Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: An automated fruit harvester which includes sensors and robotic arms which position themselves adjacent to a fruit to be harvested. A fruit transport head secures the fruit, cuts the stem, and transports the fruit within the hollow arm, to deposit the fruit in a collection bin.

Abstract: The present invention is an apparatus to be connected to the end of a fire hose that will allow a nozzle operator to perform mop-up fire fighting work without a shovel man and to extinguish both below-ground pockets of smoldering material and small surface fires. The apparatus incorporates a low-pressure, air-aspirated nozzle mounted on an elongated conduit that can be used for both the above-ground and below-ground work, can be used with fire foam, can extend the useful reach of fire hose equipment and can lengthen the use time for a given volume of water contained in a portable tank. Mop-up work refers to the process of extinguishing smoldering pockets of compacted organic material on and below the ground and small flare-ups that remain after the primary surface fire of a forest or grassland fire has swept through an area or been extinguished.

Abstract: The invention is an automated fruit harvester which includes sensors and robotic arms which position themselves adjacent to a fruit to be harvested. A fruit transport head secures the fruit, cuts the stem, and transports the fruit within the hollow arm, to deposit the fruit in a collection bin.

Abstract: The present invention relates to the field of therapeutic chemistry and more especially to the realization of new galenic forms intended to be applied on the skin. More particularly it relates to a topical hormonal composition with a systemic effect for the hormonal treatment of the perimenopause and of the menopause as well as for the treatment of the ovarian hormonal deficiencies in women with amenorrhea, characterized in that it comprises, as active ingredients, a progestogen derived from 19-nor progesterone and estradiol or one of its derivatives, a vehicle which allows the systemic passage of said active ingredients, chosen from the group constituted by a solubilizing agent, an absorption promoting agent, a film-forming agent, a gelling agent and their mixtures, in combination or in a mixture with suitable excipients for the realization of a gelled and/or film-forming pharmaceutical form.

Abstract: The present invention is an apparatus to be connected to the end of a fire hose that will allow a nozzle operator to perform mop-up fire fighting work without a shovel man and to extinguish both below-ground pockets of smoldering material and small surface fires. The apparatus incorporates a low-pressure, air-aspirated nozzle mounted on an elongated conduit that can be used for both the above-ground and below-ground work, can be used with fire foam, can extend the useful reach of fire hose equipment and can lengthen the use time for a given volume of water contained in a portable tank. Mop-up work refers to the process of extinguishing smoldering pockets of compacted organic material on and below the ground and small flare-ups that remain after the primary surface fire of a forest or grassland fire has swept through an area or been extinguished.

Abstract: The present invention relates to the field of therapeutic chemistry and more especially to the realization of new galenic forms intended to be applied on the skin.

Abstract: A lever and latch assembly for a split ring for securing a cover on a drum includes a bar on the lever for disposition in a pocket of latch with a snap action. An enlarged finger engaging flange on the latch facilitates movement to a latched position and an unlatched position with a suitable tool. The assembly is designed to accommodate domestic and international seals for security purposes.

Abstract: A fluorescent lamp is operated by a-c pulses having a pulse length sufficiently short that the lamp acts like slightly positive impedances. A pulse modulator which produces the pulses has a power transistor biased to saturation. However, varying the base drive of the saturated transistor causes a generally linear change in tube current to permit tube dimming and control. A servo circuit provides feedback control of the base drive to automatically compensate for variable effects to maintain constant tube lighting. Tube dimming is obtained by adjusting the feedback circuits of the servo.