Patents by Inventor George Preti
George Preti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230118692Abstract: Provided are devices and methods to detect the presence of volatile organic compounds related to the presence of a disease state in a biological sample. The devices may include a detection moiety such as a polynucleoide in electronic communication with a semiconductor such as graphene or a carbon nanotube.Type: ApplicationFiled: June 28, 2022Publication date: April 20, 2023Inventors: Alan T. Johnson, Nicholas J. Kybert, George Preti, Katharine A. Prigge, Janos L. Tanyi, Cynthia Otto
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Patent number: 11415546Abstract: Provided are devices and methods to detect the presence of volatile organic compounds related to the presence of a disease state in a biological sample. The devices may include a detection moiety such as a polynucleotide in electronic communication with a semiconductor such as graphene or a carbon nanotube.Type: GrantFiled: September 3, 2015Date of Patent: August 16, 2022Assignees: The Trustees of the University of Pennsylvania, Monell Chemical Senses CenterInventors: Alan T. Johnson, Nicholas J. Kybert, George Preti, Katharine A. Prigge, Janos L. Tanyi, Cynthia Otto
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Patent number: 10828242Abstract: The present invention belongs to the area of body odour modelling. In particular, the developed synthetic compositions of the present invention reconstitute human body odours, especially those arising from axillary perspiration. The use of the compositions herein allows for the evaluation of malodour masking effects of fragrant compositions in the field of personal care or homecare products and cosmetic product development.Type: GrantFiled: October 22, 2015Date of Patent: November 10, 2020Assignees: Symrise AG, Monell Chemical Senses CenterInventors: Marco Singer, Keith McDermott, Marcela Olalde-Castillo, George Preti, Charles Wysocki, Katherine Ashley Prigge
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Publication number: 20190105250Abstract: The present invention belongs to the area of body odour modelling. In particular, the developed synthetic compositions of the present invention reconstitute human body odours, especially those arising from axillary perspiration. The use of said compositions allows for the evaluation of malodour masking effects of fragrant compositions in the field of personal care or homecare products and cosmetic product development.Type: ApplicationFiled: October 22, 2015Publication date: April 11, 2019Applicants: Symrise AG, Monell Chemical Senses CenterInventors: Marco Singer, Keith McDermott, Marcela Olalde-Castillo, George Preti, Charles Wysocki, Katherine Ashley Prigge
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Publication number: 20170227491Abstract: Provided are devices and methods to detect the presence of volatile organic compounds related to the presence of a disease state in a biological sample. The devices may include a detection moiety such as a polynucleotide in electronic communication with a semiconductor such as graphene or a carbon nanotube.Type: ApplicationFiled: September 3, 2015Publication date: August 10, 2017Inventors: Alan T. JOHNSON, Nicholas J. KYBERT, George PRETI, Katharine A. PRIGGE, Janos L. TANYI, Cynthia OTTO
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Patent number: 9381142Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.Type: GrantFiled: June 16, 2010Date of Patent: July 5, 2016Assignees: Monell Chemical Senses Center, Symrise Inc.Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
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Publication number: 20100254927Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.Type: ApplicationFiled: June 16, 2010Publication date: October 7, 2010Applicants: Monell Chemical Senses Center, Symrise, Inc.Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
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Patent number: 7763238Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.Type: GrantFiled: January 15, 2003Date of Patent: July 27, 2010Assignees: Monell Chemical Senses Center, Symrise Inc.Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
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Publication number: 20080031844Abstract: Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described.Type: ApplicationFiled: January 4, 2006Publication date: February 7, 2008Applicant: Monell Chemical Senses CenterInventors: George Preti, Charles Wysocki
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Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents
Publication number: 20070020210Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.Type: ApplicationFiled: August 30, 2006Publication date: January 25, 2007Inventors: George Preti, Charles Wysocki, Leslie Smith, Keith McDermott -
Patent number: 7056948Abstract: Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described.Type: GrantFiled: June 22, 2001Date of Patent: June 6, 2006Assignee: Monell Chemical Senses CenterInventors: George Preti, Charles Wysocki
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Publication number: 20030152538Abstract: Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants.Type: ApplicationFiled: January 15, 2003Publication date: August 14, 2003Inventors: George Preti, Charles J. Wysocki, Leslie C. Smith, Keith J. McDermott
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Publication number: 20020046710Abstract: Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described.Type: ApplicationFiled: June 22, 2001Publication date: April 25, 2002Inventors: George Preti, Charles Wysocki
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Patent number: 5877223Abstract: Certain volatile compounds naturally present in herring gull eggs are effective for repelling animals and birds, particularly canids, from the locus to which such compounds are applied. More particularly, the volatile compounds which are effective animal repellents include compounds exhibiting mint-like odors such as the compounds pulegone and piperitone. The invention relates to methods of using these compounds to repel animals, and to repellent compositions comprising effective repellent amounts of such compounds.Type: GrantFiled: March 8, 1990Date of Patent: March 2, 1999Assignee: Monell Chemical Senses CenterInventors: James Russell Mason, Richard Albert Dolbeer, George Preti
