Patents by Inventor George R. Greene

George R. Greene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200138450
    Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.
    Type: Application
    Filed: December 20, 2019
    Publication date: May 7, 2020
    Applicant: MicroVention, Inc.
    Inventors: George R. Greene, JR., Ivan Sepetka, Cathy Lei, Alejandro Berenstein, Monika Killer-Oberpfalzer, Heath Bowman
  • Patent number: 10555738
    Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: February 11, 2020
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Ivan Sepetka, Cathy Lei, Alejandro Berenstein, Monika Killer-Oberpfalzer, Heath Bowman
  • Publication number: 20190192165
    Abstract: A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.
    Type: Application
    Filed: February 28, 2019
    Publication date: June 27, 2019
    Applicants: MicroVention, Inc., University of Virginia Patent Foundation, United States of America As Represented By The Secretary Of The Navy
    Inventors: George R. Greene, JR., Ivan Sepetka, Cathy Lei, Rupal Nguyen, Matthew J. Bradley, Stephen T. Ahlers, Carl W. Goforth, James R. Stone
  • Publication number: 20180317926
    Abstract: An expansile member that may be used on a delivery device or may be used for occlusive purposes within the vasculature.
    Type: Application
    Filed: July 11, 2018
    Publication date: November 8, 2018
    Applicant: MicroVention, Inc.
    Inventors: Hideo Morita, Greg Bak-Boychuk, Arnold Tuason, Matthew J. Fitz, George R. Greene
  • Publication number: 20180250058
    Abstract: An embolic agent and a piezoelectric substance are mixed together. The mixture can be delivered to a tumor or other object by a non-invasive method. The embolic agent prevents movement of the piezoelectric substance from the target location. Subsequent impulses applied to the target location cause ablation of the surrounding area due to the piezoelectric effect of the particles, promoting highly accurate and precise ablation without the need for more invasive procedures.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 6, 2018
    Inventors: Bharathi Jagadeesan, Sean Lester Moen, George R. Greene, JR.
  • Patent number: 10045786
    Abstract: An expansile member that may be used on a delivery device or may be used for occlusive purposes within the vasculature.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: August 14, 2018
    Assignee: MicroVention, Inc.
    Inventors: Hideo Morita, Greg Bak-Boychuk, Arnold Tuason, Matthew J. Fitz, George R. Greene, Jr.
  • Publication number: 20180070955
    Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.
    Type: Application
    Filed: October 17, 2017
    Publication date: March 15, 2018
    Applicant: MicroVention, Inc.
    Inventors: George R. Greene, JR., Ivan Sepetka, Cathy Lei, Alejandro Berenstein, Monika Killer-Oberpfalzer, Heath Bowman
  • Publication number: 20180055515
    Abstract: A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.
    Type: Application
    Filed: August 29, 2017
    Publication date: March 1, 2018
    Applicant: MicroVention, Inc.
    Inventors: George R. Greene, JR., Ivan Sepetka, Cathy Lei, Rupal Nguyen
  • Publication number: 20170367713
    Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.
    Type: Application
    Filed: May 18, 2017
    Publication date: December 28, 2017
    Applicant: MicroVention, Inc.
    Inventors: George R. Greene, JR., Ivan Sepetka, Cathy Lei, Alejandro Berenstein, Monika Killer-Oberpfalzer
  • Publication number: 20150174381
    Abstract: An expansile member is described. The expansile member may be used on a delivery device or may be used for occlusive purposes within the vasculature.
    Type: Application
    Filed: November 19, 2014
    Publication date: June 25, 2015
    Inventors: Hideo Morita, Greg Bak-Boychuk, Arnold Tuason, Matthew J. Fitz, George R. Greene, JR.
  • Patent number: 9034005
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: May 19, 2015
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Publication number: 20140257245
    Abstract: Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 11, 2014
    Applicant: MicroVention, Inc.
