Patents by Inventor George L. Leung
George L. Leung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11955207Abstract: The disclosure provides systems and methods for data analysis of experimental data. The analysis can include reference data that are not directly generated from the present experiment, which reference data may be values of the experimental parameters that were either provided by a user, computed by the system with input from a user, or computed by the system without using any input from a user. Another example of such reference data may be information about the instrument, such as the calibration method of the instrument.Type: GrantFiled: June 30, 2016Date of Patent: April 9, 2024Assignee: Emerald Cloud Lab, Inc.Inventors: Alex M. Yoshikawa, Anand V. Sastry, Asuka Ota, Ben C. Kline, Bradley M. Bond, Brian M. Frezza, Cameron R. Lamoureux, Catherine L. Hofler, Cheri Y. Li, Courtney E. Webster, Daniel J. Kleinbaum, George N. Stanley, George W. Fraser, Guillaume Robichaud, Hayley E. Buchman, James R. McKernan, Jonathan K. Leung, Paul R. Zurek, Robert M. Teed, Ruben E. Valas, Sean M. Fitzgerald, Sergio I. Villarreal, Shayna L. Hilburg, Shivani S. Baisiwala, Srikant Vaithilingam, Wyatt J. Woodson, Yang Choo, Yidan Y. Cong
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Patent number: 9039698Abstract: An RF ablation system has a hollow conductive coaxial cable comprising inner and outer coaxial tubular conductors, and an ablating member mounted at the distal end portion of the cable for delivery of radio frequency energy including microwaves to the target body tissue. The inner conductor has a central lumen and extends at least up to the ablating member. At least one electromagnetic tracking sensor coil with a magnetic core is located in the central lumen at the distal end portion of the cable, close to the distal tip of the cable, and connected to a signal processing unit. An electromagnetic field generator positioned in the vicinity of a patient undergoing treatment generates an electromagnetic field which induces a voltage in the sensor coil. The signal processing unit uses the induced voltage to calculate the position and orientation of the distal end portion or tip of the catheter in a patient's body.Type: GrantFiled: November 24, 2010Date of Patent: May 26, 2015Assignee: Medwaves, Inc.Inventors: Theodore C. Ormsby, Shen Gwo Jenn, George L. Leung
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Patent number: 8308722Abstract: A hollow coaxial cable adapted for conduction of radio frequency (RF) energy, particularly microwave energy, has a proximal end and a distal end and comprises coaxial inner and outer conductors extending substantially the entire length of the cable from the proximal end to a distal end portion of the cable with a dielectric medium disposed between the inner and outer conductors. The inner conductor comprises an elongated electrically conductive tubular member having a hollow, axially extending lumen, and the outer conductor comprises an elongated electrically conductive tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. An ablating member which delivers radio frequency energy, particularly microwave energy, to body tissue is disposed at a distal end portion of the cable.Type: GrantFiled: July 23, 2007Date of Patent: November 13, 2012Assignee: MedWaves, Inc.Inventors: Theodore C. Ormsby, George L. Leung, Gwo Jenn Shen, Peter Chu, Ming Fan Law
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Patent number: 8152799Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.Type: GrantFiled: September 8, 2010Date of Patent: April 10, 2012Assignee: Medwaves, Inc.Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Publication number: 20110130750Abstract: An RF ablation system has a hollow conductive coaxial cable comprising inner and outer coaxial tubular conductors, and an ablating member mounted at the distal end portion of the cable for delivery of radio frequency energy including microwaves to the target body tissue. The inner conductor has a central lumen and extends at least up to the ablating member. At least one electromagnetic tracking sensor coil with a magnetic core is located in the central lumen at the distal end portion of the cable, close to the distal tip of the cable, and connected to a signal processing unit. An electromagnetic field generator positioned in the vicinity of a patient undergoing treatment generates an electromagnetic field which induces a voltage in the sensor coil. The signal processing unit uses the induced voltage to calculate the position and orientation of the distal end portion or tip of the catheter in a patient's body.Type: ApplicationFiled: November 24, 2010Publication date: June 2, 2011Applicant: MEDWAVES, INC.Inventors: Theodore C. Ormsby, Shen Gwo Jenn, George L. Leung
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Publication number: 20110009858Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.Type: ApplicationFiled: September 8, 2010Publication date: January 13, 2011Applicant: MEDWAVES, INC.Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Patent number: 7815637Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.Type: GrantFiled: February 22, 2006Date of Patent: October 19, 2010Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Patent number: 7594913Abstract: A radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency (“RF”) generator for selectively generating a high frequency RF energy signal in a deployable catheter having an RF transmission line, an RF antenna mounted on the distal portion of the catheter, and a temperature sensor also mounted on a distal portion of the catheter for detecting temperature adjacent an ablation site. A control system adjusts the RF energy signal so that the detected temperature is at or close to a selected temperature setting or within a selected temperature range.Type: GrantFiled: June 30, 2006Date of Patent: September 29, 2009Assignee: Medwaves, Inc.Inventors: Theodore C. Ormsby, George L. Leung, Gwo Jenn Shen, Peter Chu, Ming Fan Law
