Abstract: This invention comprises peptides, methods and a kit for identifying DNA fragmentation in non-viable sperm. Specific peptide sequences are claimed that bind to ssDNA and fragmented DNA.

Abstract: A data base of species specific nucleotide sequences (SSN) is created. The chemically synthesized sequences are used as DNA sequencing primers. Different mixes of DNA primers allow for the rapid and unique identification of any pathogen previously identified in the species specific data base. Staphylococcus simulans can be identified as the causative agent of Interstitial Cystitis using the unique SSN sequence 5? ATG GAT GTT TCA AAA AAA GTA GCT 3? coding for pre-prolysostaphin using it as a differential DNA primer in a mix set of pathogenic SSN sequence primers.

Abstract: The Professor Pieczenik Instruction Method and System (PPIMS) allows students to learn contemporary scientific material economically and easily. It comprises hardware and software to record and make live lectures available to students and an internet contact point comprising information and communication with the lecturer. Data showing two grade point improvement for the majority of the class with the PPIMS in conceptually difficult molecular biology and biochemistry course instruction is presented.

Abstract: A Universal Binding Matrix is described which binds various classes of combinatorial libraries. This bound library can then be probed with test species of a simple or complex nature to identify complementary test species as well as test species surface mimics. These complementary test species have the characteristic of binding the test species as a pair. Tables of these paired sequences can then be used to identify interacting genomic codings. The utility is for lead and final compounds of a diagnostic, clinical and therapeutic nature, inter alit Other uses are found as research reagents, histological reagents, and new stains to cross correlate histology to pathology and the consequent ramification. Since the genomic coding of many organisms have been identified and found to have common correspondences, then these ligands can be used universally through the biosphere.

Abstract: A sperm-binding ligand sequence with the amino acid sequence HIPRTY is claimed. Using proprietary bio-informatic analysis, this sperm-binding ligand sequence was shown to also precisely correspond with a previously characterized highly conserved protein-protein interaction site in the Axin protein at position 370 to 375. The Axin protein sequence HIPRTY is found within the binding site of Axin to a known sperm surface protein, Glycogen Synthase Kinase-3. This result not only provides proof of the utility of this technique to identify cell surface ligands in mammalian gametes, but it also provides the first molecular data supporting a potential role for spermatozoa in facilitating developmental axis formation in mammalian embryos. The HIPRTY peptide can be useful in fertility therapy and diagnosis.

Abstract: A product and method of electronically trading stocks globally on their respective exchanges using a common currency, preferably U.S. currency.

Abstract: Insuring a product and method of electronically trading stocks globally on their respective exchanges using a common currency, preferably U.S. currency.

Abstract: The invention provides a product and methods of isolating a competitive population from a selective expansion of a predetermined target population of cells, including, inter-alia, the step of (a) reintroducing a selectively amplified population into a starting sample of cells into a growth medium. The invention provides for a competitively stable selectively expanded cell population. In addition, ligands isolated from combinatorial libraries are used as negative and positive cell selectors. A novel coated helical coil reaction vessel is described for continuous and programmable production.

Abstract: A Ligand Product and Method for Binding Amyloid Precursor Protein as a Diagnostic and Treatment Modality for Alzheimer's Disease and Other Neurological Syndromes

Abstract: Identification, Isolation and Use of Specific Ligands for Reproductive Science

Abstract: A method of inhibiting the growth of refractory tumors that are stimulated by mitogenic ligands of epidermal growth factor receptor in human patients, comprising treating the human patients with an effective amount of a mitogenic ligand antagonist.

Abstract: In one aspect the invention discloses a matrix comprising a discrete population of random oligopeptides of the same length, the length being selected from about 4 to about 12 L-amino acid residues, the population comprising at least 10% of all amino acid sequences of the selected length; and a heterogeneous population of antibodies comprising antibodies capable of binding to substantially every member of the oligopeptide population.

Abstract: In one aspect the invention discloses a matrix comprising a discrete population of random oligopeptides of the same length, the length being selected from about 4 to about 12 L-amino acid residues, the population comprising at least 10% of all amino acid sequences of the selected length; and a heterogeneous population of antibodies comprising antibodies capable of binding to substantially every member of the oligopeptide population.

Abstract: A conveniently portable dental cleaning instrument and kit for cleaning the interproximal area between teeth and crevices within and between teeth and gums are described. It can be constructed from siliconized paper, treated paper, cellophanes, and thin plastics. The preferred embodiment is a specific, double-sided siliconized paper, which has been determined to be of sufficient tensile strength, sturdiness, smoothness, having a low frictional coefficient, and flexible enough to be foldable without cracking. This embodiment allows the user to remove particles and plaque build-up in the interproximal spaces and dental crevices by using normal flossing and tooth-picking type strokes. Unlike flossing threads and wooden toothpicks, this invention will not dislodge fillings or remove loose caps, temporary caps, or bridge-work.This dental paper and kit can, also, be prepared with embedded microspheres containing flavors, sweeteners, dentifrices and antiseptics for additional hygienic, social, and anti-smoking uses.

Abstract: Autonomously replicating DNA containing a unique nucleotide sequence, being an oligonucleotide of which its sequence does not otherwise exist in said DNA[inserted in a non-essential region thereof at a site not previously susceptible of restriction endonuclease cleavage].

Abstract: Autonomously replicating DNA containing a unique nucleotide sequence, being an oligonucleotide of which its sequence does not otherwise exist in said DNA, inserted in a non-essential region thereof at a site not previously susceptible of restriction endonuclease cleavage.