Abstract: The present invention relates to a method for the treatment of cancer in a patient in need thereof. The method comprises administering to a patient in need thereof a first amount of a histone deacetylase inhibitor in a first treatment procedure, and a second amount or dose of radiation in a second treatment procedure. The first and second treatments together comprise a therapeutically effective amount. The combination of the HDAC inhibitor and radiation therapy is therapeutically synergistic.

Abstract: The present invention provides targeted delivery of alpha particle-emitting radionuclides and their alpha-emitting progeny using liposomal encapsulation to prevent the loss of daughter radionuclides from the targeting vehicle and, therefore, from the tumor site.

Abstract: A method of imaging a characteristic of image intensity of an imaging agent in a subject consists of introducing the imaging agent into the subject and repetitively scanning the subject at each of a plurality of time intervals, so as to produce a plurality of time-sequenced images throughout the subject. Each of the time-sequenced images is then subdivided into a notional array of image elements such that there is a one-to-one correspondence between positions of image elements in the array and locations in the subject. Thereafter, a value of image intensity of the imaging agent at the corresponding location in the subject is determined for each image element in each of the time-sequenced images, the image elements in the arrays of successive time-sequenced images being in register with each other with respect to the locations.