Patents by Inventor George Hajishengallis

George Hajishengallis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating or preventing periodontitis and diseases associated with periodontitis
    Patent number: 10668135
    Abstract: The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for compounds that can be used to prevent or treat periodontitis or diseases associated with periodontitis.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: June 2, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, George Hajishengallis
  • METHODS OF TREATING OR PREVENTING PERIODONTITIS AND DISEASES ASSOCIATED WITH PERIODONTITIS
    Publication number: 20170202935
    Abstract: The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for compounds that can be used to prevent or treat periodontitis or diseases associated with periodontitis.
    Type: Application
    Filed: January 27, 2017
    Publication date: July 20, 2017
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, George Hajishengallis
  • COMPOSITIONS AND METHODS OF REGULATING BONE RESORPTION
    Publication number: 20170136089
    Abstract: The present invention includes compositions and methods that take advantage of MFG-E8's role as a homeostatic regulator of osteoclasts for treating a bone disorder or regulating osteoclast activation. In one aspect, the invention includes a composition comprising an effective amount of milk fat globule-EGF factor 8 (MFG-E8) formulated for local administration and a pharmaceutically acceptable carrier or adjuvant. In another aspect, a method is included for regulating osteoclast activation and inhibiting bone loss at a target site comprising locally administering an effective amount of milk fat globule-EGF factor 8 (MFG-E8) to the target site.
    Type: Application
    Filed: May 12, 2015
    Publication date: May 18, 2017
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: George HAJISHENGALLIS, Toshiharu ABE, Jieun SHIN
  • Methods of treating or preventing periodontitis and diseases associated with periodontitis
    Patent number: 9579360
    Abstract: The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for compounds that can be used to prevent or treat periodontitis or diseases associated with periodontitis.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: February 28, 2017
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, George Hajishengallis
  • METHODS OF TREATING PERIODONTAL INFLAMMATION AND PERIODONTAL BONE LOSS
    Publication number: 20140302027
    Abstract: Methods and compositions for use in treating periodontitis include a Del-1 polypeptide.
    Type: Application
    Filed: September 26, 2012
    Publication date: October 9, 2014
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: George Hajishengallis, Triantafyllos Chavakis
  • METHODS OF TREATING OR PREVENTING PERIODONTITIS AND DISEASES ASSOCIATED WITH PERIODONTITIS
    Publication number: 20130344082
    Abstract: The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for compounds that can be used to prevent or treat periodontitis or diseases associated with periodontitis.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 26, 2013
    Inventors: John D. Lambris, George Hajishengallis