Patents by Inventor George Mooney

George Mooney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating a patient afflicted with non-alcoholic steatohepatitis (NASH)
    Patent number: 11865113
    Abstract: Pharmaceutical carriers which provide an environment of physical and chemical stability comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound of structure I, one or more antioxidants, one or more chelators and a vehicle base comprising water and one or more pharmaceutically acceptable non-aqueous solvents, one or more absorption enhancers, one or more gelling agents and one or more pH buffering agents are described.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: January 9, 2024
    Assignee: LIPIDIO PHARMACEUTICALS INC.
    Inventors: Nigel R. A. Beeley, J. Gordon Foulkes, Kieran George Mooney, Charles Rodney Greenaway Evans, Keith Arthur Johnson, Howard G. Welgus, Celia P. Jenkinson
  • MODIFIED RELEASE FORMULATIONS OF MODIFIED FORMS OF TRIMETAZIDINE
    Publication number: 20210401834
    Abstract: The invention provides pharmaceutical compositions that contain modified release formulations of modified forms of trimetazidine, such as CV-8972. The compositions include an erodible polymer, such as hydroxypropyl methylcellulose (HPMC), that allows sustained release of the modified form of trimetazidine and it metabolic products in the body. The invention also provides methods of treating conditions, including angina and heart failure, using such compositions.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 30, 2021
    Inventors: George Mooney, Scott Herbig
  • MODIFIED RELEASE FORMULATIONS OF MODIFIED FORMS OF TRIMETAZIDINE
    Publication number: 20210401833
    Abstract: The invention provides pharmaceutical compositions that contain modified release formulations of modified forms of trimetazidine, such as CV-8972. The compositions include an erodible polymer, such as hydroxypropyl methylcellulose (HPMC), that allows sustained release of the modified form of trimetazidine and it metabolic products in the body. The invention also provides methods of treating conditions, including angina and heart failure, using such compositions.
    Type: Application
    Filed: June 28, 2021
    Publication date: December 30, 2021
    Inventors: Andrew D. Levin, Jaikrishna Patel, George Mooney
  • FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME
    Publication number: 20200306248
    Abstract: Pharmaceutical carriers which provide an environment of physical and chemical stability comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound of structure I, one or more antioxidants, one or more chelators and a vehicle base comprising water and one or more pharmaceutically acceptable non-aqueous solvents, one or more absorption enhancers, one or more gelling agents and one or more pH buffering agents are described.
    Type: Application
    Filed: June 6, 2017
    Publication date: October 1, 2020
    Applicant: GDD Therapeutics, LLC
    Inventors: Nigel R.A. Beeley, J. Gordon Foulkes, Kieran George Mooney, Charles Rodney Greenaway Evans, Keith Arthur Johnson, Howard G. Welgus, Celia P. Jenkinson, James R. Hauske
  • METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
    Publication number: 20180296630
    Abstract: The disclosure provides methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof. More specifically, the disclosure provides a composition for preventing, treating, or ameliorating the symptoms of diabetic macular edema in a mammalian subject in need thereof, comprising: a therapeutically effective amount of a peptide D-Arg-2?6?-Dmt-Lys-Phe-NH2 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 29, 2017
    Publication date: October 18, 2018
    Inventors: D. Travis Wilson, K. George Mooney, Peter J. Oates
  • METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
    Publication number: 20160361377
    Abstract: The disclosure provides methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof. More specifically, the disclosure provides a composition for preventing, treating, or ameliorating the symptoms of diabetic macular edema in a mammalian subject in need thereof, comprising: a therapeutically effective amount of a peptide D-Arg-2?6?-Dmt-Lys-Phe-NH2 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 7, 2016
    Publication date: December 15, 2016
    Inventors: D. Travis Wilson, K. George Mooney, Peter J. Oates
  • METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
    Publication number: 20150018288
    Abstract: The disclosure provides methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof. More specifically, the disclosure provides a composition for preventing, treating, or ameliorating the symptoms of diabetic macular edema in a mammalian subject in need thereof, comprising: a therapeutically effective amount of a peptide D-Arg-2?6?-Dmt-Lys-Phe-NH2 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 21, 2013
    Publication date: January 15, 2015
    Applicant: Stealth Peptides International, Inc.
    Inventors: D. Travis Wilson, K. George Mooney, Peter J. Oates
  • Frictionless linear actuator
    Patent number: 5221845
    Abstract: A device for positioning a target in the beam of a particle accelerator, which comprises a means for pivoting the actuator shaft within ultra high vacuum without sliding friction. The invention also comprises a means for removing the drive mechanism without releasing the vacuum, which simplifies the baking process, the invention also offers a simplified adjustment procedure, a lower profile, and a tamper proof cover.
    Type: Grant
    Filed: December 16, 1991
    Date of Patent: June 22, 1993
    Assignee: George Mooney
    Inventor: George Mooney