Patents by Inventor George F. El Khoury

George F. El Khoury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topical application of opioid analgesic drugs such as morphine
    Patent number: 6787149
    Abstract: The invention is directed to methods and pharmaceutical compositions for the topical administration of opioid analgesic drugs such as morphine. In particular, the invention relates to topical administration of an opioid analgesic agent, e.g., morphine sulfate, to produce a localized analgesic effect in inflamed skin or mucosal tissue, and without a transdermal or transmucosal migration of opioid agent, e.g., into the systemic circulation.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: September 7, 2004
    Assignee: El Khoury and Stein Ltd.
    Inventors: George F. El Khoury, Christoph Stein
  • Topical application of muscarinic and opioid agents for treatment of tinnitus
    Patent number: 6465442
    Abstract: The present invention relates to a compositions and methods for treating tinnitus. In preferred embodiments of the invention, muscurinic and/or opioid agents are administered to the affected ear in amount effective to relieve one or more tinnitus symptoms. A preferred agent is an anticholinesterase inhibitor, such as neoostigmine.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: October 15, 2002
    Inventor: George F. El Khoury
  • Topical application of muscarinic and opioid agents for treatment of tinnitus
    Publication number: 20020010191
    Abstract: The present invention relates to a compositions and methods for treating tinnitus. In preferred embodiments of the invention, muscurinic and/or opioid agents are administered to the affected ear in amount effective to relieve one or more tinnitus symptoms. A preferred agent is an anticholinesterase inhibitor, such as neoostigmine.
    Type: Application
    Filed: July 17, 2001
    Publication date: January 24, 2002
    Inventor: George F. El Khoury
  • Topical application of muscarinic and opioid agents for treatment of tinnitus
    Patent number: 6262063
    Abstract: The present invention relates to a compositions and methods for treating tinnitus. In preferred embodiments of the invention, muscurinic and/or opioid agents are administered to the affected ear in amount effective to relieve one or more tinnitus symptoms. A preferred agent is an anticholinesterase inhibitor, such as neoostigmine.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: July 17, 2001
    Inventor: George F. El Khoury
  • Topical application of muscarinic analgesic drugs such as neostigmine
    Patent number: 6011022
    Abstract: The invention is directed to methods and pharmaceutical compositions for the topical administration of analgesic drugs which affects peripheral muscarinic receptors such as neostigmine. In particular, the invention relates to topical administration of an analgesic agent, e.g., neostigmine, optionally in admixture with a skin- or mucosal-specific penetration enhancer, to produce a localized analgesic effect in inflamed or non-inflamed skin or mucosal tissue, and without a transdermal or transmucosal migration of the agent, e.g., into the central nervous system.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: January 4, 2000
    Inventor: George F. El Khoury
  • Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions
    Patent number: 5994330
    Abstract: Treatment of acne through topical administration is an aspect of the present invention. Specifically, muscarinic agents may be applied in any therapeutically acceptable carrier including gels, creams, lotions, and sprays. Therapeutic effects observed with the present invention include decrease in redness, swelling, and inflammation. Treatment of other inflammatory conditions is also disclosed. Treatment of suitable conditions in accordance with the present invention results in significant improvements in healing of those conditions.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: November 30, 1999
    Inventor: Georges F. El Khoury