Abstract: A composition containing succinate dehydrogenase inhibitor and a potentiator has been discovered to enhance the activity of the succinate dehydrogenase such that the amount of the succinate dehydrogenase inhibitor need to effectively treat a microbial substance can be reduced substantially. The compositions may be used as additives for paints and coatings, and protecting crops, seeds, wallboard, metal working fluids, wood from mold, fungi and other microbes.

Abstract: A composition having biocidal properties is disclosed. The composition includes a first biocide, optionally a second biocide, and a biocide enhancing agent. The first biocide may comprise an isothiazolin. The second biocide may comprise a pyrithione. The biocide enhancing agent may comprise an amine, an amine salt, an amine oxide, or mixtures thereof. The amine compound may have a carbon chain length of at least six carbon atoms, such as at least eight carbon atoms.

Abstract: The present invention, therefore, is directed to an antimicrobial compositions that decreases the bioavailability of iron by introducing a higher-affinity iron-selective chelating agent capable of competing with microbial siderophores. In one aspect, the present invention relates to an antimicrobial composition including a potentiating antimicrobial composition including one or more antimicrobial agents and a chelator having a weight ratio of the antimicrobial agent to the chelator from about 1:1000 to about 1000:1.

Abstract: The present invention, therefore, is directed to an antimicrobial compositions that decreases the bioavailability of iron by introducing a higher-affinity iron-selective chelating agent capable of competing with microbial siderophores. In one aspect, the present invention relates to an antimicrobial composition including a potentiating antimicrobial composition including one or more antimicrobial agents and a chelator having a weight ratio of the antimicrobial agent to the chelator from about 1:1000 to about 1000:1.

Abstract: A composition containing succinate dehydrogenase inhibitor and a potentiator has been discovered to enhance the activity of the succinate dehydrogenase such that the amount of the succinate dehydrogenase inhibitor need to effectively treat a microbial substance can be reduced substantially. The compositions may be used as additives for paints and coatings, and protecting crops, seeds, wallboard, metal working fluids, wood from mold, fungi and other microbes.

Abstract: A composition containing succinate dehydrogenase inhibitor and a potentiator has been discovered to enhance the activity of the succinate dehydrogenase such that the amount of the succinate dehydrogenase inhibitor need to effectively treat a microbial substance can be reduced substantially. The compositions may be used as additives for paints and coatings, and protecting crops, seeds, wallboard, metal working fluids, wood from mold, fungi and other microbes.

Abstract: Building material products, particularly wallboard, are disclosed that are mold resistant. A mold inhibitory composition is contained in one component of the building material product. The mold inhibitory composition comprises a pyrithione in combination with at least one potentiator. The potentiator can comprise a metal chelate, a membrane permeabilizer, or another microorganism weakening agent.

Abstract: A composition having biocidal properties is disclosed. The composition includes a first biocide, optionally a second biocide, and a biocide enhancing agent. The first biocide may comprise an isothiazolin. The second biocide may comprise a pyrithione. The biocide enhancing agent may comprise an amine, an amine salt, an amine oxide, or mixtures thereof. The amine compound may have a carbon chain length of at least six carbon atoms, such as at least eight carbon atoms.

Abstract: A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.

Abstract: The present invention, therefore, is directed to an antimicrobial compositions that decreases the bioavailability of iron by introducing a higher-affinity iron-selective chelating agent capable of competing with microbial siderophores. In one aspect, the present invention relates to an antimicrobial composition including a potentiating antimicrobial composition including one or more antimicrobial agents and a chelator having a weight ratio of the antimicrobial agent to the chelator from about 1:1000 to about 1000:1.

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprising a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Abstract: The present invention provides a composition containing a pyrithione compound and a pyranone compound and a method of reducing discoloration of compositions containing pyrithione compounds. The composition may be a soap composition.

Abstract: The present invention is directed to a water treatment composition, comprising: calcium hypochlorite coated with a coating comprising at least one hydrated or anhydrous salt. The present invention is also directed to a water treatment composition, comprising: (a) an inner core layer comprising calcium hypochlorite; (b) one or more interlayers of selected salts positioned on top of said inner core layer, and (c) one or more outer layers of selected salts positioned on top of said interlayer(s).

Abstract: Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprising a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprision a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

Abstract: The present invention is directed to a water treatment composition, comprising: calcium hypochlorite coated with a coating comprising at least one hydrated or anhydrous salt. The present invention is also directed to a water treatment composition, comprising: (a) an inner core layer comprising calcium hypochlorite; (b) one or more interlayers of selected salts positioned on top of said inner core layer, and (c) one or more outer layers of selected salts positioned on top of said interlayer(s).

Abstract: Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.

Abstract: Disclosed are topical compositions for the treatment of microbial infections on the skin or scalp which include a polyvalent metal salt of pyrithione and include a metal ion source. Also disclosed are methods for treating microbial infections of the skin or scalp using such compositions.

Abstract: A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.