Patents by Inventor George Ksander

George Ksander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating ophthalmic disorders using TGF -.beta.
    Patent number: 5767079
    Abstract: This invention is a method for the treatment of ophthalmic disorders. The method is suitable for treatment of a variety of disorders including macular holes, macular degeneration, and retinal detachment and tears, cataracts, and corneal and scleral injuries. The method entails application of an effective amount of Transforming Growth Factor-.beta. (TGF-.beta.) to the affected region.
    Type: Grant
    Filed: August 27, 1996
    Date of Patent: June 16, 1998
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Bert M. Glaser, Bruce B. Pharriss, deceased, Ann F. Hanham, George A. Ksander
  • Collagen wound healing matrices and process for their production
    Patent number: 5219576
    Abstract: Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves as an effective sustained delivery system for bioactive agents.
    Type: Grant
    Filed: December 3, 1991
    Date of Patent: June 15, 1993
    Assignee: Collagen Corporation
    Inventors: George H. Chu, Yasushi Ogawa, John M. McPherson, George Ksander, Bruce Pratt, Diana Hendricks, Hugh McMullin
  • Processes for producing collagen matrixes and methods of using same
    Patent number: 5110604
    Abstract: Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves as an effective sustained delivery system for bioactive agents.
    Type: Grant
    Filed: December 19, 1990
    Date of Patent: May 5, 1992
    Assignee: Collagen Corporation
    Inventors: George H. Chu, Yasushi Ogawa, John M. McPherson, George Ksander, Bruce Pratt, Diana Hendricks, Hugh McMullin
  • Collagen wound healing matrices and process for their production
    Patent number: 5024841
    Abstract: Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves as an effective sustained delivery system for bioactive agents.
    Type: Grant
    Filed: June 30, 1988
    Date of Patent: June 18, 1991
    Assignee: Collagen Corporation
    Inventors: George H. Chu, Yasushi Ogawa, John M. McPherson, George Ksander, Bruce Pratt, Diana Hendricks, Hugh McMullin
  • Collagen wound healing matrices and process for their production
    Patent number: 4950483
    Abstract: Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves an an effective sustained delivery system for synergistic combinations of FGF and TGF-B.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: August 21, 1990
    Assignee: Collagen Corporation
    Inventors: George Ksander, Yasushi Ogawa
  • Collagen coated soft tissue prostheses
    Patent number: 4772285
    Abstract: An improved soft tissue implant which resists capsule formation and contracture is described. The implant is coated with a non-immunogenic collagen preparation optionally stabilized by crosslinking.
    Type: Grant
    Filed: October 30, 1986
    Date of Patent: September 20, 1988
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: George Ksander, Leonard Gray
  • Wound-healing composition
    Patent number: 4760131
    Abstract: A soft tissue wound healing composition comprising an aqueous mixture of fibrillar collagen, heparin, and undegranulated platelets or platelet releasate. The composition is applied topically to the wound site in conjunction with means to keep it at the site and hydrated or in the form of an occlusive dressing.
    Type: Grant
    Filed: June 23, 1986
    Date of Patent: July 26, 1988
    Assignee: Collagen Corporation
    Inventors: John S. Sundsmo, George A. Ksander, John M. McPherson