Patents by Inventor George G. Zhanel

George G. Zhanel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial compositions comprising a hyaluronic acid binding peptide and a ?-lactam antibiotic
    Patent number: 9751919
    Abstract: Compositions and methods for the treatment of antibiotic resistant Staphylococcus aureus infections are provided comprising ?-lactam antibiotics, as well as a hyaluronic acid binding peptide. The antibiotics include cephalosporins as well as the ?o?-? lactam antibiotic vancomycin. The methods provide administering the composition to the subject in an amount effective to reduce or eliminate the infection.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: September 5, 2017
    Assignee: EMERGENT BIOSOLUTIONS CANADA INC.
    Inventors: Laura Saward, Xiaobing Han, George G. Zhanel
  • ANTIMICROBIAL COMPOSITIONS COMPRISING A HYALURONIC ACID BINDING PEPTIDE AND A beta-LACTAM ANTIBIOTIC
    Publication number: 20150218235
    Abstract: Compositions and methods for the treatment of antibiotic resistant Staphylococcus aureus infections are provided comprising ?-lactam antibiotics, as well as a hyaluronic acid binding peptide. The antibiotics include cephalosporins as well as the ?o?-? lactam antibiotic vancomycin. The methods provide administering the composition to the subject in an amount effective to reduce or eliminate the infection.
    Type: Application
    Filed: May 3, 2013
    Publication date: August 6, 2015
    Inventors: Laura Saward, Xiaobing Han, George G. Zhanel
  • Hydrophobically enhanced aminoglycosides
    Patent number: 8865664
    Abstract: Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections. Methods of preparing these agents also permit facile synthetic access. Formula (I).
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: October 21, 2014
    Assignee: University of Manitoba
    Inventors: Smritilekha Bera, George G. Zhanel, Frank Schweizer
  • HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES
    Publication number: 20110178037
    Abstract: Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections. Methods of preparing these agents also permit facile synthetic access. Formula (I).
    Type: Application
    Filed: July 9, 2009
    Publication date: July 21, 2011
    Applicant: UNIVERSITY OF MANITOBA
    Inventors: Smritilekha Bera, George G. Zhanel, Frank Schweizer
  • TRIAZOLE-BASED AMINOGLYCOSIDE-PEPTIDE CONJUGATES AND METHODS OF USE
    Publication number: 20100261639
    Abstract: Aminoglycoside-amino acid and -peptide conjugates comprising a triazolyl linker are provided along with efficient methods of their preparation. The aminoglycoside may be an aminoglycoside antibiotic. Conjugates comprising an aminoglycoside antibiotic may exhibit antimicrobial activities against Gram-positive and/or Gram-negative strains and display significantly enhanced activity against multi-drug resistant MRSA and MRSE when compared to their unconjugated aminoglycoside antibiotic counterparts.
    Type: Application
    Filed: May 28, 2008
    Publication date: October 14, 2010
    Applicant: UNIVERSITY OF MANITOBA
    Inventors: Frank Schweizer, George G. Zhanel, Smritilekha Bera