Patents by Inventor George Preti

George Preti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170227491
    Abstract: Provided are devices and methods to detect the presence of volatile organic compounds related to the presence of a disease state in a biological sample. The devices may include a detection moiety such as a polynucleotide in electronic communication with a semiconductor such as graphene or a carbon nanotube.
    Type: Application
    Filed: September 3, 2015
    Publication date: August 10, 2017
    Inventors: Alan T. JOHNSON, Nicholas J. KYBERT, George PRETI, Katharine A. PRIGGE, Janos L. TANYI, Cynthia OTTO
  • Patent number: 9381142
    Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: July 5, 2016
    Assignees: Monell Chemical Senses Center, Symrise Inc.
    Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
  • Publication number: 20100254927
    Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.
    Type: Application
    Filed: June 16, 2010
    Publication date: October 7, 2010
    Applicants: Monell Chemical Senses Center, Symrise, Inc.
    Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
  • Patent number: 7763238
    Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.
    Type: Grant
    Filed: January 15, 2003
    Date of Patent: July 27, 2010
    Assignees: Monell Chemical Senses Center, Symrise Inc.
    Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
  • Publication number: 20080031844
    Abstract: Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described.
    Type: Application
    Filed: January 4, 2006
    Publication date: February 7, 2008
    Applicant: Monell Chemical Senses Center
    Inventors: George Preti, Charles Wysocki
  • Publication number: 20070020210
    Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.
    Type: Application
    Filed: August 30, 2006
    Publication date: January 25, 2007
    Inventors: George Preti, Charles Wysocki, Leslie Smith, Keith McDermott
  • Patent number: 7056948
    Abstract: Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: June 6, 2006
    Assignee: Monell Chemical Senses Center
    Inventors: George Preti, Charles Wysocki
  • Publication number: 20030152538
    Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.
    Type: Application
    Filed: January 15, 2003
    Publication date: August 14, 2003
    Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
  • Publication number: 20020046710
    Abstract: Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described.
    Type: Application
    Filed: June 22, 2001
    Publication date: April 25, 2002
    Inventors: George Preti, Charles Wysocki
  • Patent number: 5877223
    Abstract: Certain volatile compounds naturally present in herring gull eggs are effective for repelling animals and birds, particularly canids, from the locus to which such compounds are applied. More particularly, the volatile compounds which are effective animal repellents include compounds exhibiting mint-like odors such as the compounds pulegone and piperitone. The invention relates to methods of using these compounds to repel animals, and to repellent compositions comprising effective repellent amounts of such compounds.
    Type: Grant
    Filed: March 8, 1990
    Date of Patent: March 2, 1999
    Assignee: Monell Chemical Senses Center
    Inventors: James Russell Mason, Richard Albert Dolbeer, George Preti
  • Patent number: 5538719
    Abstract: It has now been found that cross-adaptation may occur between two structurally-similar compounds with qualitatively different odors. The perceived intensity of a malodor, for example, underarm sweat, may be decreased by cross-adaptation to at least one ester compound structurally similar to a component of such sweat. Such structurally similar compounds may be used in methods for decreasing the perceived intensity of a malodor such as sweat, in products designed to cover the characteristic odor of sweat, and in methods for covering malodor.
    Type: Grant
    Filed: March 25, 1994
    Date of Patent: July 23, 1996
    Assignee: Monell Chemical Senses Center
    Inventors: George Preti, John D. Pierce, Jr., Xiao-Nong Zeng, Charles J. Wysocki
  • Patent number: 5155045
    Abstract: A novel method for treating a human female is disclosed comprising the step of exposing the nasal region of said female to at least a portion of the axillary secretions of a human male. This exposure is preferably continued in amounts and for a duration which are effective to significantly alter an endocrine related characteristic, such as the menstrual cycle length, of that female. In particular, the portions of male axillary secretions to be exposed to the female preferably comprise one or more compounds such as androstenol, dehydroepiandrosterone, and/or a compound or compounds exhibiting a burnt heavy axiallary-like odor which elutes at about 50 minutes as shown on the FID response curve of FIG. 3B. Studies show that pooled male donor secretions are effective to alter aberrant menstrual cycles, particularly those exhibiting luteal phase defects such that they become presumptively fertile menstrual cycles having durations of about 29.5.+-.3 days.
    Type: Grant
    Filed: April 30, 1986
    Date of Patent: October 13, 1992
    Assignee: Trustees of the University of Penn.
    Inventors: Winnifred B. Cutler, George Preti, Celso R. Garcia
  • Patent number: 4931403
    Abstract: A novel method of determining the onset of the fertile period of a human female is disclosed comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehydroepiandrosterone sulfate. A first significant increase in the concentration of either of those compounds following the cessation of menses is indicative of the onset of the fertile period. In each case, a follicular phase peak occurs which exceeds by at least twice the concentration of those compounds present at any other time during the menstrual cycle. As a result, the monitoring of these compounds may act as reliable indicators predicting the occurrence of ovulation in five to seven days, and/or indicating the onset of the fertile period at a time when appropriate contraceptive measures can still be taken to avoid pregnancy or sexual intercourse can promote fertility.
