Abstract: This document presents a system and method for analyzing migraine related sensor and diary data to permit the prediction of migraine headaches for individuals. A mobile device is adapted to collect and transmit to a server data content from sensors associated with the mobile device and self-reported data content indicative of contemporaneous environmental conditions and individual physical conditions when the individual is suffering from a migraine headache. The server uses the data content to develop predictive metrics indicative of a correlation between the migraine events and the sensor data. The predictive metrics will provide an alert to a designated individual if it is likely the individual will experience a migraine within a future time period.

Abstract: This document presents a system and method for analyzing migraine related sensor and diary data to permit the prediction of migraine headaches for individuals. A mobile device is adapted to collect and transmit to a server data content from sensors associated with the mobile device and self-reported data content indicative of contemporaneous environmental conditions and individual physical conditions when the individual is suffering from a migraine headache. The server uses the data content to develop predictive metrics indicative of a correlation between the migraine events and the sensor data. The predictive metrics will provide an alert to a designated individual if it is likely the individual will experience a migraine within a future time period.

Abstract: This document presents a system and method for analyzing migraine related sensor and diary data to permit the prediction of migraine headaches for individuals. A mobile device is adapted to collect and transmit to a server data content from sensors associated with the mobile device and self-reported data content indicative of contemporaneous environmental conditions and individual physical conditions when the individual is suffering from a migraine headache. The server uses the data content to develop predictive metrics indicative of a correlation between the migraine events and the sensor data. The predictive metrics will provide an alert to a designated individual if it is likely the individual will experience a migraine within a future time period.

Abstract: This document presents a system and method for analyzing migraine related sensor and diary data to permit the prediction of migraine headaches for individuals. A mobile device is adapted to collect and transmit to a server data content from sensors associated with the mobile device and self-reported data content indicative of contemporaneous environmental conditions and individual physical conditions when the individual is suffering from a migraine headache. The server uses the data content to develop predictive metrics indicative of a correlation between the migraine events and the sensor data. The predictive metrics will provide an alert to a designated individual if it is likely the individual will experience a migraine within a future time period.

Abstract: The present invention provides a method of treating a disorder associated with muscle weakness in a subject, comprising administering to the subject a controlled-release composition comprising an effective amount of ribitol and/or ribose, thereby treating the disorder associated with muscle weakness.

Abstract: Disclosed herein are platforms and methods for collecting migraine associated data. Migraine associated data is collected automatically, such as via a sensor, or is self-reported manually.

Abstract: Disclosed herein are platforms and methods for collecting migraine associated data. Migraine associated data is collected automatically, such as via a sensor, or is self-reported manually.

Abstract: Compounds that bind cellular IAPs (inhibitor of apoptosis proteins) are disclosed. The compounds are mimetics of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABOLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these compounds for therapeutic, diagnostic and assay purposes.

Abstract: Compounds that bind cellular IAPs (inhibitor of apoptosis proteins) are disclosed. The compounds are mimetics of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABOLO, IIid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these compounds for therapeutic, diagnostic and assay purposes.

Abstract: Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrates, e.g., well plates formed from a material that is at least partially nonmetallic or polymeric and either has an electrical resistivity of no more than about 1011 ohm-cm, has a surface electrical resistivity of no more than about 1012 ohm/sq, or both.

Abstract: Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrates, e.g., well plates formed from a material that is at least partially nonmetallic or polymeric and either has an electrical resistivity of no more than about 1011 ohm-cm, has a surface electrical resistivity of no more than about 1012 ohm/sq, or both.

Abstract: Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrates, e.g., well plates formed from a material that is at least partially nonmetallic or polymeric and either has an electrical resistivity of no more than about 1011 ohm-cm, has a surface electrical resistivity of no more than about 1012 ohm/sq, or both.

Abstract: Compounds that bind cellular IAPs (inhibitor of apoptosis proteins) are disclosed. The compounds are mimetics of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABOLO, IIid. Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these compounds for therapeutic, diagnostic and assay purposes.

Abstract: Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrates, e.g., well plates formed from a material that is at least partially nonmetallic or polymeric and either has an electrical resistivity of no more than about 1011 ohm-cm, has a surface electrical resistivity of no more than about 1012 ohm/sq, or both.

Abstract: Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrates, e.g., well plates formed from a material that is at least partially nonmetallic or polymeric and either has an electrical resistivity of no more than about 1011 ohm-cm, has a surface electrical resistivity of no more than about 1012 ohm/sq, or both.

Abstract: Assays are disclosed for identifying peptides and peptidomimetics for promoting apotosis in cells, through a pathway involving the Inhibitor of Apoptosis Proteins (IAPs), exemplified by XIAP, and the mitochondrial protein Smac/DIABOLO (hereinafter Smac) and homologs thereof. Also disclosed are IAP-binding peptides and peptidomimetics identified through the use of the assay.

Abstract: Devices and methods are provided for reducing the uncontrolled electrostatic charges that can alter the volume and/or trajectory of a droplet, which is typically ejected through the application of focused acoustic radiation. Also provided are reservoirs and substrates, e.g., well plates formed from a material that is at least partially nonmetallic or polymeric and either has an electrical resistivity of no more than about 1011 ohm-cm, has a surface electrical resistivity of no more than about 1012 ohm/sq, or both.