Abstract: The present invention is directed to novel arginine alpha-keto-amide derivatives, their pharmaceutically acceptable salts and compositions thereof which are useful as antithrombotic agents in mammals and also the use of these compounds as antithrombotic agents. Also, described are methods of using these inhibitors as inhibitors of coagulation proteases and as therapeutic agents for disease states characterized by abnormal thrombus formation and/or disorders of the blood coagulation process. Further described herein are compounds useful as intermediates in the preparation of these compounds.

Abstract: Proteins which are potent anticoagulants and have at least one NAP domain and are described. These proteins having anticoagulant activity can be isolated from natural sources such as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.

Abstract: Proteins which are potent anticoagulants and have at least one NAP domain and are described. These proteins having anticoagulant activity can be isolated from natural sources such as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.

Abstract: Proteins which are potent anticoagulants and have at least one NAP domain and are described. These proteins having anticoagulant activity can be isolated from natural sources such as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.

Abstract: Proteins which are potent anticoagulants and have at least one NAP domain and are described. These proteins having anticoagulant activity can be isolated from natural sources such as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.

Abstract: A carry save adder (CSA) is adapted for use in dividing operations by providing it with a lookahead capability whereby it accurately predicts whether or not each of the proposed complemental subtractions in a division process could be successfully performed if actually attempted, and it actually performs only those subtractions that will not result in overdrafts. Each bit position of the carry save adder is arranged to receive sum, carry and data inputs and to furnish sum, carry, presum and precarry outputs. The sum and carry output bits are latched and remain undisturbed until the next complemental subtraction is performed.

Abstract: An imaging method is given whereby a latent electrostatographic image is developed by a developer containing liquid developer dispensing roll having excellent dimensional stability and resiliency having a thin, hard surface carrying the liquid developer on a resilient shell supported by a hard metal shaft.

Abstract: A sintered porous plaque battery plate comprises an elongated substrate and a sintered porous plaque on both major surfaces thereof. One longitudinal edge of the substrate has a region substantially free of porous plaque for welding a current collector thereto and the other opposed longitudinal edge of the substrate has a transversely tapered porous plaque region on both major surfaces of the plate adjacent and extending longitudinally of the opposed edge for preventing the plaque from chipping along the opposed edge. The method for forming such plates includes the steps of (1) coating a substrate with double and single plate width strips of powdered metal slurry, (2) forming a V-shaped groove longitudinally of each of said double width strips to define a tapered porous plaque region along one edge of each plate, and (3) severing the substrate into strips of plate each with a tapered edge region after the slurry has been sintered into a porous plate.

Abstract: A gas mask assembly for snouted animals is disclosed having a nose cap member for covering the nostrils and anterior portion of the animal's snout and having an opening therein for the attachment of a breathing tube. An abutment in the nose cap member prevents the animal's nostrils from becoming occluded by said nose cap member. A flexible sleeve member, formed from substantially gas impermeable material, is secured to the nose cap, and an immobilizing cinch is secured to the marginal portion of the sleeve member to afford sealing engagement for the sleeve member against the animal's snout and to restrain the animal's movements.

Abstract: Novel isocyanate-terminated polyether-based polymer prepolymers useful in urethane applications are produced by polymerization of one or more ethylenically unsaturated monomers in the presence of an isocyanate-terminated prepolymer obtained by reaction of an organic polyisocyanate with a polyhydroxy-containing adduct obtained by reacton of an alkylene oxide with a polyfunctional initiator containing two to six active hydrogen atoms. These isocyanate-terminated polyether-based polymers prepolymer compositions are useful in the preparation of flexible urethane foams and moisture-cured adhesives.