Patents by Inventor George Lange
George Lange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11848107Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: GrantFiled: December 21, 2021Date of Patent: December 19, 2023Assignee: Tempus Labs, Inc.Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Publication number: 20220148736Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: ApplicationFiled: December 21, 2021Publication date: May 12, 2022Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Patent number: 11244763Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: GrantFiled: July 12, 2021Date of Patent: February 8, 2022Assignee: Tempus Labs, Inc.Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Publication number: 20210343419Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: ApplicationFiled: July 12, 2021Publication date: November 4, 2021Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Publication number: 20210319906Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: ApplicationFiled: April 9, 2021Publication date: October 14, 2021Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Patent number: 11145416Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: GrantFiled: April 9, 2021Date of Patent: October 12, 2021Assignee: Tempus Labs, Inc.Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Patent number: 7786051Abstract: A method of treating a formation penetrated by a wellbore to reduce fluid loss to the formation is carried out by providing a quantity of water-degradable particles formed from a solid polymeric acid precursor having a number average molecular weight (Mn) of greater than 4000. A slurry of the particles is formed with a carrier fluid, which may be an aqueous fluid. The slurry is introduced into the formation through the wellbore at a pressure below the fracture pressure of the treated formation. A treating fluid is subsequently introduced into the formation through the wellbore. The water-degradable particles degrade by contacting the particles with a free aqueous fluid introduced into the formation through the wellbore. The water-degradable particles may have a particle size of from about 0.25 mm or less. The slurry may contain from about 0.01 kg/L to about 0.15 kg/L of the water degradable particles.Type: GrantFiled: December 7, 2006Date of Patent: August 31, 2010Assignee: Schlumberger Technology CorporationInventors: George Lange, Vibhas J. Pandey, Samih Alsyed, Timothy Lesko
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Patent number: 7382600Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connect to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.Type: GrantFiled: September 19, 2005Date of Patent: June 3, 2008Assignee: CAP-XX LimitedInventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
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Patent number: 7091701Abstract: A power supply is for an electrical load in the form of a Notebook computer. The power supply includes first terminals which extend from the computer for releasably electrically connecting with a first energy storage device in the form of a battery during a first interval. A second energy storage device, in the form a second battery, releasably electrically connects with terminals during a second interval spaced apart from the first interval. This allows power to be supplied to the load during those intervals. A capacitive energy storage device supplies power to the load during a third interval that spans the spacing between the first and the second intervals.Type: GrantFiled: November 15, 2004Date of Patent: August 15, 2006Assignee: Energy Storage Systems PTY LTDInventors: Geoffrey Alan Turner, Sarkis Keshishian, George Lange Paul
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Patent number: 7009833Abstract: A charge storage device comprising: a first electrode, a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.Type: GrantFiled: February 7, 2005Date of Patent: March 7, 2006Assignee: Energy Storage Systems Pty. Ltd.Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
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Patent number: 6998822Abstract: A power supply (1) for a pulsed load (2) includes a first energy storage device in the form of a battery (3) which is in parallel with a second energy storage device in the form of a supercapacitor (4). Battery (3) and supercapacitor (4) are respectively modelled as: an ideal battery (7) in series with an internal resistance (8); and an ideal capacitor (9) in series with an equivalent series resistance (ESR) (10). Through use of a supercapacitor (4) having a low ESR with respect to the resistance (8), the power supply (1) facilitates continuity of supply to load (2). That is, during peak demand more of the load current will be supplied by supercapacitor (4) due to the lower ESR. Moreover, during times of lower load current demands the battery recharges the supercapacitor. This reduces the peak current needed to be provided by the battery and thereby improves battery longevity.Type: GrantFiled: October 21, 2004Date of Patent: February 14, 2006Assignee: Energy Storage Systems PTY LTDInventors: Geoffrey Alan Turner, George Lange Paul, Sarkis Keshishian, Peter John Mahon
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Patent number: 6944010Abstract: A charge storage device (1) includes a sealed prismatic housing (2). Two opposed folded rectangular aluminium electrodes (3, 4) are disposed within housing (2) and connected to respective metal terminals (5, 6) for allowing external electrical connection to the electrodes. A porous, electronically insulating separator material, e.g. Soluporâ„¢, sheet separator (7) is disposed intermediate electrodes (3, 4) for maintaining those electrodes in a fixed spaced apart configuration. An electrolyte (not shown) is also disposed intermediate the electrodes. Collecting means in the form of a scavenging agent is grafted to separator (7) for sequestering one or more predetermined contaminants from the housing.Type: GrantFiled: August 30, 2000Date of Patent: September 13, 2005Assignee: Energy Storage Systems PTY Ltd.Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Sarkis Keshishian
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Patent number: 6920034Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.Type: GrantFiled: August 7, 2003Date of Patent: July 19, 2005Assignee: Energy Storage Systems PTY LTDInventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
