Patents by Inventor George F. Gao

George F. Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Complex of hepatitis B virus-specific antigenic peptides associated with heat shock proteins and the application thereof
    Patent number: 7247712
    Abstract: The present invention provides a kind of HBV-antigen bound to heat shock proteins (hsps) which comprises core antigen, surface antigen and polymerase antigen. The present invention also provides a complex of HBV antigen bound to heat shock protein gp96 and hsp78, as well as a method for preparing the complex. The complex includes a complex of gp96 and hsp78 non-covalently bound to antigenic polypeptide, as well as a fusion protein of both which results from covalent binding. Such complex can be used to prepare therapeutic vaccine for treating hepatitis B and primary hepatocellular carcinoma.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: July 24, 2007
    Assignee: Institute of Microbiology, Chinese Academy of Sciences
    Inventors: Bo Tian, Songdong Meng, George F. Gao
  • Hepatitis b virus (hbv) antigenic polypeptide-heat shock protein complex and use thereof
    Publication number: 20040047879
    Abstract: The present invention provides a kind of HBV-antigen bound to heat shock proteins (hsps) which comprises core antigen, surface antigen and polymerase antigen. The present invention also provides a complex of HBV antigen bound to heat shock protein gp96 and hsp78, as well as a method for preparing the complex. The complex includes a complex of gp96 and hsp78 non-covalently bound to antigenic polypeptide, as well as a fusion protein of both which results from covalent binding. Such complex can be used to prepare therapeutic vaccine for treating hepatitis B and primary hepatocellular carcinoma.
    Type: Application
    Filed: July 28, 2003
    Publication date: March 11, 2004
    Inventors: Bo Tian, Songdong Meng, George F Gao