Patents by Inventor George Fry

George Fry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11795503
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: October 24, 2023
    Assignee: Life Technologies Corporation
    Inventors: George A. Fry, Christina E. Inman, John Bridgham, Timothy Hunkapiller, Charles S. Vann
  • Publication number: 20190338351
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Application
    Filed: July 15, 2019
    Publication date: November 7, 2019
    Inventors: George A. FRY, Christina E. INMAN, John BRIDGHAM, Timothy HUNKAPILLER, Charles S. VANN
  • Patent number: 10351907
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: July 16, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: George A. Fry, Christina E. Inman, John Bridgham, Timothy Hunkapiller, Charles S. Vann
  • Publication number: 20150065356
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Application
    Filed: October 16, 2014
    Publication date: March 5, 2015
    Inventors: George A. FRY, Christina E. INMAN, John BRIDGHAM, Timothy HUNKAPILLER, Charles S. VANN
  • Patent number: 8889596
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: November 18, 2014
    Assignee: Life Technologies Corporation
    Inventors: George A. Fry, Christina E. Inman, John Bridgham, Timothy Hunkapiller, Charles S. Vann
  • Publication number: 20130331276
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Application
    Filed: August 16, 2013
    Publication date: December 12, 2013
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Mark F. OLDHAM, George A. FRY, Christina E. INMAN, John BRIDGHAM, Timothy HUNKAPILLER, Charles S. VANN
  • Patent number: 8536099
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: September 17, 2013
    Assignee: Life Technologies Corporation
    Inventors: Mark Oldham, George Fry, Christina Inman, John Bridgham, Timothy Hunkapillar, Charles Vann
  • Patent number: 8173198
    Abstract: Intermediates and methods for forming activated metal complexes bound to surfaces on oxide layers, immobilizing beads to the modified surface and articles produced thereby are described. Hydroxyl groups on the oxide surfaces are reacted with a metal reagent complex of the formula Y(L-Pol)m, where Y is a transition metal, magnesium or aluminum, L is oxygen, sulfur, selenium or an amine, and “Pol” represents a passivating agent such as a methoxyethanol, a polyethylene glycol, a hydrocarbon, or a fluorocarbon. The resulting modified surface can be further reacted with a passivating agent having a phosphate functional group or a plurality of functional groups that are reactive with or that form complexes with Y.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: May 8, 2012
    Assignee: Life Technologies Corporation
    Inventors: Steven M. Menchen, Christina E. Inman, Meng Taing, George A. Fry
  • Publication number: 20110136677
    Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.
    Type: Application
    Filed: August 31, 2010
    Publication date: June 9, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Mark OLDHAM, George Fry, Christina Inman, John Bridgham, Timothy Hunkapillar, Charles Vann
  • Patent number: 7797762
    Abstract: A cuff clip secures a loose trouser leg to a shoe, and support the lower edge of such trouser leg above the ground. A fastener is embedded within a lower portion of the shoe, leaving a coupling head exposed outside the shoe. The cuff clip engages the bottom edge of the trouser leg. The cuff clip includes a snap coupler that mates with the coupling head of the fastener embedded within the shoe. An outwardly-directed exterior wall of the cuff clip includes a bottom lip and opposing side lips to releasably receive a rectangular logo.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: September 21, 2010
    Inventors: Howard Shapiro, Ralph Farias, George Fry
  • Patent number: 7747253
    Abstract: Apparatus, and an associated method, for facilitating routing of a data service call background and foreground service delivery modes are defined. A delivery mode type determiner determines the service delivery mode associated with the data service. If the service delivery mode is a background delivery mode, the data service is effectuated with the intended receiving station instead of being redirected pursuant to a call forwarding, or other service interaction indicia, feature.
    Type: Grant
    Filed: January 29, 2004
    Date of Patent: June 29, 2010
    Assignee: Nokia Corporation
    Inventor: George Fry
  • Publication number: 20100086927
    Abstract: Intermediates and methods for forming activated metal complexes bound to surfaces on oxide layers, immobilizing beads to the modified surface and articles produced thereby are described. Hydroxyl groups on the oxide surfaces are reacted with a metal reagent complex of the formula Y(L-Pol)m, where Y is a transition metal, magnesium or aluminum, L is oxygen, sulfur, selenium or an amine, and “Pol” represents a passivating agent such as a methoxyethanol, a polyethylene glycol, a hydrocarbon, or a fluorocarbon. The resulting modified surface can be further reacted with a passivating agent having a phosphate functional group or a plurality of functional groups that are reactive with or that form complexes with Y.