    Inventors: Robert F. Rosenbluth, George R. Greene, JR., Brian J. Cox, Thomas S. Sternweiler, Sean L. Chow, Richard R. Monetti, Teresa L. Halverson, Maricela D. Walker, Robert Pecor
  • Patent number: 8603128
    Abstract: An embolization device for occluding a body cavity includes one or more elongated, expansible, hydrophilic embolizing elements non-releasably carried along the length of an elongated filamentous carrier that is preferably made of a very thin, highly flexible filament or microcoil of nickel/titanium alloy. At least one expansile embolizing element is non-releasably attached to the carrier. A first embodiment includes a plurality of embolizing elements fixed to the carrier at spaced-apart intervals along its length. In second, third and fourth embodiments, an elongate, continuous, coaxial embolizing element is non-releasably fixed to the exterior surface of the carrier, extending along a substantial portion of the length of the carrier proximally from a distal tip, and optionally includes a lumenal reservoir for delivery of therapeutic agents. Exemplary methods for making these devices include skewering and molding the embolizing elements.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: December 10, 2013
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Gregory M. Cruise, Michael Constant, Brian J. Cox, Terrance Tran
  • Patent number: 8323306
    Abstract: A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. Confinement of the device within an aneurysm causes it to assume a three-dimensional configuration with a higher energy state than the minimum energy state. Because the minimum energy state configuration of the device is larger (in at least one dimension) than the aneurysm, the deployed device is constrained by its contact with the walls of the aneurysm from returning to its minimum energy state configuration. The engagement of the device with the aneurysm wall minimizes shifting or tumbling due to blood flow.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: December 4, 2012
    Assignee: MicroVention, Inc.
    Inventors: Dean Schaefer, Brian J. Cox, George R. Greene, Jr., David A. Ferrera, Matthew Fitz, Robert F. Rosenbluth
  • Patent number: 7976527
    Abstract: A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: July 12, 2011
    Assignee: Micro Therapeutics, Inc.
    Inventors: Andrew H. Cragg, Blair D. Walker, John Perl, II, Michael Jones, George R. Greene, George Wallace, Richard J. Greff
  • Publication number: 20110005062
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Application
    Filed: September 8, 2010
    Publication date: January 13, 2011
    Inventors: George R. Greene, JR., Robert F. Rosenbluth, Brian J. Cox
  • Patent number: 7842054
    Abstract: An embolization device for occluding a body cavity includes one or more elongated, expansible, hydrophilic embolizing elements non-releasably carried along the length of an elongated filamentous carrier that is preferably made of a very thin, highly flexible filament or microcoil of nickel/titanium alloy. At least one expansile embolizing element is non-releasably attached to the carrier. A first embodiment includes a plurality of embolizing elements fixed to the carrier at spaced-apart intervals along its length. In second, third and fourth embodiments, an elongate, continuous, coaxial embolizing element is non-releasably fixed to the exterior surface of the carrier, extending along a substantial portion of the length of the carrier proximally from a distal tip, and optionally includes a lumenal reservoir for delivery of therapeutic agents. Exemplary methods for making these devices include skewering and molding the embolizing elements.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: November 30, 2010
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Gregory M. Cruise, Michael Constant, Brian J. Cox, Terrance Tran
  • Patent number: 7799047
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: September 21, 2010
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Publication number: 20090232869
    Abstract: An embolization device for occluding a body cavity includes one or more elongated, expansible, hydrophilic embolizing elements non-releasably carried along the length of an elongated filamentous carrier that is preferably made of a very thin, highly flexible filament or microcoil of nickel/titanium alloy. At least one expansile embolizing element is non-releasably attached to the carrier. A first embodiment includes a plurality of embolizing elements fixed to the carrier at spaced-apart intervals along its length. In second, third and fourth embodiments, an elongate, continuous, coaxial embolizing element is non-releasably fixed to the exterior surface of the carrier, extending along a substantial portion of the length of the carrier proximally from a distal tip, and optionally includes a lumenal reservoir for delivery of therapeutic agents. Exemplary methods for making these devices include skewering and molding the embolizing elements.
    Type: Application
    Filed: January 29, 2009
    Publication date: September 17, 2009
    Inventors: George R. Greene, JR., Gregory M. Cruise, Michael Constant, Brian J. Cox, Terrance Tran
  • Publication number: 20090112250
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Application
    Filed: December 17, 2008
    Publication date: April 30, 2009
    Inventors: George R. Greene, JR., Robert F. Rosenbluth, Brian J. Cox