Patents by Inventor George Scott Wilson

George Scott Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Forms of cidofovir
    Patent number: 9505792
    Abstract: Cidofovir is obtained in different forms, including amorphous cidofovir, crystalline anhydrous cidofovir, crystalline cidofovir monohydrate, and crystalline cidofovir dihydrate, including various polymorphs.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: November 29, 2016
    Assignee: Johnson Matthey Public Limited Company
    Inventors: George Scott Wilson, Angela Barkley, Jurjus Jurayj
  • FORMS OF CIDOFOVIR
    Publication number: 20150175640
    Abstract: Cidofovir is obtained in different forms, including amorphous cidofovir, crystalline anhydrous cidofovir, crystalline cidofovir monohydrate, and crystalline cidofovir dihydrate, including various polymorphs.
    Type: Application
    Filed: March 4, 2015
    Publication date: June 25, 2015
    Inventors: George Scott Wilson, Angela Barkley, Jurjus Jurayj
  • Forms of cidofovir
    Patent number: 8999958
    Abstract: Cidofovir is obtained in different forms, including amorphous cidofovir, crystalline anhydrous cidofovir, crystalline cidofovir monohydrate, and crystalline cidofovir dihydrate, including various polymorphs.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: April 7, 2015
    Assignee: Johnson Matthey Public Limited Company
    Inventors: George Scott Wilson, Angela Barkley, Jurjus Jurayj
  • Process for reducing the 6-keto group of a morphinan alkaloid to the 6-hydroxy group by hydrogenation
    Patent number: 8853402
    Abstract: A process for the reduction of a 6-keto group in a morphinan alkaloid to the corresponding 6-hydroxy group includes hydrogenating the 6-keto group using gaseous hydrogen in the presence of a heterogeneous catalyst and a solvent, to yield the 6-hydroxy morphinan alkaloid, wherein the reduction is carried out at a pH in the range of about 5 to about 7, and the 6-hydroxy morphinan alkaloid has an ?:? ratio of >85:15.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: October 7, 2014
    Assignee: Johnson Matthey Public Limited Company
    Inventors: George Scott Wilson, Maureen Joan Young
  • Preparation of opiate analgesics by reductive alkylation
    Patent number: 8318937
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: November 27, 2012
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • FORMS OF CIDOFOVIR
    Publication number: 20120277191
    Abstract: Cidofovir is obtained in different forms, including amorphous cidofovir, crystalline anhydrous cidofovir, crystalline cidofovir monohydrate, and crystalline cidofovir dihydrate, including various polymorphs.
    Type: Application
    Filed: April 6, 2012
    Publication date: November 1, 2012
    Applicant: Johnson Matthey Public Limited Company
    Inventors: George Scott Wilson, Angela Barkley, Jurjus Jurayj
  • PROCESS FOR REDUCING THE 6-KETO GROUP OF A MORPHINAN ALKALOID TO THE 6-HYDROXY GROUP BY HYDROGENATION
    Publication number: 20120209002
    Abstract: The present invention relates to a process for the reduction of a 6-keto group in a morphinan alkaloid to the corresponding 6-hydroxy group, comprising hydrogenating the 6-keto group using gaseous hydrogen in the presence of a heterogenous catalyst and a solvent, to yield the 6-hydroxy morphinan alkaloid, wherein the reduction is carried out at a pH in the range of about 5 to about 7, and the 6-hydroxy morphinan alkaloid has an ?:? ratio of >85:15.
    Type: Application
    Filed: August 13, 2010
    Publication date: August 16, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: George Scott Wilson, Maureen Joan Young
  • PREPARATION OF OPIATE ANALGESICS BY REDUCTIVE ALKYLATION
    Publication number: 20120046466
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Application
    Filed: February 18, 2011
    Publication date: February 23, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • Preparation of opiate analgesics by reductive alkylation
    Patent number: 8119803
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, (CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process includes reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: February 21, 2012
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • Process for the synthesis of morphinane compounds and intermediates thereof
    Patent number: 8106201
    Abstract: This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.
    Type: Grant
    Filed: January 3, 2011
    Date of Patent: January 31, 2012
    Assignees: Johnson Matthey Public Limited Company, GlaxoSmithKline Australia Pty. Ltd.
    Inventors: Craig Smith, Stuart Purcell, Lucy Waddell, Nicholas Hayes, Jarrod Ritchie, Scott Brian Halliday, Melville Mitchell, George Scott Wilson
  • PREPARATION OF OPIATE ANALGESICS BY REDUCTIVE ALKYLATION
    Publication number: 20110144341
    Abstract: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)2OH, C(CH3)(C(CH3)3)OH or COCH3; Z is C2-C10 alkyl or C2-C10 arylalkyl; and is a single bond or a double bond, is disclosed. The process is a reductive alkylation in the presence of hydrogen and a reductive alkylation catalyst.
    Type: Application
    Filed: February 18, 2011
    Publication date: June 16, 2011
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Melville Mitchell, Neil Kenneth Thomson, George Scott Wilson, Neil John Goodwin, Maureen Joan Young
  • PROCESS FOR THE SYNTHESIS OF MORPHINANE COMPOUNDS AND INTERMEDIATES THEREOF
    Publication number: 20110098474
    Abstract: This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.
    Type: Application
    Filed: January 3, 2011
    Publication date: April 28, 2011
    Applicants: JOHNSON MATTHEY PUBLIC LIMITED COMPANY, GLAXOSMITHKLINE AUSTRALIA PTY. LTD.
    Inventors: Craig Smith, Stuart Purcell, Lucy Waddell, Nicholas Hayes, Jarrod Ritchie, Scott Brian Halliday, Melville Mitchell, George Scott Wilson
  • Process for the synthesis of morphinane compounds and intermediates thereof
    Patent number: 7875718
    Abstract: This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: January 25, 2011
    Assignees: Johnson Matthey Public Limited Company, GlaxoSmithKline Australia Pty. Ltd.
    Inventors: Craig Smith, Stuart Purcell, Lucy Waddell, Nicholas Hayes, Jarrod Ritchie, Scott Brian Halliday, Melville Mitchell, George Scott Wilson