    Type: Application
    Filed: July 23, 2009
    Publication date: April 8, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Steven M. Menchen, Christina E. Inman, Meng Taing, George A. Fry
  • Publication number: 20070277290
    Abstract: A cuff clip secures a loose trouser leg to a shoe, and supports the lower edge of such trouser leg above the ground. A fastener is secured to a lower portion of the shoe, leaving a coupling head or stud exposed outside the shoe. The cuff clip includes a channel to engage the bottom edge of the trouser leg. The cuff clip includes a snap coupler that mates with the coupling head or stud of the fastener embedded within the shoe. An exterior wall of the cuff clip is used to display a logo or other indicia. Such exterior wall has retaining lips to releasably receive indicia to be displayed thereon.
    Type: Application
    Filed: June 5, 2006
    Publication date: December 6, 2007
    Inventors: Howard Shapiro, Ralph Farias, George Fry
  • Publication number: 20060087113
    Abstract: Pre-converted roll stock has a continuous web with printable surfaces that include a plurality of spaced registration marks for reference in positioning converting operations and image printing. The web has been pre-converted by application of remoistenable and pressure sensitive co-adhesive compositions, scratch off coatings, perforations, scores, notches, embossing and die cuts in preselected locations to form templates on the continuous web roll for a variety of printing and packaging applications, including printed pieces with self-mailers, return envelopes, reply cards, presentation folders, boxes and CD jackets. Selected registration marks are used to align an imaging device such as a digital press for printing the pre-converted stock with personalized variable data in the form of text and images.
    Type: Application
    Filed: October 26, 2005
    Publication date: April 27, 2006
    Inventors: Aric Snyder, George Fry
  • Patent number: 6956839
    Abstract: Apparatus, and an associated method, for a radio, such as cellular, communication system to facilitate communications between a mobile station and the network infrastructure. When the mobile station registers in the communication system, a dedicated reverse-link channel is allocated to facilitate communications of packet data between the mobile station and the network infrastructure. By providing dedicated channels, the mobile station becomes functionally connected to the network infrastructure and are analogous to a hard wired connection of a computer in a local area network.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: October 18, 2005
    Assignee: Nokia Corporation
    Inventors: Thomas A. Sexton, George Fry
  • Publication number: 20050130648
    Abstract: Apparatus, and an associated method, for facilitating routing of a data service call background and foreground service delivery modes are defined. A delivery mode type determiner determines the service delivery mode associated with the data service. If the service delivery mode is a background delivery mode, the data service is effectuated with the intended receiving station instead of being redirected pursuant to a call forwarding, or other service interaction indicia, feature.
    Type: Application
    Filed: January 29, 2004
    Publication date: June 16, 2005
    Inventor: George Fry
  • Publication number: 20040117459
    Abstract: The invention provides a method and system for a network having multimedia messaging service (MMS) capability allowing downloading of one or more multimedia messages (MMs) from a server to a client. The client and/or the server is capable of generating commands for suspending and resuming downloading of the multimedia message. When the client or server generates a command for suspending a current downloading of a multimedia message, the server suspends the downloading of the multimedia message, and a marker is generated for marking the position of suspending the multimedia message. When the client or server generates a command for resuming the suspended downloading of the multimedia message, the server resumes the downloading from the position of suspending marked by the marker.
    Type: Application
    Filed: December 12, 2002
    Publication date: June 17, 2004
    Inventor: George Fry
  • Patent number: 6697624
    Abstract: Apparatus, and an associated method, for facilitating routing of a data service call background and foreground service delivery modes are defined. A delivery mode type determiner determines the service delivery mode associated with the data service. If the service delivery mode is a background delivery mode, the data service is effectuated with the intended receiving station instead of being redirected pursuant to a call forwarding, or other service interaction indicia, feature.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: February 24, 2004
    Assignee: Nokia Mobile Phones Ltd.
    Inventor: George Fry
  • Patent number: 6638760
    Abstract: The present invention provides substrates and apparatuses for efficient, rapid and specific capture, and optimal recovery, of nucleic acids, as well as methods of their use. The substrate is porous in nature and has a capture polynucleotide capable of hybridizing to a target nucleic acid immobilized thereon. Upon flowing a sample containing or suspected of containing the target nucleic acid through the porous substrate, the target nucleic acid is rapidly captured. Following capture, the target nucleic acid can be efficiently recovered for subsequent use.
    Type: Grant
    Filed: December 3, 1998
    Date of Patent: October 28, 2003
    Assignee: PE Corporation (NY)
    Inventors: Jer-Kang Chen, Claudia Chiesa, George A. Fry, Vergine C. Furniss, Stephen M. Lambert, Roger O'Neill, Majid Mehrpouyan
  • Patent number: 6614772
    Abstract: Apparatus, and an associated method, for a radio, such as cellular, communication system to facilitate communications between a mobile station and the network infrastructure. When the mobile station registers in the communication system, a dedicated reverse-link channel is allocated to facilitate communications of packet data between the mobile station and the network infrastructure. By providing dedicated channels, the mobile station becomes functionally connected to the network infrastructure and are analogous to a hard wired connection of a computer in a local area network.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: September 2, 2003
    Assignee: Nokia Corporation
    Inventors: Thomas A. Sexton, George Fry