sorbent-essential oil matrix coating made at ambient temperatures and pressures and placed in the porosity of granular porous media materials such as plastic particles, plastic absorption or stripping tower mass transfer packing material, wood pellets and geologic material. The gas phase compounds released from the granular polymer sorbent-essential oil matrix have aromatherapy, fragrance, insecticidal and insect repelling properties.

Abstract: Volatile organic compounds are removed from contaminated soil by introducing one or both of a water soluble peroxygen compound, such as a persulfate, and a permanganate into the soil, either in situ or ex situ, in amounts and under conditions wherein both the soil oxidant demand is satisfied and volatile organic compounds in the soil are oxidized. In a preferred embodiment, when both are used, the peroxygen satisfies the soil oxidant demand and the permanganate oxidizes the volatile organic compounds. Sodium persulfate is the preferred persulfate and potassium permanganate is preferred permanganate. The persulfate and the permanganate may be added to the soil sequentially, or may be mixed together and added as an aqueous solution.

Abstract: Volatile organic compounds are removed from contaminated soil by introducing one or both a water soluble peroxygen compound, such as a persulfate, and a permanganate into the soil, either in situ or ex situ, in amounts and under conditions wherein both the soil oxidant demand is satisfied and volatile organic compounds in the soil are oxidized. In a preferred embodiment, when both are used the peroxygen satisfies the soil oxidant demand and the permanganate oxidizes the volatile organic compounds. Sodium persulfate is the preferred persulfate and potassium permanganate is the preferred permanganate. The persulfate and the permanganate may be added to the soil sequentially, or may be mixed together and added as an aqueous solution.