Abstract: Embodiments of an overlay network with innovative virtual network switches and related network interface controllers are disclosed. According to one embodiment, the overlay network may comprise at least one virtual network switch (VNS), wherein each VNS is installed within a corresponding first processing endpoint which is logically above a network of virtual machines. And, the VNS may be configured to intercept data packets transmitted on a network layer logically below the network of virtual machines. The VNS may comprise: (a) a manager element configured to connect to at least one virtual network interface controller (VNIC), each VNIC being installed within a corresponding second processing endpoint which is also logically above the network of virtual machines; (b) a replicator node configured to replicate and route the data packets; and (c) a switch controller configured to control the first replicator node.

Abstract: A database system operates by: generating first segment addendum data indicating at least one addendum part indicating at least one change to a first segment of a plurality of segments, updating segment part activation data to indicate a first ownership sequence number (OSN) range for activation of the first segment addendum data during query execution, executing a first query, having a first ownership sequence number, based on accessing the first segment in response to first data ownership information tagged with the first ownership sequence number indicating activation of the first segment, and further based on foregoing applying of the at least one addendum part for the first segment in response to the first ownership sequence number falling outside of the first OSN range indicated in the segment part activation data for the first segment addendum data, and executing a second query, having a second ownership sequence number, based on accessing the first segment in response to second data ownership informat

Abstract: A building system includes one or more storage devices having instructions stored thereon that, when executed by one or more processors, cause the one or more processors to receive an unstructured user question from a user device of a user and query a graph database based on the unstructured user question to extract context associated with the unstructured user question from contextual information of a building stored by the graph database, wherein the graph database stores the contextual information of the building through nodes and edges between the nodes, wherein the nodes represent equipment, spaces, people, and events associated building and the edges represent relationships between the equipment, spaces, people, and events. The instructions further cause the one or more processors to retrieve data from one or more data sources based on the context and compose a presentation based on the retrieved data.

Abstract: In some aspects, the techniques described herein relate to a semiconductor device including: a substrate having a first side and a second side, the second side being opposite the first side; active circuitry disposed on the first side of the substrate; a metallic implant disposed in the substrate, the metallic implant being a blanket implant on the second side of the substrate; and a metallic layer disposed on the second side of the substrate, the metallic layer and the second side of the substrate including the metallic implant defining an ohmic contact.

Abstract: A protection circuit for an acoustic filter and/or a power amplifier is disclosed. In one aspect, the protection circuit includes a bidirectional coupler that helps secure a measurement of power at an antenna. The power measurement is compared to a threshold by a detector, and if the power measurement is above the threshold, a signal is sent that causes debiasing of a power amplifier stage, which reduces power levels of signals being amplified by the power amplifier stage and correspondingly lowers the power level going through a filter associated with the power amplifier stage. By lowering the power level going through the power amplifier stage and the filter, both elements are protected against overpower conditions, allowing functionality to be maintained.

Abstract: Provided herein are methods for purifying an anti-?4?7 integrin antibody, such as vedolizumab, from a liquid solution, e.g., from a mammalian cell culture clarified harvest. The invention relates, inter alia, to purification methods for controlling the amount of product-related substances and/or process-related impurities present in purified preparations of an anti-?4?7 integrin antibody, or antigen-binding fragment thereof, e.g., vedolizumab. Compositions comprising an anti-?4?7 antibody, and uses thereof to treat a disorder, are also provided.

Abstract: Methods of purifying a humanized ?4?7 antibody, such as vedolizumab, produced in a mammalian cell culture are described herein, as are compositions resulting from said purification processes.

Abstract: A composition is described which comprises a component which is susceptible to free radical attack, said composition comprising, as a free radical scavenger, at least one particle having a size not exceeding 100 nm of an oxide of a rare earth or transition metal possessing adjacent oxidation states. The composition is preferable a UV sunscreen composition suitable also for cosmetic use.

Abstract: A polymeric composition is described which comprises an amount of one or more organic or inorganic components which are photosensitive and/or which are degraded by another ingredient of the composition and an amount of Ti02 and/or ZnO which has been doped with a second element or the reduced ZnO, this composition having a rate of deterioration of UV light-sensitive physical factor at least 5% less than that of a composition having the same formulation except that it does not contain the said Ti02 and/or ZnO which has been doped with a second element or the said ZnO.

Abstract: A composition is described which comprises an ingredient which is adversely affected by the presence of TiO2 and/or ZnO, and TiO2 and/or ZnO which has been doped with another element and/or reduced ZnO.

Abstract: A UV sunscreening composition suitable for cosmetic or topical pharmaceutical use which comprises an amount of one or more organic components which are photosensitive and/or which are degraded and/or in which degradation is induced by another ingredient of the composition, and an amount of TiO2 and/or ZnO which has been doped with another element and/or reduced zinc oxide, this composition having a rate of loss of UV absorption at least 5% less than that of a composition having the same formulation except that it does not contain the said TiO2 and/or ZnO which has been doped with another element or the said reduced zinc oxide.

Abstract: Centrally apertured discs which are to be subjected on one side to a treatment such as the deposition of a layer of material on the disc are carried on disc holders in a magazine which comprises a pair of opposed parallel walls and which has an open side between these walls through which the disc holders can be inserted in and removed from the magazine. The disc holders each comprise a rigid plate and attachment means for attaching a centrally apertured disc to each side of the plate, the attachment means engaging in the central aperture of each disc. The plate has at least one pair of opposed parallel edges for cooperation with guide rollers which are provided on the inner sides of the opposed walls of the magazine for guiding the disc holders during their insertion in and removal from the magazine in directions parallel to the opposed edges of the plates.