Abstract: Methods and systems for generating sterile cold solution are provided. The cold solution may be injected into subcutaneous fat of a subject to facilitate weight reduction or improve cosmetic appearances. The systems include a repository for receiving a solution, a generator for generating the cold solution from the solution, and a port for transferring the cold solution from the system. The generator includes a cooling device, a heat exchanger, and a recirculating fluid path configured to circulate a fluid which may include air. The methods include receiving a solution in the system, generating the cold solution from the solution, and transferring the cold solution from the system, wherein generating the cold solution includes circulating a fluid which may include air.

Abstract: A semiconductor device includes an insulating layer, a first semiconductor layer over the insulating layer, a diffusion break structure between a first active region and a second active region and including a first insulating pattern over the insulating layer and an opening over the first insulating pattern, and a conductive gate material over the opening.

Abstract: A laryngeal mask airway device includes an airway tube and a laryngeal mask placed at a distal end of the airway tube. The distal end of the airway tube opens inside the laryngeal mask. The device includes a connector placed at a proximal end of the airway tube. The connector is in fluid communication with the laryngeal mask through the airway tube and is configured to be connected to a ventilation equipment. The device includes a movable element placed in the laryngeal mask and configured to steer a tip of a catheter passing through the airway tube. The device further includes a control element mounted on the proximal end of the airway tube and a motion transmission device operatively connected to the movable element and to the control element to move the movable element and to steer the tip of the catheter by acting on the control element.

Abstract: Systems and methods for providing cybersecurity notifications based on structured and unstructured data. The systems and methods receive a natural language query from a client device and processes, by an artificial intelligence model, the natural language query to identify elements of cybersecurity intelligence to monitor. The systems and methods further monitor cybersecurity intelligence for a match to the identified elements from the natural language query and provide a notification to the client device in response to the matching of the identified elements to one or more items of cybersecurity intelligence.

Abstract: A structure includes a substrate, a first transistor on the substrate and a second transistor on the substrate. The second transistor is spaced apart from the first transistor by an isolation region. At least one stress-inducing liner is over the first transistor and the second transistor. An opening extends through at least one stress-inducing liner over at least the isolation region, and a dielectric layer is in at least a portion of the opening. The structure allows for local enhanced high-pressure deuterium (HPD) passivation, which increases threshold voltage of the transistors and improves hot carrier injection with no additional masking. A method of forming the structure is also provided.

Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.

Abstract: A perineal probe (10) having a probe body which includes electronic members (110, 111, 112) configured to interact with perineal muscles of the patient. The probe body has a cylindrical portion (12) configured to be positioned at the opening of the body cavity of a patient, and a flared portion (13) which extends from one end (121) of the cylindrical portion (12). The flared portion (13) extends widening from the cylindrical portion (12) as far as a free upper end (130), with the flared portion (13) being elastically deformable between a retracted position and a deployed position. The electronic members (110, 111, 112) are arranged on the flared portion (13) and/or on the cylindrical portion (12).

Abstract: A security service can determine a synthetic context based at least in part on context data associated with a first malware sample, and detonate the first malware sample in the synthetic context to provide one or more first event records representing events performed by the first malware sample and detected during detonation. Additionally or alternatively, the security service can detonate the first malware sample and locate a second malware sample in a corpus based at least in part on the one or more first event records. Additionally or alternatively, the security service can receive event records representing events detected during a detonation of a first malware sample, the detonation based at least in part on context data, and locate a second malware sample in the corpus based at least in part on the one or more reference event records.

Abstract: Deception-based techniques for responding to security attacks are described herein. The techniques include transitioning a security attack to a monitored computing device posing as a computing device impacted by the security attack and enabling the adversary to obtain deceptive information from the monitored computing device. Also, the adversary may obtain a document configured to report identifying information of an entity opening the document, thereby identifying the adversary associated with the attack. Further, the techniques include determining that a domain specified in a domain name request is associated with malicious activity and responding to the request with a network address of a monitored computing device to cause the requesting process to communicate with the monitored computing device in place of an adversary server. Additionally, a service may monitor dormant domains names associated with malicious activity and, in response to a change, respond with an alert or a configuration update.

