Patents by Inventor George Grass

George Grass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ABSORBENT POLYMERIC COMPOSITIONS WITH VARYING COUNTERION CONTENT AND THEIR METHODS OF PREPARATION AND USE
    Publication number: 20110123604
    Abstract: Cross-linked polyelectrolyte polymers with bound counterions that absorb about 20-fold or more of their mass in saline such as physiological saline a with the proviso that sodium does not exceed 60% of total bound counterions when hydrogen is the sole other counterion, are disclosed. Methods of preparing the disclosed polymers and for treating subjects such as patients in need of fluid removal and/or modulation of ions (e.g., sodium and/or potassium) are provided.
    Type: Application
    Filed: August 29, 2008
    Publication date: May 26, 2011
    Applicant: SORBENT THERAPEUTICS, INC.
    Inventors: Alan Strickland, George Grass
  • POLYMERIC COMPOSITIONS WITH ENHANCED SALINE HOLDING CAPACITY AND THEIR METHOD OF PREPARATION AND USE
    Publication number: 20110104212
    Abstract: Cross-linked polyelectrolyte polymers that absorb 60-fold or more, including greater than 60-fold, greater than 70-fold, greater than 80-fold, greater than 90-fold, greater than 100-fold, or greater than 110-fold or more, of their mass in a saline solution are disclosed. Methods for preparing such polymers with enhanced saline holding capacity and methods for treating diseases, disorders or conditions involving fluid overload and/or ion imbalances by administering the polymers are disclosed.
    Type: Application
    Filed: August 29, 2008
    Publication date: May 5, 2011
    Applicant: SORBENT THERAPEUTICS, INC.
    Inventors: Alan Strickland, George Grass
  • POLYMERIC COMPOSITIONS AND THEIR METHOD OF USE IN COMBINATION WITH ACTIVE AGENTS
    Publication number: 20110091540
    Abstract: A combination of active agents is disclosed which are particularly useful for treating fluid overload conditions. Methods for using the combination of active agent are also disclosed. The combination can include a highly absorbent polyelectrolyte polymer along with an agent that increases the amount of fluid in the intestine.
    Type: Application
    Filed: August 29, 2008
    Publication date: April 21, 2011
    Inventors: Alan Strickland, George Grass
  • System and method for predicting adme/tox characteristics of a compound
    Publication number: 20040009536
    Abstract: A method for developing a predictive model of a chemical compound property. The method includes obtaining at least one descriptor from structural data for each of a plurality of compounds. At least one chemical compound property is obtained for each of the plurality of compounds. The predictive model is developed by mapping the at least one descriptor to the chemical compound property. The chemical compound property may be an ADME property. The ADME property may be absorption. The chemical compound property may also be an toxicity property.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 15, 2004
    Inventors: George Grass, Glen D Leesman, Daniel Norris, Patrick Sinko, Jehangir Athwal, Carleton Sage, Troy Bremer, Kevin Holme