Patents by Inventor George Lange

George Lange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11848107
    Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: December 19, 2023
    Assignee: Tempus Labs, Inc.
    Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
  • Publication number: 20220148736
    Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.
    Type: Application
    Filed: December 21, 2021
    Publication date: May 12, 2022
    Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
  • Patent number: 11244763
    Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: February 8, 2022
    Assignee: Tempus Labs, Inc.
    Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
  • Publication number: 20210343419
    Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.
    Type: Application
    Filed: July 12, 2021
    Publication date: November 4, 2021
    Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
  • Publication number: 20210319906
    Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.
    Type: Application
    Filed: April 9, 2021
    Publication date: October 14, 2021
    Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
  • Patent number: 11145416
    Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: October 12, 2021
    Assignee: Tempus Labs, Inc.
    Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
  • Patent number: 7786051
    Abstract: A method of treating a formation penetrated by a wellbore to reduce fluid loss to the formation is carried out by providing a quantity of water-degradable particles formed from a solid polymeric acid precursor having a number average molecular weight (Mn) of greater than 4000. A slurry of the particles is formed with a carrier fluid, which may be an aqueous fluid. The slurry is introduced into the formation through the wellbore at a pressure below the fracture pressure of the treated formation. A treating fluid is subsequently introduced into the formation through the wellbore. The water-degradable particles degrade by contacting the particles with a free aqueous fluid introduced into the formation through the wellbore. The water-degradable particles may have a particle size of from about 0.25 mm or less. The slurry may contain from about 0.01 kg/L to about 0.15 kg/L of the water degradable particles.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: August 31, 2010
    Assignee: Schlumberger Technology Corporation
    Inventors: George Lange, Vibhas J. Pandey, Samih Alsyed, Timothy Lesko
  • Patent number: 7382600
    Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connect to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.
    Type: Grant
    Filed: September 19, 2005
    Date of Patent: June 3, 2008
    Assignee: CAP-XX Limited
    Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
  • Patent number: 7091701
    Abstract: A power supply is for an electrical load in the form of a Notebook computer. The power supply includes first terminals which extend from the computer for releasably electrically connecting with a first energy storage device in the form of a battery during a first interval. A second energy storage device, in the form a second battery, releasably electrically connects with terminals during a second interval spaced apart from the first interval. This allows power to be supplied to the load during those intervals. A capacitive energy storage device supplies power to the load during a third interval that spans the spacing between the first and the second intervals.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: August 15, 2006
    Assignee: Energy Storage Systems PTY LTD
    Inventors: Geoffrey Alan Turner, Sarkis Keshishian, George Lange Paul
  • Patent number: 7009833
    Abstract: A charge storage device comprising: a first electrode, a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: March 7, 2006
    Assignee: Energy Storage Systems Pty. Ltd.
    Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
  • Patent number: 6998822
    Abstract: A power supply (1) for a pulsed load (2) includes a first energy storage device in the form of a battery (3) which is in parallel with a second energy storage device in the form of a supercapacitor (4). Battery (3) and supercapacitor (4) are respectively modelled as: an ideal battery (7) in series with an internal resistance (8); and an ideal capacitor (9) in series with an equivalent series resistance (ESR) (10). Through use of a supercapacitor (4) having a low ESR with respect to the resistance (8), the power supply (1) facilitates continuity of supply to load (2). That is, during peak demand more of the load current will be supplied by supercapacitor (4) due to the lower ESR. Moreover, during times of lower load current demands the battery recharges the supercapacitor. This reduces the peak current needed to be provided by the battery and thereby improves battery longevity.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: February 14, 2006
    Assignee: Energy Storage Systems PTY LTD
    Inventors: Geoffrey Alan Turner, George Lange Paul, Sarkis Keshishian, Peter John Mahon
  • Patent number: 6944010
    Abstract: A charge storage device (1) includes a sealed prismatic housing (2). Two opposed folded rectangular aluminium electrodes (3, 4) are disposed within housing (2) and connected to respective metal terminals (5, 6) for allowing external electrical connection to the electrodes. A porous, electronically insulating separator material, e.g. Soluporâ„¢, sheet separator (7) is disposed intermediate electrodes (3, 4) for maintaining those electrodes in a fixed spaced apart configuration. An electrolyte (not shown) is also disposed intermediate the electrodes. Collecting means in the form of a scavenging agent is grafted to separator (7) for sequestering one or more predetermined contaminants from the housing.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: September 13, 2005
    Assignee: Energy Storage Systems PTY Ltd.
    Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Sarkis Keshishian
  • Patent number: 6920034
    Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: July 19, 2005
    Assignee: Energy Storage Systems PTY LTD
    Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
  • Patent number: 6847192
    Abstract: A power supply (1) is for an electrical load in the form of a Notebook computer (2). Power supply (1) includes first terminals (3, 4) which extend from computer (2) for releasably electrically connecting with a first energy storage device in the form of battery (5) during a first interval. A second energy storage device, in the form a second battery (not shown), releaseably electrically connects with terminals (3, 4) during a second interval spaced apart from the first interval. This allows power to be supplied to the load during those intervals. A capacitive energy storage device, designated generally by reference numeral (6), supplies power to the load during a third interval that spans the spacing between the first and the second intervals.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: January 25, 2005
    Assignee: Energy Storage Systems Pty Ltd
    Inventors: Geoffrey Alan Turner, Sarkis Keshishian, George Lange Paul
  • Patent number: 6836097
    Abstract: A power supply (1) for a pulsed load (2) includes a first energy storage device in the form of a battery (3) which is in parallel with a second energy storage device in the form of a supercapacitor (4). Battery (3) and supercapacitor (4) are respectively modelled as: an ideal battery (7) in series with an internal resistance (8); and an ideal capacitor (9) in series with an equivalent series resistance (ESR) (10). Through use of a supercapacitor (4) having a low ESR with respect to the resistance (8), the power supply (1) facilitates continuity of supply to load (2). That is, during peak demand more of the load current will be supplied by supercapacitor (4) due to the lower ESR. Moreover, during times of lower load current demands the battery recharges the supercapacitor. This reduces the peak current needed to be provided by the battery and thereby improves battery longevity.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: December 28, 2004
    Assignee: Energy Storage Systems PTY LTD
    Inventors: Geoffrey Alan Turner, George Lange Paul, Sarkis Keshishian, Peter John Mahon
  • Publication number: 20040095098
    Abstract: A power supply (1) for a pulsed load (2) includes a first energy storage device in the form of a battery (3) which is in parallel with a second energy storage device in the form of a supercapacitor (4). Battery (3) and supercapacitor (4) are respectively modelled as: an ideal battery (7) in series with an internal resistance (8); and an ideal capacitor (9) in series with an equivalent series resistance (ESR) (10). Through use of a supercapacitor (4) having a low ESR with respect to the resistance (8), the power supply (1) facilitates continuity of supply to load (2). That is, during peak demand more of the load current will be supplied by supercapacitor (4) due to the lower ESR. Moreover, during times of lower load current demands the battery recharges the supercapacitor. This reduces the peak current needed to be provided by the battery and thereby improves battery longevity.
    Type: Application
    Filed: April 10, 2003
    Publication date: May 20, 2004
    Inventors: Geoffrey Alan Turner, George Lange Paul, Sarkis Keshishian, Peter John Mahon
  • Publication number: 20040032698
    Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.
    Type: Application
    Filed: August 7, 2003
    Publication date: February 19, 2004
    Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
  • Patent number: 6631072
    Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: October 7, 2003
    Assignee: Energy Storage Systems PTY LTD
    Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
  • Publication number: 20030169022
    Abstract: A power supply (1) is for an electrical load in the form of a notebook computer (2). Power supply (1) includes first terminals (3, 4) which extend from computer (2) for releasably electrically connecting with a first energy storage device in the form of battery (5) during a first interval. A second energy storage device, in the form a second battery (not shown), releaseably electrically connects with terminals (3, 4) during a second interval spaced apart from the first interval. This allows power to be supplied to the load during those intervals. A capacitive energy storage device, designated generally by reference numeral (6), supplies power to the load during a third interval that spans the spacing between the first and the second intervals.
    Type: Application
    Filed: May 1, 2003
    Publication date: September 11, 2003
    Inventors: Geoffrey Alan Turner, Sarkis Keshishian, George Lange Paul
  • Patent number: 6479931
    Abstract: An extended temperature operating range low pressure discharge lamp (10) including: an envelope (12) containing an ionizable medium (20) at a selected pressure; an electrode (16, 18) sealed at each end of the envelope (12) for sustaining an electric discharge through the ionizable medium; and a volume variation control for varying the volume of the ionizable medium (20) in response in variations in temperature within the envelope, wherein the volume variation control includes at least one control volume (of gaseous pressure 40) containing a specified volume of the ionizable medium and an aperture (34) communicating between the envelope (12) and the at least one control volume, wherein the at least one control volume includes a sliding piston (36) for varying the volume of the ionizable medium (20) within the envelope (12).
    Type: Grant
    Filed: June 4, 1996
    Date of Patent: November 12, 2002
    Assignee: Lockheed Martin Corporation
    Inventors: Gerhard George Lange, Robert Joseph Komar, David Luverne Vos