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Patent number: 5538719Abstract: It has now been found that cross-adaptation may occur between two structurally-similar compounds with qualitatively different odors. The perceived intensity of a malodor, for example, underarm sweat, may be decreased by cross-adaptation to at least one ester compound structurally similar to a component of such sweat. Such structurally similar compounds may be used in methods for decreasing the perceived intensity of a malodor such as sweat, in products designed to cover the characteristic odor of sweat, and in methods for covering malodor.Type: GrantFiled: March 25, 1994Date of Patent: July 23, 1996Assignee: Monell Chemical Senses CenterInventors: George Preti, John D. Pierce, Jr., Xiao-Nong Zeng, Charles J. Wysocki
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Patent number: 5155045Abstract: A novel method for treating a human female is disclosed comprising the step of exposing the nasal region of said female to at least a portion of the axillary secretions of a human male. This exposure is preferably continued in amounts and for a duration which are effective to significantly alter an endocrine related characteristic, such as the menstrual cycle length, of that female. In particular, the portions of male axillary secretions to be exposed to the female preferably comprise one or more compounds such as androstenol, dehydroepiandrosterone, and/or a compound or compounds exhibiting a burnt heavy axiallary-like odor which elutes at about 50 minutes as shown on the FID response curve of FIG. 3B. Studies show that pooled male donor secretions are effective to alter aberrant menstrual cycles, particularly those exhibiting luteal phase defects such that they become presumptively fertile menstrual cycles having durations of about 29.5.+-.3 days.Type: GrantFiled: April 30, 1986Date of Patent: October 13, 1992Assignee: Trustees of the University of Penn.Inventors: Winnifred B. Cutler, George Preti, Celso R. Garcia
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Patent number: 4931403Abstract: A novel method of determining the onset of the fertile period of a human female is disclosed comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehydroepiandrosterone sulfate. A first significant increase in the concentration of either of those compounds following the cessation of menses is indicative of the onset of the fertile period. In each case, a follicular phase peak occurs which exceeds by at least twice the concentration of those compounds present at any other time during the menstrual cycle. As a result, the monitoring of these compounds may act as reliable indicators predicting the occurrence of ovulation in five to seven days, and/or indicating the onset of the fertile period at a time when appropriate contraceptive measures can still be taken to avoid pregnancy or sexual intercourse can promote fertility.Type: GrantFiled: August 7, 1989Date of Patent: June 5, 1990Assignees: Monell Chemical Senses Center, University of Pa.Inventors: Winnifred B. Cutler, George Preti, George R. Huggins
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Patent number: 4879244Abstract: A novel method of determining the onset of the fertile period of a human female is disclosed comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehydroepiandrosterone sulfate. A first significant increase in the concentration of either of those compounds following the cessation of menses is indicative of the onset of the fertile period. In each case, a follicular phase peak occurs which exceeds by at least twice the concentration of those compounds present at any other time during the menstrual cycle. As a result, the monitoring of these compounds may act as reliable indicators predicting the occurrence of ovulation in five to seven days, and/or indicating contraceptive measures can still be taken to avoid pregnancy or sexual intercourse can promote fertility.Type: GrantFiled: January 20, 1987Date of Patent: November 7, 1989Assignees: Monell Chemical Senses Center, University of PennsylvaniaInventors: Winnifred B. Cutler, George Preti, George R. Huggins
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Patent number: 4772559Abstract: A novel method of detecting and diagnosing lung cancers by monitoring and analyzing expired lung air for the presence of selected aromatic amines, particularly aniline and ortho-toluidine, is provided.Type: GrantFiled: March 31, 1987Date of Patent: September 20, 1988Assignees: Monell Chemical Senses Center, University of PennsylvaniaInventors: George Preti, John N. Labows, Ronald Daniele, James G. Kostelc
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Patent number: 4670401Abstract: Method for determining the onset of the fertile period of a human female comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehydroepiandrosterone sulfate. A first significant increase in the concentration of either of those compounds following the cessation of menses is indicative of the onset of the fertile period. In each case, a follicular phase peak occurs which exceeds by at least twice the concentration of those compounds present at any other time during the menstrual cycle. As a result, the monitoring of these compounds may act as reliable indicators predicting the occurrence of ovulation in five to seven days, and/or indicating the onset of the fertile period at a time when appropriate contraceptive measures can still be taken to avoid pregnancy or sexual intercourse can promote fertility.Type: GrantFiled: January 25, 1985Date of Patent: June 2, 1987Assignees: Monell Chemical Senses Center, University of PennsylvaniaInventors: Winnifred B. Cutler, George Preti, George R. Huggins