Abstract: The present disclosure is concerned with compounds, compositions, and methods for synthesizing sphingosines and glycolipids including glycosphingolipids, such as but not limited to lactosyl sphingosine.

Abstract: Embodiments of the present invention provide a controller, a system, a method and a vehicle, to receive one or more user inputs from one or more user input units; receive one or more vehicle condition inputs from one or more vehicle condition sensor units; determine if an open position of a aperture member of a vehicle is likely to cause buffeting; select an optimisation strategy from a plurality of optimisation strategies in dependence on the one or more user inputs and/or the one or more vehicle condition inputs, wherein each of the plurality of optimisation strategy comprises different instructions to determine one or more positions for at least one aperture member; and generate an output for the one or more aperture member positioning units to move at least one aperture member based on the selected optimisation strategy.

Abstract: Embodiments of the present invention provide a controller, a system, a method and a vehicle, to receive one or more user inputs from one or more user input units; receive one or more vehicle condition inputs from one or more vehicle condition sensor units; determine if an open position of a aperture member of a vehicle is likely to cause buffeting; select an optimisation strategy from a plurality of optimisation strategies in dependence on the one or more user inputs and/or the one or more vehicle condition inputs, wherein each of the plurality of optimisation strategy comprises different instructions to determine one or more positions for at least one aperture member; and generate an output for the one or more aperture member positioning units to move at least one aperture member based on the selected optimisation strategy.