Patents by Inventor George Michael Blackburn

George Michael Blackburn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza virus neuraminidase crystal structure and their use thereof
    Publication number: 20090265114
    Abstract: The invention relates to crystals of the influenza virus neuraminidase protein, their structures and their use.
    Type: Application
    Filed: June 6, 2007
    Publication date: October 22, 2009
    Inventors: Steven John Gamblin, Alan James Hay, John James Skehel, Lesley Findlay Haire, David John Stevens, Rupert Russell, Patrick James Collins, Yi Pu Lin, George Michael Blackburn
  • Catalytic antibodies for carbamate activation by a non-spontaneous reaction mechanism
    Patent number: 5807688
    Abstract: Catalytic antibodies capable of catalysing activation of a carbamate (--O--CO--NH--) containing prodrug suitable for Antibody Directed Abzyme Prodrug Therapy (ADAPT) by catalysing breakdown of the prodrug at the carbamate position by a non-spontaneous reaction mechanism. The non-spontaneous reaction preferably has a B.sub.Ac 2 mechanism and the prodrug is a preferably a nitrogen mustard aryl carbamate. The invention also includes relevant immunogens, screens for catalytic activity using short transition state analogues and ADAPT systems.
    Type: Grant
    Filed: May 24, 1996
    Date of Patent: September 15, 1998
    Assignee: Zeneca Limited
    Inventors: George Michael Blackburn, Paul Wentworth