Abstract: A method of producing a compound formula (I) the method comprising: reacting a compound of formula (II) with a compound of formula (III) wherein, R3 is hydrogen or halogen; R1 and R2 are each independently C1-C6alkoxy, or R1 and R2 together are ?O or —OCH2CH2O— or —OCH2CH2CH2O—; and optionally whereby the reaction is carried out in the presence of an oxidizer.

Abstract: Providing virtualized credentials of a license holder includes determining contextual data that governs visual information presented on a display and displaying credential data on the display, where visual characteristics of the credential data that is displayed varies according to the contextual data. The display may be a display on a device of the license holder or a display on a device that is viewable by a relying party. The visual characteristics may be modified according to a location of at least some of the credential data on the display on the device of the license holder, a particular font used, a particular color used for text, a color scheme of an existing image and/or a specific image that is independent of the credential data. The visual characteristics may be modified according to the color scheme by changing a background color on the screen of the device of the license holder.

Abstract: A syringe, a kit, methods of making and methods of using the same are provided. The syringe includes a syringe body defining an interior volume. The syringe body defines a first opening at a distal end for dispensing and a second opening at a proximal end. The syringe further includes a stopper disposed inside the barrel, optionally a stopper insert coupled with the stopper, and a plunger rod disposed outside the syringe body. The plunger rod has a first end, a second end, and a middle section. The middle section is disposed along the barrel wall. The first end of the plunger rod is configured to be coupled with the stopper or the stopper insert, and the second end is reversibly attached to the distal end or the proximal end of the syringe body. The plunger rod can be detached and assembled with the stopper or the stopper insert so as to drive the stopper for injection.

Abstract: An integrated circuit (IC) device is disclosed which includes a first transistor over a substrate. The first transistor includes a gate over the substrate and between a source region and a drain region. The transistor further includes a first region of vertically-graded silicon germanium (“SiGe”) adjacent a first side of a channel under the gate, and a second region of vertically-graded SiGe adjacent a second side of the channel. The channel includes substantially uniformly-graded SiGe.

Abstract: A security service can determine a synthetic context based at least in part on context data associated with a first malware sample, and detonate the first malware sample in the synthetic context to provide one or more first event records representing events performed by the first malware sample and detected during detonation. Additionally or alternatively, the security service can detonate the first malware sample and locate a second malware sample in a corpus based at least in part on the one or more first event records. Additionally or alternatively, the security service can receive event records representing events detected during a detonation of a first malware sample, the detonation based at least in part on context data, and locate a second malware sample in the corpus based at least in part on the one or more reference event records.

Abstract: A compound of formula (I)

Abstract: A compound: and double bond regioisomers thereof.

Abstract: A one-time programmable (OTP) fuse includes a trench isolation; a gate metal layer over the trench isolation; and a PN junction over the gate metal layer. More particularly, the OTP fuse may include a first terminal including a highly doped n-type polysilicon layer over the trench isolation, and a second terminal including a highly doped p-type polysilicon layer over the trench isolation. The highly doped n-type polysilicon layer contacts the highly doped p-type polysilicon layer, creating a PN junction and a fuse link defined in a portion of the gate metal layer between the trench isolation and the PN junction. The gate metal layer has a uniform thickness that allows better dimension control of the fuse link to reduce fuse programming current variability.

Abstract: Provided herein are various embodiments relating to antibodies. Some of the embodiments include antagonist antibodies that bind PD-1. Such antibodies can be used in methods to treat, for example, cancer.

Abstract: Deception-based techniques for responding to security attacks are described herein. The techniques include transitioning a security attack to a monitored computing device posing as a computing device impacted by the security attack and enabling the adversary to obtain deceptive information from the monitored computing device. Also, the adversary may obtain a document configured to report identifying information of an entity opening the document, thereby identifying the adversary associated with the attack. Further, the techniques include determining that a domain specified in a domain name request is associated with malicious activity and responding to the request with a network address of a monitored computing device to cause the requesting process to communicate with the monitored computing device in place of an adversary server. Additionally, a service may monitor dormant domains names associated with malicious activity and, in response to a change, respond with an alert or a configuration update.