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Patent number: 6847192Abstract: A power supply (1) is for an electrical load in the form of a Notebook computer (2). Power supply (1) includes first terminals (3, 4) which extend from computer (2) for releasably electrically connecting with a first energy storage device in the form of battery (5) during a first interval. A second energy storage device, in the form a second battery (not shown), releaseably electrically connects with terminals (3, 4) during a second interval spaced apart from the first interval. This allows power to be supplied to the load during those intervals. A capacitive energy storage device, designated generally by reference numeral (6), supplies power to the load during a third interval that spans the spacing between the first and the second intervals.Type: GrantFiled: May 15, 2001Date of Patent: January 25, 2005Assignee: Energy Storage Systems Pty LtdInventors: Geoffrey Alan Turner, Sarkis Keshishian, George Lange Paul
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Patent number: 6836097Abstract: A power supply (1) for a pulsed load (2) includes a first energy storage device in the form of a battery (3) which is in parallel with a second energy storage device in the form of a supercapacitor (4). Battery (3) and supercapacitor (4) are respectively modelled as: an ideal battery (7) in series with an internal resistance (8); and an ideal capacitor (9) in series with an equivalent series resistance (ESR) (10). Through use of a supercapacitor (4) having a low ESR with respect to the resistance (8), the power supply (1) facilitates continuity of supply to load (2). That is, during peak demand more of the load current will be supplied by supercapacitor (4) due to the lower ESR. Moreover, during times of lower load current demands the battery recharges the supercapacitor. This reduces the peak current needed to be provided by the battery and thereby improves battery longevity.Type: GrantFiled: April 10, 2003Date of Patent: December 28, 2004Assignee: Energy Storage Systems PTY LTDInventors: Geoffrey Alan Turner, George Lange Paul, Sarkis Keshishian, Peter John Mahon
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Publication number: 20040095098Abstract: A power supply (1) for a pulsed load (2) includes a first energy storage device in the form of a battery (3) which is in parallel with a second energy storage device in the form of a supercapacitor (4). Battery (3) and supercapacitor (4) are respectively modelled as: an ideal battery (7) in series with an internal resistance (8); and an ideal capacitor (9) in series with an equivalent series resistance (ESR) (10). Through use of a supercapacitor (4) having a low ESR with respect to the resistance (8), the power supply (1) facilitates continuity of supply to load (2). That is, during peak demand more of the load current will be supplied by supercapacitor (4) due to the lower ESR. Moreover, during times of lower load current demands the battery recharges the supercapacitor. This reduces the peak current needed to be provided by the battery and thereby improves battery longevity.Type: ApplicationFiled: April 10, 2003Publication date: May 20, 2004Inventors: Geoffrey Alan Turner, George Lange Paul, Sarkis Keshishian, Peter John Mahon
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Publication number: 20040032698Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.Type: ApplicationFiled: August 7, 2003Publication date: February 19, 2004Inventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
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Patent number: 6631072Abstract: A charge storage device comprising: a first electrode; a second electrode being opposed to and spaced apart from the first electrode; a porous separator disposed between the electrodes; a sealed package for containing the electrodes, the separator and an electrolyte in which the electrodes are immersed; and a first terminal and a second terminal being electrically connected to the first electrode and the second electrode respectively and both extending from the package to allow external electrical connection to the respective electrodes, wherein the gravimetric FOM of the device is greater than about 2.1 Watts/gram.Type: GrantFiled: August 24, 2001Date of Patent: October 7, 2003Assignee: Energy Storage Systems PTY LTDInventors: George Lange Paul, Rory Albert James Pynenburg, Peter John Mahon, Anthony Michael Vassallo, Philip Andrew Jones, Sarkis Keshishian, Anthony Gaetano Pandolfo
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Publication number: 20030169022Abstract: A power supply (1) is for an electrical load in the form of a notebook computer (2). Power supply (1) includes first terminals (3, 4) which extend from computer (2) for releasably electrically connecting with a first energy storage device in the form of battery (5) during a first interval. A second energy storage device, in the form a second battery (not shown), releaseably electrically connects with terminals (3, 4) during a second interval spaced apart from the first interval. This allows power to be supplied to the load during those intervals. A capacitive energy storage device, designated generally by reference numeral (6), supplies power to the load during a third interval that spans the spacing between the first and the second intervals.Type: ApplicationFiled: May 1, 2003Publication date: September 11, 2003Inventors: Geoffrey Alan Turner, Sarkis Keshishian, George Lange Paul
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Patent number: 6479931Abstract: An extended temperature operating range low pressure discharge lamp (10) including: an envelope (12) containing an ionizable medium (20) at a selected pressure; an electrode (16, 18) sealed at each end of the envelope (12) for sustaining an electric discharge through the ionizable medium; and a volume variation control for varying the volume of the ionizable medium (20) in response in variations in temperature within the envelope, wherein the volume variation control includes at least one control volume (of gaseous pressure 40) containing a specified volume of the ionizable medium and an aperture (34) communicating between the envelope (12) and the at least one control volume, wherein the at least one control volume includes a sliding piston (36) for varying the volume of the ionizable medium (20) within the envelope (12).Type: GrantFiled: June 4, 1996Date of Patent: November 12, 2002Assignee: Lockheed Martin CorporationInventors: Gerhard George Lange, Robert Joseph Komar, David Luverne Vos