Patents by Inventor George P. Lampson

George P. Lampson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Herpes simplex type I subunit vaccine
    Patent number: 4540669
    Abstract: A herpes simplex type I subunit vaccine is prepared from infected chick embryo cells by ultra extraction of the virus while the infected cells are still attached to the growth surface.
    Type: Grant
    Filed: July 23, 1981
    Date of Patent: September 10, 1985
    Assignee: Merck & Co., Inc.
    Inventors: Alexander U. Bertland, George P. Lampson
  • Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates
    Patent number: 4388306
    Abstract: A complex of polyriboinosinic-polyribocytidylic acid (poly I:C) with poly-L-lysine hydrobromide ([lysine.HBr].sub.n) having a defined molecular weight is prepared which is about 5-15 times as resistant to hydrolysis by pancreatic ribonuclease as the parent poly I:C. A pharmaceutical solution, containing a relatively high concentration of the complex, prepared as described, induces significant antiviral levels of serum interferon in monkeys under conditions in which poly I:C itself induces little or no interferon. An important feature of this invention is that the product is a soluble material requiring no special solubilizing agent, thereby facilitating the preparation of solutions having the desired concentration. The product will hereinafter be designated as poly I:C/poly-L-lysine.
    Type: Grant
    Filed: February 8, 1982
    Date of Patent: June 14, 1983
    Assignee: Merck & Co., Inc.
    Inventors: A. Kirk Field, Alfred A. Tytell, George P. Lampson
  • Herpes simplex type 1 subunit vaccine
    Patent number: 4317811
    Abstract: A herpes simplex type 1 subunit vaccine is prepared from infected chick embryo cells by urea-extraction of the virus while the infected cells are still attached to the growth surface.
    Type: Grant
    Filed: September 11, 1980
    Date of Patent: March 2, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Alexander U. Bertland, George P. Lampson
  • Polynucleotides active as inducers of interferon production in living animal cells
    Patent number: 4124702
    Abstract: Polynucleotides which are multistranded are active as inducers of interferon production in living animal cells. They may be:A. Synthetically complexed polymers of two homopolynucleotides.B. A nucleic acid released by phenol from a ribonucleic acid complex elaborated by the growth of Penicillium funiculosum.C. A ribonucleic acid from reovirus type 3 virions.D. Replicative forms of nucleic acids.
    Type: Grant
    Filed: December 14, 1976
    Date of Patent: November 7, 1978
    Assignee: Merck & Co., Inc.
    Inventors: George P. Lampson, Alfred A. Tytell, Arthur K. Field, Maurice R. Hilleman
  • Method for purifying hepatitis B antigen
    Patent number: 4017360
    Abstract: Hepatitis B antigen useful as vaccine is prepared from clarified plasma of hepatitis B donors by treating with pepsin at a pH wherein pepsin is enzymatically active, treating with urea, and optionally treating with formaldehyde.
    Type: Grant
    Filed: May 14, 1975
    Date of Patent: April 12, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Alexander U. Bertland, Alfred A. Tytell, George P. Lampson, Eugene Buynak