Patents by Inventor George S. Drummond

George S. Drummond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STANNSOPORFIN COMPOSITIONS AND ADMINISTRATION
    Publication number: 20080261939
    Abstract: Pharmaceutical compositions including stannsoporfin, drug products incorporating pharmaceutical compositions, methods of making pharmaceutical compositions, and methods of treating hyperbilirubinemia with drug products and compositions are disclosed.
    Type: Application
    Filed: April 22, 2008
    Publication date: October 23, 2008
    Inventors: George S. Drummond, Philip C. Lang
  • PREPARATION OF METAL MESOPORPHYRIN COMPOUNDS
    Publication number: 20080154033
    Abstract: A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.
    Type: Application
    Filed: December 14, 2007
    Publication date: June 26, 2008
    Inventors: Robert Vukovich, Benjamin Levinson, George S. Drummond, Robert Caroselli, Kazimierz G. Antczak, Christopher Boucher, Richard Mortimer, Danny Levin, Keith A. Cooke
  • HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN
    Publication number: 20080125585
    Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.
    Type: Application
    Filed: October 4, 2007
    Publication date: May 29, 2008
    Inventors: George S. DRUMMOND, Robert Caroselli, Keith A. Cooke, Daniel Levin, David G. Roe, Christopher P. Boucher
  • Preparation of metal mesoporphyrin compounds
    Patent number: 7375216
    Abstract: A method of preparing metal mesoporphyrin compounds is described. A metal mesoporphyrin compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: May 20, 2008
    Assignee: InfaCare Pharmaceutical Corporation
    Inventors: Robert Vukovich, Benjamin Levinson, George S. Drummond, Robert Caroselli, Kazimierz G. Antczak, Christopher Boucher, Richard Mortimer, Danny Levin, Keith A. Cooke
  • Preparation of metal mesoporphyrin halide compounds
    Patent number: 6818763
    Abstract: A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: November 16, 2004
    Assignee: Wellspring Pharmaceutical Corporation
    Inventors: Robert A. Vukovich, Benjamin Levinson, George S. Drummond, Robert Caroselli, Kazimierz G. Antczak, Christopher Boucher, Richard Mortimer
  • Preparation of metal mesoporphyrin halide compounds
    Publication number: 20040210048
    Abstract: A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.
    Type: Application
    Filed: March 29, 2004
    Publication date: October 21, 2004
    Applicant: WellSpring Pharmaceutical Corporation
    Inventors: Robert Vukovich, Benjamin Levinson, George S. Drummond, Robert Caroselli, Kazimierz G. Antczak, Christopher Boucher, Richard Mortimer, Danny Levin, Keith A. Cooke
  • Water-soluble mesoporphyrin compounds and methods of preparation
    Publication number: 20040097481
    Abstract: Water soluble tin mesoporphyrin compounds are described. Methods of preparation of water soluble metal mesoporphyrin compounds and pharmaceutical preparations are also described.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 20, 2004
    Inventors: Benjamin Levinson, George S. Drummond
  • Preparation of metal mesoporphyrin halide compounds
    Publication number: 20030225264
    Abstract: A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.
    Type: Application
    Filed: June 3, 2003
    Publication date: December 4, 2003
    Inventors: Robert A. Vukovich, Benjamin Levinson, George S. Drummond, Robert Caroselli, Kazimierz G. Antczak, Christopher Boucher, Richard Mortimer
  • Orally administered porphyrins to control intestinal iron absorption
    Patent number: 5223494
    Abstract: Disclosed is a pharmaceutical composition for oral administration to control heme oxygenase comprising mettaloprotoporhyrins and mettalomesoporphyrins.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: June 29, 1993
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, Daniel W. Rosenberg, George S. Drummond
  • Control of heme and iron concentrations in body tissues
    Patent number: 5162313
    Abstract: The administration of tin protoporphyrin, tin mesoporphyrin or tin diiododeuteroporphyrin to mammals, notably humans, increases the rate at which heme is excreted by mammals, and is useful for treatment of body tissue injury associated with hemorrhage in the body.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: November 10, 1992
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Method of controlling T.sub.3 and T.sub.4 levels in vivo with cobalt porphyrins
    Patent number: 5087622
    Abstract: Method of decreasing the production of thyroid hormones in animals by parenteral administration of defined quantities of cobalt protoporphyrin or cobalt mesoporphyrin.