    Type: Grant
    Filed: August 7, 1989
    Date of Patent: June 5, 1990
    Assignees: Monell Chemical Senses Center, University of Pa.
    Inventors: Winnifred B. Cutler, George Preti, George R. Huggins
  • Patent number: 4879244
    Abstract: A novel method of determining the onset of the fertile period of a human female is disclosed comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehydroepiandrosterone sulfate. A first significant increase in the concentration of either of those compounds following the cessation of menses is indicative of the onset of the fertile period. In each case, a follicular phase peak occurs which exceeds by at least twice the concentration of those compounds present at any other time during the menstrual cycle. As a result, the monitoring of these compounds may act as reliable indicators predicting the occurrence of ovulation in five to seven days, and/or indicating contraceptive measures can still be taken to avoid pregnancy or sexual intercourse can promote fertility.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: November 7, 1989
    Assignees: Monell Chemical Senses Center, University of Pennsylvania
    Inventors: Winnifred B. Cutler, George Preti, George R. Huggins
  • Patent number: 4772559
    Abstract: A novel method of detecting and diagnosing lung cancers by monitoring and analyzing expired lung air for the presence of selected aromatic amines, particularly aniline and ortho-toluidine, is provided.
    Type: Grant
    Filed: March 31, 1987
    Date of Patent: September 20, 1988
    Assignees: Monell Chemical Senses Center, University of Pennsylvania
    Inventors: George Preti, John N. Labows, Ronald Daniele, James G. Kostelc
  • Patent number: 4670401
    Abstract: Method for determining the onset of the fertile period of a human female comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehydroepiandrosterone sulfate. A first significant increase in the concentration of either of those compounds following the cessation of menses is indicative of the onset of the fertile period. In each case, a follicular phase peak occurs which exceeds by at least twice the concentration of those compounds present at any other time during the menstrual cycle. As a result, the monitoring of these compounds may act as reliable indicators predicting the occurrence of ovulation in five to seven days, and/or indicating the onset of the fertile period at a time when appropriate contraceptive measures can still be taken to avoid pregnancy or sexual intercourse can promote fertility.
    Type: Grant
    Filed: January 25, 1985
    Date of Patent: June 2, 1987
    Assignees: Monell Chemical Senses Center, University of Pennsylvania
    Inventors: Winnifred B. Cutler, George Preti, George R. Huggins
  • Patent number: 4467814
    Abstract: A novel method for determining when cows are in estrus is disclosed comprising the step of monitoring the vaginal secretions of a cow to determine an increase in the amount of an indicator compound in said secretions. A significant increase in the amount of the indicator compound, concentrations above about 0.1 micrograms per gram of collected secretion, is indicative of estrus. The preferred indicator alcohols have ethyl ester indices of 8.1 to 8.9. In particular these alcohols are methyl-1-heptanols, such as 6-methyl-1-heptanol, or are methyl hydroxy heptenes, such as 2-methyl-7 hyroxy-.DELTA.-3-4 heptene. Alternatively, a cow may be determined to be in estrus simply to ascertaining that the concentration of methyl-1-heptanol is at least 0.1 microgram per gram of collected vaginal secretion.
    Type: Grant
    Filed: March 19, 1982
    Date of Patent: August 28, 1984
    Assignee: Monell Chemical Senses Center
    Inventor: George Preti
  • Patent number: 4385125
    Abstract: Method for precisely ascertaining the time of ovulation by monitoring the concentration of alcohols in the range of C.sub.10 -C.sub.16, particularly dodecanol. A spike in the concentration of such compound(s) is indicative of time of ovulation.
    Type: Grant
    Filed: November 14, 1980
    Date of Patent: May 24, 1983
    Assignee: Monell Chemical Senses Center
    Inventors: George Preti, James G. Kostelc, Joseph Tonzetich, George R. Huggins
  • Patent number: 4334540
    Abstract: A novel method of diagnosing periodontal disease is disclosed wherein telltale pyridine and alkyl-pyridine compounds which are detected in the oral cavity are indicative of periodontal disease. An alternate embodiment method is disclosed wherein increased concentrations of certain other compounds are detected to confirm the presence of periodontal disease.
    Type: Grant
    Filed: May 1, 1979
    Date of Patent: June 15, 1982
    Assignee: Monell Chemical Senses Center
    Inventors: George Preti, James G. Kostelc, Philip R. Zelson
  • Patent number: 4119089
    Abstract: A novel method is provided for precisely predicting and then ascertaining the time of ovulation by monitoring the mouth air of a female, a first peak after menses in the concentration of said volatile sulfur-containing compounds in said mouth air predicting ovulation by about 5 to 7 days, and a second increase thereafter being indicative of ovulation. Alternatively, a method is provided wherein TPTZ is utilized to sense secondary characteristics associated with the production of volatile sulfur compounds for the purpose of providing a simple colorimetric home test for determining the precise time of ovulation.
    Type: Grant
    Filed: February 2, 1977
    Date of Patent: October 10, 1978
    Assignee: Trustees of the University of Pennsylvania
    Inventors: George Preti, George R. Huggins, Joseph Tonzetich