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Publication number: 20090082762Abstract: A radio frequency energy transmission device comprises a hollow coaxial electrically conductive cable adapted for conduction of radio frequency (RF) energy, particularly microwave energy, for the ablation of biological tissue. The hollow cable has a proximal end and a distal end and comprises coaxial inner and outer conductors extending substantially the entire length of the cable from the proximal end to a distal end portion of the cable. The inner conductor comprises an elongated electrically conductive tubular member having a hollow, axially extending lumen, and the outer conductor comprises an elongated electrically conductive tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. Dielectricity to impede conduction between the inner and outer conductors is introduced with a vacuum or dielectric medium disposed between the inner and outer conductors.Type: ApplicationFiled: September 20, 2007Publication date: March 26, 2009Inventors: Theodore C. Ormsby, George L. Leung, Ming Fan Law
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Patent number: 7070595Abstract: A method for biological tissue ablation includes shaping a shapeable RF antenna to accommodate the contour of a body vessel adjacent a biological tissue load; generating a train of radio frequency (RF) energy pulses at an output frequency for transmission in a transmission line to the shapeable RF antenna adjacent the biological tissue load; sensing a reflected signal and a forward signal of the RF energy pulses; and adjusting output frequency of the RF energy pulses to effect a substantial match of transmission line impedance with shapeable RF antenna and biological tissue load impedance.Type: GrantFiled: August 8, 2003Date of Patent: July 4, 2006Assignee: Medwaves, Inc.Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Patent number: 7004938Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.Type: GrantFiled: November 27, 2002Date of Patent: February 28, 2006Assignee: MedWaves, Inc.Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Patent number: 6941953Abstract: A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.Type: GrantFiled: February 6, 2004Date of Patent: September 13, 2005Assignee: Medwaves, Inc.Inventors: Gregory K. Feld, Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Publication number: 20040167510Abstract: A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.Type: ApplicationFiled: February 6, 2004Publication date: August 26, 2004Applicant: Medwaves, Inc.Inventors: Gregory K. Feld, Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Publication number: 20040106917Abstract: An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency (“RF”) generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed. The RF generator having variable output frequency is adapted to generate and communicate RF energy to the RF antenna that minimizes reflected energy from the antenna-tissue interface. In application, the RF antenna establishes line of contact with the body vessel conformable to its internal contour to prescribe the precise tissue ablation pathway despite body vessel movements.Type: ApplicationFiled: August 8, 2003Publication date: June 3, 2004Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Patent number: 6663625Abstract: An improved radio-frequency catheter system for ablating biological tissues of a body vessel in a patient including a catheter, a deployable antenna guide disposed at the distal portion of the catheter and a radio-frequency (“RF”) antenna mounted on the antenna guide. The RF antenna includes a axial passageway to accommodate the antenna guide, and is adapted to receive and transmit RF energy for tissue ablation. Upon deployment, the antenna guide acquires a loop configuration which establishes line contact with the body vessel conformable to its internal contour to prescribe the precise and affixed tissue ablation pathway despite body vessel movements. The RF antenna is carried by the antenna guide to be deployed along the established tissue ablation pathway. Alignment of the loop with the desired tissue ablation pathway is facilitated with the use of radio-opaque markers and intracardiac electrodes mounted along the antenna guide.Type: GrantFiled: December 11, 1999Date of Patent: December 16, 2003Inventors: Theodore C. Ormsby, George L. Leung, Ming-Fan Law
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Publication number: 20030114844Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.Type: ApplicationFiled: November 27, 2002Publication date: June 19, 2003Applicant: Medwaves, Inc.Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
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Patent number: 6190382Abstract: An improved radio-frequency catheter system for ablating biological tissues of a body vessel in a patient including a catheter, a deployable antenna guide disposed at the distal portion of the catheter and a radio-frequency (“RF”) antenna mounted on the antenna guide. The RF antenna includes a helical coil which defines an axial passageway to accommodate the antenna guide, and is adapted to receive and transmit RF energy for tissue ablation. Upon deployment, the antenna guide acquires a loop configuration which establishes line contact with the body vessel conformable to its internal contour to prescribe the precise and affixed tissue ablation pathway despite body vessel movements. The RF antenna is carried by the antenna guide to be deployed along the established tissue ablation pathway. Alignment of the loop with the desired tissue ablation pathway is facilitated with the use of radio-opaque markers and intracardiac electrodes mounted along the antenna guide.Type: GrantFiled: December 14, 1998Date of Patent: February 20, 2001Assignee: Medwaves, Inc.Inventors: Theodore C. Ormsby, George L. Leung, Ming-Fan Law