    Type: Grant
    Filed: March 23, 1990
    Date of Patent: February 11, 1992
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Methods for suppressing the endocrine system
    Patent number: 5084475
    Abstract: Cobalt protoporphyrin and cobalt mesoporphyrin are administered to animals to achieve weight loss and improve protein to fat ratio.
    Type: Grant
    Filed: March 23, 1990
    Date of Patent: January 28, 1992
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Method for suppressing the endocrine system
    Patent number: 5066650
    Abstract: Method for limiting the production of estrogenic steroids by parenteral administration of selected amounts of cobalt protoporphyrin or cobalt mesoporphyrin.
    Type: Grant
    Filed: January 8, 1991
    Date of Patent: November 19, 1991
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Method of controlling androstene levels in vivo with cobalt porphyrins
    Patent number: 5063223
    Abstract: Method of reducing the production of gonadal estrogenic steroidal hormones in animals by parenteral administration of defined quantities of cobalt protoporphyrin or cobalt mesoporphyrin.
    Type: Grant
    Filed: March 23, 1990
    Date of Patent: November 5, 1991
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Use of liposomes as carriers for metalloporphyrins
    Patent number: 5010073
    Abstract: Pharmaceutical copositions comprising liposomal metalloporphyrins are provided for parenteral administration to mammals, including humans. These liposomal metalloporphyrins selectively target the spleen and markedly inhibit the heme oxygenase activity therein. A method is also provided for intravenous administration of these compositions to mammals to selectively target the spleen.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: April 23, 1991
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Methods for suppressing the endocrine system
    Patent number: 4948792
    Abstract: This invention relates to the parenteral administration of cobalt protoporphyrin and cobalt mesoporphyrin to suppress the endocrine system of animals to achieve physiological effects such as suppression of the production of gonadal or thyroid hormones, control of weight gain and improved protein to fat ratio.
    Type: Grant
    Filed: February 14, 1989
    Date of Patent: August 14, 1990
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
    Patent number: 4782049
    Abstract: Use of tin protoporphyrin and tin mesoporphyrin together with ultraviolet light in the treatment of psoriasis.
    Type: Grant
    Filed: December 2, 1987
    Date of Patent: November 1, 1988
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond, Lennart Emtestam
  • Therapeutic use of tin diiododeuteroporphyrin
    Patent number: 4699903
    Abstract: Use of the novel compound tin diiododeuteroporphyrin and compositions containing it to inhibit heme mebabolism in mammals, to control the rate of tryptophan metabolism in mammals, and to increase the rate at which heme and iron are excreted by mammals.
    Type: Grant
    Filed: January 29, 1987
    Date of Patent: October 13, 1987
    Assignee: The Rockefeller University
    Inventors: Darryl Rideout, Attallah Kappas, George S. Drummond
  • Therapeutic use of tin diiododeuteroporphyrin
    Patent number: 4692439
    Abstract: Use of the novel compound tin diiododeuteroporphyrin and compositions containing it to inhibit heme metabolism in mammals, to control the rate of tryptophan metabolism in mammals, and to increase the rate at which heme and iron are excreted by mammals.
    Type: Grant
    Filed: January 29, 1987
    Date of Patent: September 8, 1987
    Assignee: The Rockefeller University
    Inventors: Darryl Rideout, Attallah Kappas, George S. Drummond
  • Therapeutic use of tin mesoporphyrin
    Patent number: 4692440
    Abstract: Use of the novel compound tin mesoporphyrin and compositions containing it to inhibit heme metabolism in mammals, to control the rate of tryptophan metabolism in mammals, and to increase the rate at which heme is excreted by mammals.
    Type: Grant
    Filed: October 24, 1986
    Date of Patent: September 8, 1987
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond