Patents by Inventor George G. Klee

George G. Klee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10407731
    Abstract: This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the time of PSA reoccurrence, will later develop systemic disease, (2) which patients, at the time of retropubic radial prostatectomy, will later develop systemic disease, and (3) which patients, at the time of systemic disease, will later die from prostate cancer are provided.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: September 10, 2019
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: George G. Klee, Robert B. Jenkins, Thomas M. Kollmeyer, Karla V. Ballman, Eric J. Bergstralh, Bruce W. Morlan, S. Keith Anderson, Tohru Nakagawa
  • Publication number: 20180312926
    Abstract: This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the time of PSA reoccurrence, will later develop systemic disease, (2) which patients, at the time of retropubic radial prostatectomy, will later develop systemic disease, and (3) which patients, at the time of systemic disease, will later die from prostate cancer are provided.
    Type: Application
    Filed: September 17, 2015
    Publication date: November 1, 2018
    Inventors: George G. Klee, Robert B. Jenkins, Thomas M. Kollmeyer, Karla V. Ballman, Eric J. Bergstralh, Bruce W. Morlan, S. Keith Anderson, Tohru Nakagawa
  • Publication number: 20160010162
    Abstract: This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the time of PSA reoccurrence, will later develop systemic disease, (2) which patients, at the time of retropubic radial prostatectomy, will later develop systemic disease, and (3) which patients, at the time of systemic disease, will later die from prostate cancer are provided.
    Type: Application
    Filed: September 17, 2015
    Publication date: January 14, 2016
    Inventors: George G. Klee, Robert B. Jenkins, Thomas K. Kollmeyer, Karla V. Ballman, Eric J. Bergstralh, Bruce W. Morlan, S. Keith Anderson, Tohru Nakagawa
  • Publication number: 20150024420
    Abstract: This document relates to methods and materials involved in identifying, assessing, and monitoring prostate cancer in male mammals. For example, this document provides arrays for detecting polypeptides or nucleic acids that can be used to identify prostate cancer in male mammals. In addition, methods and materials for assessing and monitoring prostate cancer in mammals are provided herein.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
  • Patent number: 8871451
    Abstract: This document relates to methods and materials involved in identifying, assessing, and monitoring prostate cancer in male mammals. For example, this document provides arrays for detecting polypeptides or nucleic acids that can be used to identify prostate cancer in male mammals. In addition, methods and materials for assessing and monitoring prostate cancer in mammals are provided herein.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: October 28, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
  • Publication number: 20130004974
    Abstract: This document relates to methods and materials involved in identifying, assessing, and monitoring prostate cancer in male mammals. For example, this document provides arrays for detecting polypeptides or nucleic acids that can be used to identify prostate cancer in male mammals. In addition, methods and materials for assessing and monitoring prostate cancer in mammals are provided herein.
    Type: Application
    Filed: September 7, 2012
    Publication date: January 3, 2013
    Inventors: George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
  • Patent number: 8273539
    Abstract: This document relates to methods and materials involved in identifying, assessing, and monitoring prostate cancer in male mammals. For example, this document provides arrays for detecting polypeptides or nucleic acids that can be used to identify prostate cancer in male mammals. In addition, methods and materials for assessing and monitoring prostate cancer in mammals are provided herein.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: September 25, 2012
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
  • Publication number: 20100028881
    Abstract: This document relates to methods and materials involved in identifying, assessing, and monitoring prostate cancer in male mammals. For example, this document provides arrays for detecting polypeptides or nucleic acids that can be used to identify prostate cancer in male mammals. In addition, methods and materials for assessing and monitoring prostate cancer in mammals are provided herein.
    Type: Application
    Filed: September 25, 2007
    Publication date: February 4, 2010
    Inventors: George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
  • Publication number: 20090298082
    Abstract: This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the time of PSA reoccurrence, will later develop systemic disease, (2) which patients, at the time of retropubic radial prostatectomy, will later develop systemic disease, and (3) which patients, at the time of systemic disease, will later die from prostate cancer are provided.
    Type: Application
    Filed: May 29, 2009
    Publication date: December 3, 2009
    Inventors: George G. Klee, Robert B. Jenkins, Thomas M. Kollmeyer, Karla V. Ballman, Eric J. Bergstralh, Bruce W. Morlan, S. Keith Anderson, Tohru Nakagawa
  • Patent number: 6787361
    Abstract: A method for calibrating a clinical laboratory analytical instrument that includes generating control pool data from a commutable control pool, wherein the control pools have target analyte values for an assay, generating patient specimen data from a distribution of test values from patient specimens, determining tolerance limits from the control pool data and the patient specimen data; and adjusting the calibration of the instrument with respect to the tolerance limits.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: September 7, 2004
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: George G. Klee
  • Patent number: 6235486
    Abstract: Breast cancer is detected by determining the presence of hK2 polypeptide or hK2 RNA in a physiological sample.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: May 22, 2001
    Assignee: Mayo Foundation for Medical Education & Research
    Inventors: Charles Y. F. Young, Donald J. Tindall, George G. Klee
  • Patent number: 5891651
    Abstract: A method of recovering colorectal epithelial cells or fragments thereof from a stool sample is provided. The method involves contacting a stool sample with a specific binding reagent having specificity for colorectal epithelial cells or membrane fragments thereof to form a complex containing the specific binding reagent and the colorectal epithelial cells or fragments thereof, and separating the complex from the sample. A method of detecting dysplastic colorectal epithelial cells or fragments thereof, wherein a specific binding reagent employed in the method has specificity for dysplastic colorectal epithelial cells or membrane fragments thereof, is also provided. An article of manufacture containing reagents for performing the method is further provided.
    Type: Grant
    Filed: March 29, 1996
    Date of Patent: April 6, 1999
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Patrick C. Roche, George G. Klee, Paul J. Limburg, David A. Ahlquist
  • Patent number: 5516639
    Abstract: The present invention provides an isolated preparation of monoclonal or polyclonal antibodies which react specifically with human prostate-specific glandular kallikrein (hK2), but which do not cross-react with human prostate-specific antigen (PSA), as well as immunogenic hK2 antigens useful to provide such antibodies.
    Type: Grant
    Filed: July 22, 1993
    Date of Patent: May 14, 1996
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Donald J. Tindall, Charles Y. F. Young, George G. Klee