Abstract: A method of obtaining yellow-orange coloration of egg yolks and chicken skins using 4-ketolutein as feed additive for chicken feed.

Abstract: A compound of formula (A) or salt thereof: wherein each of R1, R2, and R3 independently represents hydrogen, alkyl, aryl, acyl, sulfonyl, or silyl; P represents hydrogen or a hydroxy protective group. This compound may be used an intermediate for making a 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleosides, such as gemcitabine.

Abstract: A process of preparing an alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate, which is useful as an intermediate in the preparation of a beta nucleoside, such as gemcitabine, an anti-tumor agent. A beta-2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate is heated and converted to an alpha-2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate in the absence of an effective amount of a sulfonate salt to facilitate the conversion. In addition, an anomeric mixture of an alpha-anomer and a beta-anomer of 2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate can be dissolved in a mixture of water and a solvent and heated to produce a lactol, which may be further converted to an alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate.

Abstract: The present invention relates to the use of an astaxanthin pigment product obtained by semi-synthesis from marigold extract to substantially enhance the feeding and growth rates of commercially cultivated aquatic species when added to the feed mixture in concentrations useful in producing fish and shrimp coloration. More particularly, this product induces growth rates substantially greater than any currently available feed additive for salmon, trout and shrimp.

Abstract: The present invention provides for an efficient method of effecting the resolution of a narwedine amide, and the synthesis of galantamine.

Abstract: A method for preparation of 4-ketolutein from lutein is described. The product is useful as a feed additive to provide desirable coloration for egg yolks and chicken skins.

Abstract: A process of preparing an alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate, which is useful as an intermediate in the preparation of a beta nucleoside, such as gemcitabine, an anti-tumor agent. A beta-2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate is heated and converted to an alpha-2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate in the absence of an effective amount of a sulfonate salt to facilitate the conversion. In addition, an anomeric mixture of an alpha-anomer and a beta-anomer of 2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate can be dissolved in a mixture of water and a solvent and heated to produce a lactol, which may be further converted to an alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofunanosyl sulfonate.

Abstract: The present invention relates to the use of an astaxanthin pigment product obtained by semi-synthesis from marigold extract to substantially enhance the feeding and growth rates of commercially cultivated aquatic species when added to the feed mixture in concentrations useful in producing fish and shrimp coloration. More particularly, this product induces growth rates substantially greater than any currently available feed additive for salmon, trout and shrimp.

Abstract: The present invention provides for an efficient method of effecting the resolution of a narwedine amide, and the synthesis of galantamine.

Abstract: The present invention provides a method of converting an intermediate compound to the desired S,S diastereomer for efficiently making benazepril and analogues thereof.

Abstract: The present invention provides an efficient synthetic process for making benazepril and analogues thereof by having an intermediate compound undergo epimerization and kinetic resolution.

Abstract: The present invention provides a novel semi-synthetic method of producing a variety of novel taxane derivatives. The method involves the reaction of a phenylisoserine derivative with a suitably blocked Baccatin III derivative to produce a taxane substrate that may be further modified to form Pactitaxel and other potentially useful taxane derivatives.

Abstract: The present invention provides a method of converting an intermediate compound to the desired S,S diastereomer for efficiently making benazepril and analogues thereof.

Abstract: The present invention provides a novel semi-synthetic method of producing a variety of novel taxane derivatives. The method involves the reaction of a phenylisoserine derivative with a suitably blocked Baccatin III derivative to produce a taxane substrate that may be further modified to form Pactitaxel and other potentially useful taxane derivatives.