Patents by Inventor George M. Yousef

George M. Yousef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210147944
    Abstract: The present disclosure provides methods for monitoring prostate cancer by determining or measuring exosomal miRNA levels in a biological sample to provide a biological sample exosomal miRNA profile comprising exosomal miRNA levels and determining or measuring the level of similarity of said biological sample exosomal miRNA profile to one or more control profiles. The present disclosure also provides kits for monitoring prostate cancer progression and methods for selecting a treatment for prostate cancer.
    Type: Application
    Filed: April 10, 2019
    Publication date: May 20, 2021
    Inventors: George M. Yousef, Neil Eric Fleshner
  • Publication number: 20120251451
    Abstract: The invention provides markers for renal cancer, polynucleotides encoding same, and precursors thereof. The invention also provides methods for detecting, diagnosing, screening for, monitoring, assessing, and treating renal cancers and related disease conditions in a subject. The invention further provides a method of selecting for or assessing efficacy of agents against renal cancer, and a method for assessing renal cancer cell carcinogenic potential of a compound. The invention further provides localization and imaging methods for renal cancers. Also provided are diagnostic compositions and kits for carrying out methods of the invention. In addition, the invention provides therapeutic applications for renal cancers which employ protein renal cancer markers and polynucleotides encoding same, miRNA renal cancer markers and precursors thereof, and binding agents for the markers.
    Type: Application
    Filed: December 19, 2011
    Publication date: October 4, 2012
    Inventors: K.W. Michael SIU, Leroi V. Desouza, George M. Yousef, Alexander D. Romaschin
  • Patent number: 7507403
    Abstract: The invention relates to a kallikrein protein, compositions comprising the protein, and the use thereof.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: March 24, 2009
    Assignee: Mount Sinai Hospital
    Inventors: George M. Yousef, Eleftherios P. Diamandis
  • Patent number: 7199229
    Abstract: The present invention relates to nucleic acid molecules, encoding kallikrein 15, a novel member of the kallikrein family. Also provided herein are vectors and host cells comprising the nucleic acid molecules, and methods for producing kallikrein 15 proteins.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: April 3, 2007
    Assignee: Mount Sinai Hospital
    Inventors: George M. Yousef, Eleftherios P. Diamandis
  • Patent number: 7022497
    Abstract: The invention relates to nucleic acid molecules, kallikrein-like proteins encoded by such nucleic acid molecules; and use of the proteins and nucleic acid molecules.
    Type: Grant
    Filed: March 9, 2000
    Date of Patent: April 4, 2006
    Assignee: Mt. Sinai Hospital
    Inventors: George M. Yousef, Eleftherios P. Diamandis
  • Publication number: 20040058342
    Abstract: The invention relates to nucleic acid molecules. proteins encoded by such nucleic acid molecules: and use of the proteins and nucleic acid molecule.
    Type: Application
    Filed: August 1, 2003
    Publication date: March 25, 2004
    Inventors: George M Yousef, Eleftherios P Diamandis