Abstract: Disclosed herein is an implantable accommodative IOL device for insertion into an eye of a patient, comprising an active region and a passive region. The active region has a first thickness and first refractive index, and the active region comprises an electrically responsive optical lens having variable optical power. The passive region is disposed at a periphery of the active region, and the passive region has a second thickness and a second refractive index. The second refractive index is different than the first refractive index. Thus, the light beams passing through the active and passive regions have a phase difference, thereby providing an extended depth of field.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a conical flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: A system for determining an accommodative force in a patient includes a sensor adapted to detect motion of a lens of the patient relative to a globe of the patient's eye, a controller configured to determine an accommodative force in the patient based on the relative motion and to determine at least one parameter for an intraocular lens based on the accommodative force, and an interface adapted to output the at least one parameter for the intraocular lens.

Abstract: An electro-active ophthalmic lens includes an electromyography sensor, a processor, and an electro-active optical element. The electromyography sensor is configured to detect an electric field in a ciliary muscle of the eye that is proportional to a force exerted by the ciliary muscle and to generate a sensor signal indicative of the electric field. The processor is operable to receive the signal from the electromyography sensor and to determine, based on the sensor signal, an adjustment to optical power for an electro-active optical element and to generate a control signal for the electro-active optical element. The electro-active optical element is operable to receive the control signal and to change an optical power of the electro-active optical element in response to the control signal.

Abstract: A system for determining an accommodative force in a patient includes a sensor adapted to detect motion of a lens of the patient relative to a globe of the patient's eye, a controller configured to determine an accommodative force in the patient based on the relative motion and to determine at least one parameter for an intraocular lens based on the accommodative force, and an interface adapted to output the at least one parameter for the intraocular lens.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a conical flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a corneal flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: An electro-active ophthalmic lens includes an electromyography sensor, a processor, and an electro-active optical element. The electromyography sensor is configured to detect an electric field in a ciliary muscle of the eye that is proportional to a force exerted by the ciliary muscle and to generate a sensor signal indicative of the electric field. The processor is operable to receive the signal from the electromyography sensor and to determine, based on the sensor signal, an adjustment to optical power for an electro-active optical element and to generate a control signal for the electro-active optical element. The electro-active optical element is operable to receive the control signal and to change an optical power of the electro-active optical element in response to the control signal.

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription.

Abstract: The present invention is related to an adjustable intraocular lens system comprised of a lens body having an adjustable refractive index and a shield for protecting the lens body from degradation that might otherwise be caused by exposure to particular electromagnetic radiation. More preferably, the present invention is directed to an adjustable intraocular lens system comprised of a lens body and a shield wherein the lens body is formed of a material with a refractive index that can be adjusted by exposure to adjusting electromagnetic radiation (e.g., multiple photon energy) and wherein the shield protects the lens body from degradation that might otherwise be caused by exposure to degrading electromagnetic radiation such as ultraviolet radiation.

Abstract: A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription.

Abstract: A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.

Abstract: A gas-purged laser system and method of gas-purging a laser system are disclosed. One embodiment of the laser system comprises an excimer refractive surgical laser system having a laser beam optical path configured to allow purging of a portion of a volume enclosing the laser beam optical path with a gas, and a gas generator, operable to generate the purging gas and provide the gas to the volume portion. The portion of the volume can be the entire volume enclosing the laser beam optical path or a selected portion thereof. The gas can be nitrogen gas and the gas generator can be a self-contained nitrogen generator as will be known to those having skill in the art. Embodiments can further comprise a controller for controlling the flow of purging gas in response to received signals representative of various parameters, such as temperature, oxygen level, pressure, humidity and flow rate.

Abstract: A method for assessing a performance of an ablation laser system includes ablating a substrate surface to achieve a predetermined ablation pattern. A beam of light is directed across the ablated substrate, and reflected light is received to detect an actual ablated pattern, which is compared with the predetermined ablated pattern. The resulting comparison is displayed to a user so that the performance of the laser system can be assessed. A system includes a support that is adapted to hold an ablation substrate at a treatment plane. An optical scanner directs a beam of light across the ablated substrate and receives light reflected therefrom to detect an ablated pattern. An analyzer compares the detected with a predetermined ablated pattern. A display in signal communication with the analyzer displays a comparison of the detected and the predetermined ablated pattern.

Abstract: A system for controlling a device in ophthalmic refractive surgery includes a processor, a controller, a treatment laser, and a signal receiver. A remote device has a plurality of input elements. At least one input element when activated is configured to emit a discrete signal that is received by the signal receiver and is mapped to an action to be signaled by the controller. A software package is adapted to translate data from the signal receiver into a signal for directing at least the controller. A method for configuring a system for controlling a device in ophthalmic refractive surgery includes providing a remote device as above. A software package resident on a processor receives and translates signal data from the remote device into control data for a hardware element. The software package is also adapted to output a control signal correlated with the control data to the hardware element.

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment achieves the modification of wavefront-based refractive correction data with the use of user/doctor-input nomograms. Data comprising a wavefront description of a patient eye are received and displayed to a user, who can then make modifications to these treatment data. A modification is calculated based upon the desired correction to yield corrected wavefront description data, which are displayed to the user. A system includes a processor and a device for transmitting a wavefront description of a patient eye to the processor. An input device is adapted to receive a desired correction to the wavefront description data. Software is resident on the processor having code segments for implementing the calculations as described.

Abstract: A system and method for converting measured wavefront data into an ablation profile for correcting visual defects includes providing measured wavefront data on an aberrated eye by a method such as known in the art. The measured wavefront data are correlated with accumulated data on previously treated eyes. Next an adjustment is applied to the measured wavefront data based upon the correlating step. This adjustment is used to form adjusted wavefront data for input to a wavefront data correction algorithm to calculate an ablation profile therefrom. The wavefront data correction algorithm may be modeled as, for example, Zernike polynomials with adjusted coefficients.

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment includes the steps of receiving a measured correction prescription for a current patient having a classification element associated therewith, the prescription having been measured using wavefront determination. A database of treatment outcomes on a plurality of previously treated patients is accessed, each treated patient outcome having associated therewith at least one classification element and comprising a preoperative wavefront-determined correction prescription and a postoperative visual profile. From the treatment outcomes in the database is calculated an average difference between the preoperative prescription and the postoperative profile for at least some of the previously treated patients having a classification element in common with the current patient. Finally the current patient correction prescription is adjusted commensurate with the calculated average difference to form an optimized prescription.

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment includes the steps of receiving a measured correction prescription for a current patient having a classification element associated therewith, the prescription having been measured using wavefront determination. A database of treatment outcomes on a plurality of previously treated patients is accessed, each treated patient outcome having associated therewith at least one classification element and comprising a preoperative wavefront-determined correction prescription and a postoperative visual profile. From the treatment outcomes in the database is calculated an average difference between the preoperative prescription and the postoperative profile for at least some of the previously treated patients having a classification element in common with the current patient. Finally the current patient correction prescription is adjusted commensurate with the calculated average difference to form an optimized prescription.