Patents by Inventor George HARTOULAROS

George HARTOULAROS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DELIVERY OF BIOMOLECULES TO IMMUNE CELLS
    Publication number: 20220064584
    Abstract: A method and device for preferentially delivering a compound such as an antigen to the cytosol of an immune cell. The method comprises passing a cell suspension comprising the target immune cell through a microfluidic device and contacting the suspension with the compound(s) or payload to be delivered.
    Type: Application
    Filed: August 4, 2021
    Publication date: March 3, 2022
    Applicants: Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Armon R. Sharei, Shirley Mao, George Hartoularos, Sophia Liu, Megan Heimann, Pamela Basto, Gregory Szeto, Siddharth Jhunjhunwala, Darrell J. Irvine, Robert S. Langer, Klavs F. Jensen, Ulrich H. Von Andrian
  • Delivery of biomolecules to immune cells
    Patent number: 11111472
    Abstract: A method and device for preferentially delivering a compound such as an antigen to the cytosol of an immune cell. The method comprises passing a cell suspension comprising the target immune cell through a microfluidic device and contacting the suspension with the compound(s) or payload to be delivered.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: September 7, 2021
    Assignees: Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Armon R. Sharei, Shirley Mao, George Hartoularos, Sophia Liu, Megan Heimann, Pamela Basto, Gregory Szeto, Siddharth Jhunjhunwala, Darrell Irvine, Robert S. Langer, Klavs F. Jensen, Ulrich H. Von Andrian
  • DELIVERY OF BIOMOLECULES TO IMMUNE CELLS
    Publication number: 20180142198
    Abstract: A method and device for preferentially delivering a compound such as an antigen to the cytosol of an immune cell. The method comprises passing a cell suspension comprising the target immune cell through a microfluidic device and contacting the suspension with the compound(s) or payload to be delivered.
    Type: Application
    Filed: October 30, 2015
    Publication date: May 24, 2018
    Inventors: Armon R. SHAREI, Shirley MAO, George HARTOULAROS, Sophia LIU, Megan HEIMANN, Pamela BASTO, Gregory SZETO, Siddarth JHUNJHUNWALA, Darrell IRVINE, Robert S. LANGER, Klavs F. JENSEN, Ulrich H. VON ANDRIAN