Abstract: Provided herein are antibodies which bind to ceruloplasmin and are useful for various applications, including detecting ceruloplasmin and immunocapturing ceruloplasmin in biological samples. The antibodies are useful in methods of measuring non-ceruloplasmin-bound copper concentrations and labile-bound copper concentrations in biological samples.

Abstract: Systems and methods are disclosed for demographic prediction based on aggregated training data. The predictions are based on auditing aggregated data associated with identified properties of web requests. The audited information is based on a batch of prior web requests that have the same property and have been audited by a measurement company.

Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.

Abstract: The present disclosure describes a system that attempts to reconcile diverse goals and re-cast the goals into something that is quantifiable and optimizable. One way to reconcile diverse goals is by converting these “constraints”—with the huge problems of feasibility—into errors that can be minimized. This disclosure also presents solutions for rate constraints which previously have not been dealt with. The resulting system enables advertisers to dynamically adjust their campaign based on the needs of the moment. Such a system can have advantages in terms of controllability, smoothness, as well as avoiding hard stop conditions that plague the constraint-based approach. In order to achieve this result, solutions are presented for problems of pacing, viewability prediction, and most particularly, error minimization.

Abstract: The present disclosure describes a system that attempts to reconcile diverse goals and re-cast the goals into something that is quantifiable and optimizable. One way to reconcile diverse goals is by converting these “constraints”—with the huge problems of feasibility—into errors that can be minimized. This disclosure also presents solutions for rate constraints which previously have not been dealt with. The resulting system enables advertisers to dynamically adjust their campaign based on the needs of the moment. Such a system can have advantages in terms of controllability, smoothness, as well as avoiding hard stop conditions that plague the constraint-based approach. In order to achieve this result, solutions are presented for problems of pacing, viewability prediction, and most particularly, error minimization.

Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.

Abstract: The present disclosure describes a system that attempts to reconcile diverse goals and re-cast the goals into something that is quantifiable and optimizable. One way to reconcile diverse goals is by converting these “constraints”—with the huge problems of feasibility—into errors that can be minimized. This disclosure also presents solutions for rate constraints which previously have not been dealt with. The resulting system enables advertisers to dynamically adjust their campaign based on the needs of the moment. Such a system can have advantages in terms of controllability, smoothness, as well as avoiding hard stop conditions that plague the constraint-based approach. In order to achieve this result, solutions are presented for problems of pacing, viewability prediction, and most particularly, error minimization.

Abstract: Systems and methods are disclosed for demographic prediction based on aggregated training data. The predictions are based on auditing aggregated data associated with identified properties of web requests. The audited information is based on a batch of prior web requests that have the same property and have been audited by a measurement company.

Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.

Abstract: Antibodies that neutralize Notum Pectinacetylesterase are described, as well as compositions comprising them, and methods of their use to treat diseases and disorders affecting the bone.

Abstract: A non-contact apparatus is provided for monitoring the height of contents of a moving container, such as a beverage can 24 on a conveyor 14. The apparatus comprises non-contact ultrasonic wave generation means comprising a first electromagnetic acoustic transducer 16 disposed to one side of a container 24 being monitored and adapted to produce an ultrasonic wave pulse in the container, and non-contact ultrasonic wave detector means comprising a second electromagnetic acoustic transducer 18 adapted to detect an ultrasonic signal and to generate a detection signal dependent upon the ultrasonic signal which is detected, the detector means being disposed at a different position to the side of a container 24 from the generation means. The apparatus further including signal processing means 20 adapted to process the detection signal generated by the ultrasonic wave detector means using the difference in transit times for two waves to provide an indication of the level of the contents in the container 24.

Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Abstract: The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described NHP.

Abstract: The present invention relates to methods and compositions for the treatment of biological disorders regulatable by the controlled expression or inhibition of the described NHP.

Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Abstract: A method of making a stacked three-dimensional refractive index structure in photosensitive materials using photo-patterning where first determined is the wavelength at which a photosensitive material film exhibits a change in refractive index upon exposure to optical radiation, a portion of the surfaces of the photosensitive material film is optically irradiated, the film is marked to produce a registry mark. Multiple films are produced and aligned using the registry marks to form a stacked three-dimensional refractive index structure.

Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Abstract: A structural member including a web portion having a plurality of triangular regions to provide additional strength and stiffness. The triangular regions are recessed from the web and may have a floor area or the floor may be cut out to provide apertures with lip portions. An additional element secures a flanged bracing panel in the opening between the studs and the top and bottom plates of a building frame and clads both sides of the braced frame.

Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Abstract: A method of making a three-dimensional refractive index structure in a photosensitive material using photo-patterning. The wavelengths at which a photosensitive material exhibits a change in refractive index upon exposure to optical radiation is first determined and then a portion of the surface of the photosensitive material is optically irradiated at a wavelength at which the photosensitive material exhibits a change in refractive index using a designed illumination system to produce a three-dimensional refractive index structure. The illumination system can be a micro-lenslet array, a macroscopic refractive lens array, or a binary optic phase mask. The method is a single-step, direct-write procedure to produce a designed refractive index structure.